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Collaborative arrangements (Bayer HealthCare Pharmaceuticals Inc.) (Details) - Bayer [Member] - Nexavar [Member]
$ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2013
USD ($)
Dec. 31, 2015
USD ($)
country
Dec. 31, 2014
USD ($)
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Number of countries product is marketed and sold | country   100  
Collaboration, royalty percentage in the high 30s   30.00%  
Percentage of net profits after deducting certain partner related costs   50.00%  
Other revenues [Member]      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Collaboration profit $ 78 $ 257 $ 324
Royalty income   $ 72