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Goodwill and intangible assets (Identifiable Intangible Assets) (Details) - USD ($)
$ in Millions
Dec. 31, 2016
Dec. 31, 2015
Finite-lived intangible assets:    
Gross carrying amount $ 18,264 $ 17,905
Accumulated amortization (8,744) (7,279)
Intangible assets, net 9,520 10,626
Indefinite-lived intangible assets:    
Identifiable intangible assets 19,023 18,920
Accumulated amortization (8,744) (7,279)
Identifiable intangible assets, net 10,279 11,641
IPR&D [Member]    
Indefinite-lived intangible assets:    
Indefinite-lived intangible assets 759 1,015
Developed product technology rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 12,534 12,310
Accumulated amortization (5,947) (4,996)
Intangible assets, net 6,587 7,314
Licensing rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 3,275 3,275
Accumulated amortization (1,300) (998)
Intangible assets, net 1,975 2,277
Marketing-related rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 1,333 1,186
Accumulated amortization (793) (650)
Intangible assets, net 540 536
R&D technology rights [Member]    
Finite-lived intangible assets:    
Gross carrying amount 1,122 1,134
Accumulated amortization (704) (635)
Intangible assets, net $ 418 $ 499