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      </invstOrSec>
      <invstOrSec>
        <name>NEUROGENE INC</name>
        <lei>529900A7VIY892SZVW73</lei>
        <title>NEUROGENE INC</title>
        <cusip>64135M105</cusip>
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          <isin value="US64135M1053"/>
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        <balance>177200.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ASCENDIS PHARMA A/S</name>
        <lei>549300B66JN3W3J8GH73</lei>
        <title>ASCENDIS PHARMA AS</title>
        <cusip>N/A</cusip>
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          <isin value="DK0060615755"/>
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        <balance>269225.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>DK</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>BIOGEN INC</name>
        <lei>W8J5WZB5IY3K0NDQT671</lei>
        <title>BIOGEN INC</title>
        <cusip>09062X103</cusip>
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          <isin value="US09062X1037"/>
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        <balance>294100.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>CELLDEX THERAPEUTICS INC</name>
        <lei>529900F018DMYWH38923</lei>
        <title>CELLDEX THERAPEUTICS INC</title>
        <cusip>15117B202</cusip>
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          <isin value="US15117B2025"/>
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        <balance>512352.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>19500117.12000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>AVALO THERAPEUTICS INC</name>
        <lei>549300GPK6FPJ3X8SZ39</lei>
        <title>AVALO THERAPEUTICS INC</title>
        <cusip>05338F306</cusip>
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          <isin value="US05338F3064"/>
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        <balance>639700.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CYTOMX THERAPEUTICS INC</name>
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        <cusip>23284F105</cusip>
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          <isin value="US23284F1057"/>
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        <balance>2490551.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>DBV TECHNOLOGIES SA</name>
        <lei>969500PVBQFWQKVDMD80</lei>
        <title>DBV TECHNOLOGIES SA SPON ADR</title>
        <cusip>23306J309</cusip>
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          <isin value="US23306J3095"/>
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        <balance>428800.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>FR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Fidelity Revere Street Trust</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Cash Central Fund</title>
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          <isin value="US31635A1051"/>
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        <balance>8490313.34900000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Fidelity Revere Street Trust</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Securities Lending Cash Central Fund</title>
        <cusip>31635A303</cusip>
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          <isin value="US31635A3032"/>
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        <balance>43210105.46300000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>GILEAD SCIENCES INC</name>
        <lei>549300WTZWR07K8MNV44</lei>
        <title>GILEAD SCIENCES INC</title>
        <cusip>375558103</cusip>
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          <isin value="US3755581036"/>
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        <balance>963500.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>125457335.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CRESCENT BIOPHARMA INC</name>
        <lei>549300TZ84FFU2J2J459</lei>
        <title>CRESCENT BIOPHARMA INC</title>
        <cusip>N/A</cusip>
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          <isin value="KYG2545C1042"/>
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        <balance>356090.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>INSMED INC</name>
        <lei>529900Q55QAG41CCAC11</lei>
        <title>INSMED INC</title>
        <cusip>457669307</cusip>
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          <isin value="US4576693075"/>
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        <balance>680300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>67077580.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>NATERA INC</name>
        <lei>529900CQ3OZ0A0VYVU59</lei>
        <title>NATERA INC</title>
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          <isin value="US6323071042"/>
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        <balance>117200.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>UNIQURE N.V.</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>AFFERENT PHARMA</name>
        <lei>N/A</lei>
        <title>AFFERENT PHARMACEUTICALS INC SER C PC PP</title>
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        <assetCat>EP</assetCat>
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      <invstOrSec>
        <name>REGENERON PHARMACEUTICALS INC</name>
        <lei>549300RCBFWIRX3HYQ56</lei>
        <title>REGENERON PHARMACEUTICALS INC</title>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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        <name>VIRIDIAN THERAPEUTICS INC</name>
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        <assetCat>EC</assetCat>
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        <name>MADRIGAL PHARMACEUTICALS INC</name>
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        <name>TENAX THERAPEUTICS INC</name>
        <lei>549300J03O6B1IJ2B606</lei>
        <title>TENAX THERAPEUTICS INC</title>
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        <name>UCB SA</name>
        <lei>2138008J191VLSGY5A09</lei>
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        <cusip>N/A</cusip>
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        <invCountry>BE</invCountry>
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        <name>VERTEX PHARMACEUTICALS INC</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC</title>
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        <name>VIKING THERAPEUTICS INC</name>
        <lei>529900IVC72YPFA25M37</lei>
        <title>VIKING THERAPEUTICS INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>XENON PHARMACEUTICALS INC</name>
        <lei>549300XV44Q9Z1MIPQ03</lei>
        <title>XENON PHARMACEUTICALS INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>CA</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>SPYRE THERAPEUTICS INC</name>
        <lei>52990017AIJPRH3HQH40</lei>
        <title>SPYRE THERAPEUTICS INC</title>
        <cusip>00773J202</cusip>
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        <balance>857347.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>MODERNA INC</name>
        <lei>549300EI6OKH5K5Q2G38</lei>
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        <cusip>60770K107</cusip>
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          <isin value="US60770K1079"/>
