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Revenues (Tables)
3 Months Ended
Mar. 31, 2022
Revenue from Contract with Customer [Abstract]  
Disaggregation of revenue by product and by geographic area
Revenues were as follows (in millions):
Three months ended March 31,
20222021
U.S.ROWTotalU.S.ROWTotal
Enbrel$843 $19 $862 $894 $30 $924 
Prolia582 270 852 501 257 758 
XGEVA368 134 502 334 134 468 
Otezla350 101 451 366 110 476 
Aranesp137 221 358 125 230 355 
Neulasta304 44 348 421 61 482 
Repatha165 164 329 139 147 286 
KYPROLIS196 91 287 159 92 251 
Nplate156 110 266 112 115 227 
Other products936 540 1,476 852 513 1,365 
Total product sales(1)
$4,037 $1,694 5,731 $3,903 $1,689 5,592 
Other revenues507 309 
Total revenues$6,238 $5,901 
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(1)    Hedging gains and losses, which are included in product sales, were not material for the three months ended March 31, 2022 and 2021.