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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 JTiiAryMb7JOaFXhtbN+eXe50nGmaK4DrKdPXXFXOXvp7bu4E67N9mI5E5lq0mWP
 LWlBH29XVpMGjErcbfVYyw==

<SEC-DOCUMENT>0000930413-08-000783.txt : 20080206
<SEC-HEADER>0000930413-08-000783.hdr.sgml : 20080206
<ACCEPTANCE-DATETIME>20080206193855
ACCESSION NUMBER:		0000930413-08-000783
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080204
FILED AS OF DATE:		20080206
DATE AS OF CHANGE:		20080206

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ENZO BIOCHEM INC
		CENTRAL INDEX KEY:			0000316253
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		IRS NUMBER:				132866202
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			0731

	BUSINESS ADDRESS:	
		STREET 1:		60 EXECUTIVE BLVD
		CITY:			FARMINGDALE
		STATE:			NY
		ZIP:			11735
		BUSINESS PHONE:		5167555500

	MAIL ADDRESS:	
		STREET 1:		ENZO BIOCHEM INC
		STREET 2:		60 EXECUTIVE BLVD
		CITY:			FARMINGDALE
		STATE:			NY
		ZIP:			11735

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			GOLDBERG DAVID C
		CENTRAL INDEX KEY:			0001251336

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-09974
		FILM NUMBER:		08582838

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		2125830100

	MAIL ADDRESS:	
		STREET 1:		C/O ENZO BIOCHEM INC
		STREET 2:		527 MADISON AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>c52252_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-02-04</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000316253</issuerCik>
        <issuerName>ENZO BIOCHEM INC</issuerName>
        <issuerTradingSymbol>ENZ</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001251336</rptOwnerCik>
            <rptOwnerName>GOLDBERG DAVID C</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ENZO BIOCHEM INC</rptOwnerStreet1>
            <rptOwnerStreet2>527 MADISON AVE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>VP, Business Development</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Restricted Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-02-04</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>94391</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On February 4, 2008, the Reporting Person was granted 2,000 shares of restricted common stock, par value $.01 (the
 &quot;Restricted Stock&quot;) as compensation for serving as a officer of the Issuer. The Restricted Stock is subject to a three-year
 vesting period, subject to acceleration in certain circumstances.</footnote>
        <footnote id="F2">As of the date hereof, the Reporting Person directly beneficially owned 41,972 shares of Common Stock, 979 shares indirectly
 beneficially owned through the UGMA accounts of the Reporting Person's children, 3,102 shares of Common Stock in the
 Issuer's 401(K) Plan and 48,338 options to purchase Common Stock, par value $0.01 per share, which are currently
 exercisable. The Reporting Person also owns 2,000 shares of Restricted Stock that are not deemed to be beneficially owned
 because they are not exercisable within the next 60 days.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ David Goldberg</signatureName>
        <signatureDate>2008-02-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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