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        <balance>640800.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ARGENX SE</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
        <title>ARGENX SE SPONSORED ADR</title>
        <cusip>04016X101</cusip>
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          <isin value="US04016X1019"/>
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        <balance>77200.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ROIVANT SCIENCES LTD</name>
        <lei>549300DL466NY5J6U724</lei>
        <title>ROIVANT SCIENCES LTD</title>
        <cusip>N/A</cusip>
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          <isin value="BMG762791017"/>
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        <balance>776700.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>INFLARX NV</name>
        <lei>391200VC4LWGA9FR8550</lei>
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        <cusip>N/A</cusip>
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          <isin value="NL0012661870"/>
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        <balance>3196071.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>X4 PHARMACEUTICALS INC</name>
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          <isin value="US98420X2027"/>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SOLID BIOSCIENCES INC</name>
        <lei>N/A</lei>
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          <isin value="US83422E2046"/>
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        <balance>677565.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>KINIKSA PHARMACEUTICALS INTERNATIONAL PLC</name>
        <lei>N/A</lei>
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        <cusip>N/A</cusip>
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          <isin value="GB00BRXB0C07"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ARCUS BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>ARCUS BIOSCIENCES INC</title>
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          <isin value="US03969F1093"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>COGENT BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>COGENT BIOSCIENCES INC</title>
        <cusip>19240Q201</cusip>
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          <isin value="US19240Q2012"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SCHOLAR ROCK HOLDING CORP</name>
        <lei>549300Z1FLPGL4OWJ459</lei>
        <title>SCHOLAR ROCK HOLDING CORP</title>
        <cusip>80706P103</cusip>
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          <isin value="US80706P1030"/>
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        <balance>118168.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>DIANTHUS THERAPEUTICS INC</name>
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        <title>DIANTHUS THERAPEUTICS INC</title>
        <cusip>252828108</cusip>
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          <isin value="US2528281080"/>
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        <balance>730062.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>TECTONIC THERAPEUTIC INC</name>
        <lei>N/A</lei>
        <title>TECTONIC THERAPEUTIC INC</title>
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          <isin value="US8789721086"/>
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        <balance>120995.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>KODIAK SCIENCES INC</name>
        <lei>254900IXI5NI8C9OQE24</lei>
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        <cusip>50015M109</cusip>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>REVOLUTION MEDICINES INC</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>REVOLUTION MEDICINES INC</title>
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        <balance>352200.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>STOKE THERAPEUTICS INC</name>
        <lei>549300RD25SS2DIJHJ67</lei>
        <title>STOKE THERAPEUTICS INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>BRIDGEBIO PHARMA INC</name>
        <lei>54930028YG89VTY2J114</lei>
        <title>BRIDGEBIO PHARMA INC</title>
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        <balance>46900.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>MIRUM PHARMACEUTICALS INC</name>
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        <title>MIRUM PHARMACEUTICALS INC</title>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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        <name>ENLIVEN THERAPEUTICS INC</name>
        <lei>N/A</lei>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>DEFINIUM THERAPEUTICS INC</name>
        <lei>529900UG3DGE202N5D44</lei>
        <title>DEFINIUM THERAPEUTICS INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>CA</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>VAXCYTE INC</name>
        <lei>254900M7NMHTGASX8D95</lei>
        <title>VAXCYTE INC</title>
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        <balance>801529.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>VOR BIOPHARMA INC</name>
        <lei>N/A</lei>
        <title>VOR BIOPHARMA INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>INVENTIVA SA</name>
        <lei>969500I9Y690B3FZW590</lei>
        <title>INVENTIVA SA UNSPON ADR</title>
        <cusip>46124U107</cusip>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>RELAY THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RELAY THERAPEUTICS INC</title>
        <cusip>75943R102</cusip>
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        <balance>1850700.00000000</balance>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>ANNEXON INC</name>
        <lei>N/A</lei>
        <title>ANNEXON INC</title>
        <cusip>03589W102</cusip>
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        <balance>1661500.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>DISC MEDICINE INC</name>
        <lei>N/A</lei>
        <title>DISC MEDICINE INC</title>
        <cusip>254604101</cusip>
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          <isin value="US2546041011"/>
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        <balance>80922.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6230994.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KYMERA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KYMERA THERAPEUTICS INC</title>
        <cusip>501575104</cusip>
        <identifiers>
          <isin value="US5015751044"/>
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        <balance>231700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23957780.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>SILENCE THERAPEUTICS PLC</name>
        <lei>213800SSURRJBX85SQ91</lei>
        <title>SILENCE THERAPEUTICS PLC ADR</title>
        <cusip>82686Q101</cusip>
        <identifiers>
          <isin value="US82686Q1013"/>
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        <balance>482088.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5057103.12000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>DYNE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>DYNE THERAPEUTICS INC</title>
        <cusip>26818M108</cusip>
        <identifiers>
          <isin value="US26818M1080"/>
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        <balance>482000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>12136760.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>PRAXIS PRECISION MEDICINES INC.</name>
