Goodwill and other intangible assets - Identifiable Intangible Assets (Details) - USD ($) $ in Millions	Dec. 31, 2021	Dec. 31, 2020
Finite-lived intangible assets:
Gross carrying amounts	$ 32,099	$ 32,018
Accumulated amortization	(17,987)	(15,461)
Other intangible assets, net	14,112	16,557
Indefinite-lived intangible assets:
Identifiable intangible assets	33,169	32,048
Accumulated amortization	(17,987)	(15,461)
Identifiable intangible assets, net	15,182	16,587
IPR&D
Indefinite-lived intangible assets:
Indefinite-lived intangible assets	1,070	30
Developed Technology Rights
Finite-lived intangible assets:
Gross carrying amounts	25,561	25,591
Accumulated amortization	(12,769)	(10,564)
Other intangible assets, net	12,792	15,027
Licensing rights
Finite-lived intangible assets:
Gross carrying amounts	3,807	3,743
Accumulated amortization	(2,973)	(2,791)
Other intangible assets, net	834	952
Marketing-related rights [Member]
Finite-lived intangible assets:
Gross carrying amounts	1,354	1,367
Accumulated amortization	(1,112)	(1,041)
Other intangible assets, net	242	326
R&D technology rights [Member]
Finite-lived intangible assets:
Gross carrying amounts	1,377	1,317
Accumulated amortization	(1,133)	(1,065)
Other intangible assets, net	$ 244	$ 252