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Note 3 - Significant Accounting Policies - Research and Development Expense (Details) - General and Administrative Expense [Member] - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Research and development cost $ 21,047 $ 80,351 $ 108,128 $ 198,882
Research and Development, Salaries [Member]        
Research and development cost 7,047 68,158 69,727 159,237
Research and Development, Other Costs [Member]        
Research and development cost $ 14,000 $ 12,193 $ 38,401 $ 39,645