Acquisitions - Aggregate Consideration Paid (Details) - USD ($) $ in Millions			12 Months Ended
	Oct. 19, 2021	Nov. 21, 2019	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Business Acquisition [Line Items]
Additions			$ 309	$ 0	$ 0
Goodwill			$ 14,890	$ 14,689	$ 14,703
Teneobio
Business Acquisition [Line Items]
Cash paid	$ 994
Additions	309
Business asset acquisition, consideration transferred	1,303
Cash and cash equivalents	100
Goodwill	251
Other assets, net	16
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities	(253)
Total assets acquired, net	1,303
Teneobio | R & D Technology rights
Business Acquisition [Line Items]
Finite-lived intangible assets	94
Teneobio | Licensing rights
Business Acquisition [Line Items]
Finite-lived intangible assets	41
Teneobio | IPR&D
Business Acquisition [Line Items]
IPR&D	$ 1,054
Otezla
Business Acquisition [Line Items]
Cash paid		$ 13,400
Transaction costs		40
Business asset acquisition, consideration transferred		13,440
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Deferred Tax Liabilities		(24)
Deferred credit		(96)
Other liabilities, net		(9)
Inventory		367
Total assets acquired, net		13,440
Otezla | Developed Technology Rights
Business Acquisition [Line Items]
Finite-lived intangible assets		13,007
Otezla | Marketing-Related Rights
Business Acquisition [Line Items]
Finite-lived intangible assets		$ 195