        <lei>N/A</lei>
        <title>PRAXIS PRECISION MEDICINES INC</title>
        <cusip>74006W207</cusip>
        <identifiers>
          <isin value="US74006W2070"/>
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        <balance>74200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>22840986.00000000</valUSD>
        <pctVal>1.038354701581</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TARSUS PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>TARSUS PHARMACEUTICALS INC</title>
        <cusip>87650L103</cusip>
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          <isin value="US87650L1035"/>
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        <balance>110000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6494400.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>DAMORA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>DAMORA THERAPEUTICS INC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="KYG2646Y1044"/>
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        <balance>298142.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8643136.58000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <loanByFundCondition isLoanByFund="Y" loanVal="6008061.54000000"/>
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      </invstOrSec>
      <invstOrSec>
        <name>OLEMA PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>OLEMA PHARMACEUTICALS INC</title>
        <cusip>68062P106</cusip>
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          <isin value="US68062P1066"/>
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        <balance>777200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8898940.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>EDGEWISE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>EDGEWISE THERAPEUTICS INC</title>
        <cusip>28036F105</cusip>
        <identifiers>
          <isin value="US28036F1057"/>
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        <balance>144500.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5553135.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TYRA BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>TYRA BIOSCIENCES INC</title>
        <cusip>90240B106</cusip>
        <identifiers>
          <isin value="US90240B1061"/>
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        <balance>354200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>11291896.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>BRIGHT PEAK THERAPEUTICS INC.</name>
        <lei>N/A</lei>
        <title>BRIGHT PEAK THERAPEUTICS SER B PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="HFH266000"/>
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        <balance>1920122.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2227341.52000000</valUSD>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>JADE BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>JADE BIOSCIENCES INC</title>
        <cusip>008064206</cusip>
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          <isin value="US0080642061"/>
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        <balance>698671.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>JANUX THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>JANUX THERAPEUTICS INC</title>
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          <isin value="US47103J1051"/>
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        <curCd>USD</curCd>
        <valUSD>4860240.45000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>T-KNIFE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>T-KNIFE THERAPEUTICS INC SER B PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HHE278000"/>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>WUGEN INC</name>
        <lei>N/A</lei>
        <title>WUGEN INC SER B PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HHE329000"/>
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        <balance>580277.00000000</balance>
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        <curCd>USD</curCd>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>TREELINE BIOSCIENCES</name>
        <lei>N/A</lei>
        <title>TREELINE BIOSCIENCES SERIES A PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HIB405000"/>
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        <curCd>USD</curCd>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>CLIMB BIO INC</name>
        <lei>N/A</lei>
        <title>CLIMB BIO INC</title>
        <cusip>28658R106</cusip>
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          <isin value="US28658R1068"/>
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        <curCd>USD</curCd>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>SONOMA BIOTHERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SONOMA BIOTHERAPEUTICS INC SER B PFD PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HIE257000"/>
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      <invstOrSec>
        <name>SONOMA BIOTHERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SONOMA BIOTHERAPEUTICS INC SER B1 PFD PP</title>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>AMYLYX PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>AMYLYX PHARMACEUTICALS INC</title>
        <cusip>03237H101</cusip>
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        <assetCat>EC</assetCat>
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      <invstOrSec>
        <name>LIFEMINE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>LIFEMINE THERAPEUTICS INC SER C PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="IHD504000"/>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>NEWAMSTERDAM PHARMA COMPANY NV</name>
        <lei>984500B6549TF6E14D36</lei>
        <title>NEWAMSTERDAM PHARMA COMPANY NV</title>
        <cusip>N/A</cusip>
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        <invCountry>NL</invCountry>
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        <fairValLevel>1</fairValLevel>
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      </invstOrSec>
      <invstOrSec>
        <name>STRUCTURE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>STRUCTURE THERAPEUTICS INC ADR</title>
        <cusip>86366E106</cusip>
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          <isin value="US86366E1064"/>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MINERALYS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>MINERALYS THERAPEUTICS INC</title>
        <cusip>603170101</cusip>
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          <isin value="US6031701013"/>
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        <balance>331100.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>8449672.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ENLIVEN THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ENLIVEN THERAPEUTICS INC CVR (NON-TRADABLE)</title>
        <cusip>N/A</cusip>
        <identifiers>
          <ticker value="2226681D"/>
        </identifiers>
        <balance>739725.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7.40000000</valUSD>
        <pctVal>0.000000336405</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KARTOS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS INC SERIES C PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="JXD843000"/>
