144 0000316011 XXXXXXXX LIVE 0000059478 ELI LILLY AND CO 001-06351 2801 NORTH MERIDIAN STREET INDIANAPOLIS IN 46208-0068 3172762000 LILLY ENDOWMENT INC 10% Stockholder Common Stock Fidelity Capital Markets

640 Fifth Avenue New York NY 10019

205000 95083100 949272933 07/21/2023 NYSE, NASDAQ Common Stock 02/10/1948 Gift J.K. Lilly Sr. Trust Y 01/21/1937 38400000 N/A N Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 04/28/2023 225000 89657617.5 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 05/02/2023 41698 17085592.88 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 05/03/2023 178302 76028721.67 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 05/12/2023 20646 9141433.55 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 05/19/2023 194354 86024267.81 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/15/2023 27353 12422241.86 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/16/2023 25015 11394287.47 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/20/2023 34156 15509590.64 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/21/2023 31454 14284308.82 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/22/2023 107022 49153556.46 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/28/2023 11760 5473169.86 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/29/2023 44115 20517145.37 Lilly Endowment, Inc.

2801 North Meridian Street Indianapolis IN 46208

Eli Lilly and Company Common Stock 06/30/2023 164125 76744357.63 07/21/2023 /s/ Ben W. Blanton