Property, plant and equipment (Tables)

12 Months Ended

Dec. 31, 2021

Property, Plant and Equipment [Abstract]

Components of property, plant and equipment

Property, plant and equipment consisted of the following (dollar amounts in millions):

		December 31,
	Useful life (in years)	2021		2020
Land	—	$	279	$	259
Buildings and improvements	10-40	4,028		3,857
Manufacturing equipment	8-12	3,080		2,865
Laboratory equipment	8-12	1,193		1,257
Fixed equipment	12	2,402		2,406
Capitalized software	3-5	1,151		1,216
Other	5-10	862		1,091
Construction in progress	—	987		915
Property, plant and equipment, gross		13,982		13,866
Less accumulated depreciation and amortization		(8,798)		(8,977)
Property, plant and equipment, net		$	5,184	$	4,889

Property, plant and equipment by geographic information

Certain geographic information with respect to property, plant and equipment, net (long-lived assets), was as follows (in millions):

	December 31,
	2021		2020
United States	$	2,801	$	2,473
Puerto Rico	1,311		1,331
ROW	1,072		1,085
Total property, plant and equipment, net	$	5,184	$	4,889