February 13, 2020

Kai Haakon E. Liekefett, Esq.
Sidley Austin LLP
787 Seventh Avenue
New York, NY 10019

       Re:    Enzo Biochem, Inc.
              Preliminary Proxy Statement filed on February 11, 2020
              File No. 001-09974

Dear Mr. Liekefett:

     We have reviewed the above filing and related response letter and have the
following
comments.

1.     We note your response to prior comment 1. We reissue the portion of the
comment
       requesting a description of the procedural requirements to postpone an
annual meeting.

2.     In addition, please confirm in your response letter that if quorum had
been established at
       the January 31 meeting, the Board could still have adjourned the meeting
over the
       objection of holders of the majority of shares present in person or by
proxy or a majority
       of shares of the voting stock outstanding. In responding to this portion
of the comment,
       please address NY BCL section 608(d), In re Dollinger Corp., 274
N.Y.S.2d 285, 287
       (N.Y. Sup Ct. 1966)("It is the shareholders' meeting, the owners of the
company, who
       have the right to make a decision on a question of adjournment, and not
of the president
       who has only the duty of presiding.") and Article 1, Section 6 of the
By-Laws, including
       the penultimate sentence thereto ("[i]n the absence of a quorum, the
holders of a majority
       of the votes of the shares of stock present in person or by proxy and
entitled to vote, or if
       no shareholder entitled to vote is present, then any officer of the
Corporation may adjourn
       the meeting from time to time"). We note that the authority cited in the
response to prior
       comment 1 to support the directors' ability to adjourn a meeting is that
of the Delaware
       Court of Chancery as opposed to that of a New York court.

3.     Please advise us as to what communication, if any, the Company provided
to
       shareholders to clarify that notwithstanding that the meeting was
"delayed" until
       February 25, as disclosed in the January 28 press release filed as
additional definitive
       material on January 29, 2020, that the meeting would still be held on
January 31 in order
       for it to be adjourned.

                                            *    *   *
 Kai Haakon E. Liekefett, Esq.
Sidley Austin LLP
February 13, 2020
Page 2

        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

       Please contact me at (202) 551-3444 with any questions.

                                                          Sincerely,

                                                          /s/ Perry J. Hindin

                                                          Perry J. Hindin
                                                          Special Counsel
                                                          Office of Mergers and
Acquisitions