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Derivative instruments (Summary of Income and Expense Line Items) (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Derivative Instruments, Gain (Loss) [Line Items]    
Interest and other income, net $ 185 $ 231
Interest expense, net (343) (338)
Amortization of cumulative amount of fair value hedging adjustments for discontinued hedging relationships 3  
Interest rate swap agreements [Member]    
Derivative Instruments, Gain (Loss) [Line Items]    
Gains (losses) on fair value hedging relationships, Hedged items (130)  
Gains (losses) on fair value hedging relationships, Derivatives designated as hedging instruments 133  
Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash flow hedges [Member] | Cross-currency swap contracts [Member]    
Derivative Instruments, Gain (Loss) [Line Items]    
Interest and other income, net (42)  
Product sales [Member]    
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales 5,286 $ 5,343
Product sales [Member] | Reclassification out of Accumulated Other Comprehensive Income [Member] | Cash flow hedges [Member] | Foreign currency contracts [Member]    
Derivative Instruments, Gain (Loss) [Line Items]    
Product sales $ 14