        </identifiers>
        <balance>530692.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4367595.16000000</valUSD>
        <pctVal>0.198551541031</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CG ONCOLOGY INC</name>
        <lei>N/A</lei>
        <title>CG ONCOLOGY INC</title>
        <cusip>156944100</cusip>
        <identifiers>
          <isin value="US1569441009"/>
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        <balance>157700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>11226663.00000000</valUSD>
        <pctVal>0.510365809475</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ENLIVEN THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ENLIVEN THERAPEUTICS INC PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="KGD809000"/>
        </identifiers>
        <balance>73200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4012092.00000000</valUSD>
        <pctVal>0.182390313245</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CONTINEUM THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CONTINEUM THERAPEUTICS INC CL A</title>
        <cusip>21217B100</cusip>
        <identifiers>
          <isin value="US21217B1008"/>
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        <balance>224900.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3483701.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>MBX BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>MBX BIOSCIENCES INC</title>
        <cusip>55287L101</cusip>
        <identifiers>
          <isin value="US55287L1017"/>
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        <balance>817600.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>53904368.00000000</valUSD>
        <pctVal>2.450500777355</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ENDEAVOR BIOMEDICINES INC</name>
        <lei>N/A</lei>
        <title>ENDEAVOR BIOMEDICINES INC SERIES C PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="KHI911000"/>
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        <balance>526643.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3433712.36000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>BRIGHT PEAK THERAPEUTICS INC.</name>
        <lei>N/A</lei>
        <title>BRIGHT PEAK THERAPEUTICS SER C PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="KIK660000"/>
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        <balance>873604.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>777507.56000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>WUGEN INC</name>
        <lei>N/A</lei>
        <title>WUGEN INC CONV 0% 12/31/2199 P/P</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="KKY969000"/>
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        <balance>831313.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>863900.47000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2199-12-31</maturityDt>
          <couponKind>Variable</couponKind>
          <annualizedRt>0.00000000</annualizedRt>
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          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
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          <isMandatoryConvrtbl>Y</isMandatoryConvrtbl>
          <isContngtConvrtbl>Y</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>WUGEN INC</name>
              <title>WUGEN INC</title>
              <curCd>USD</curCd>
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                <other otherDesc="Internal" value="HFD394000"/>
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          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1.50696000" curCd="USD"/>
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          <delta>XXXX</delta>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ALUMIS INC</name>
        <lei>N/A</lei>
        <title>ALUMIS INC</title>
        <cusip>022307102</cusip>
        <identifiers>
          <isin value="US0223071020"/>
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        <balance>946500.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>26738625.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>CARDURION PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>CARDURION PHARMACEUTICALS INC SER B PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="KMC429000"/>
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        <balance>331596.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1900045.08000000</valUSD>
        <pctVal>0.086376338658</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ZENAS BIOPHARMA INC</name>
        <lei>N/A</lei>
        <title>ZENAS BIOPHARMA INC</title>
        <cusip>98937L105</cusip>
        <identifiers>
          <isin value="US98937L1052"/>
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        <balance>491724.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>15459802.56000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>UPSTREAM BIO INC</name>
        <lei>N/A</lei>
        <title>UPSTREAM BIO INC</title>
        <cusip>91678A107</cusip>
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          <isin value="US91678A1079"/>
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        <balance>691003.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4360228.93000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CRESCENT BIOPHARMA INC</name>
        <lei>549300TZ84FFU2J2J459</lei>
        <title>CRESCENT BIOPHARMA INC PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Bloomberg" value="EQ0000000096770470"/>
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        <balance>98300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1422401.00000000</valUSD>
        <pctVal>0.064662566050</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>MENTARI THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>MENTARI THERAPEUTICS INC SER A PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="LQE027000"/>
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        <balance>1457407.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>4343072.86000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>ZENAS BIOPHARMA INC</name>
        <lei>N/A</lei>
        <title>ZENAS BIOPHARMA INC PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="LSC975000"/>
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        <balance>86234.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2711196.96000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>MAPLIGHT THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>MAPLIGHT THERAPEUTICS INC</title>
        <cusip>56565P103</cusip>
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          <isin value="US56565P1030"/>
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        <balance>202900.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2641758.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>AVALYN PHARMA INC</name>
        <lei>N/A</lei>
        <title>AVALYN PHARMA INC</title>
        <cusip>05348Y105</cusip>
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          <isin value="US05348Y1055"/>
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        <balance>162100.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>4666859.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>RALLYBIO CORP</name>
        <lei>254900OR8EZO4FXWJY12</lei>
        <title>AVENZO THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MGV271000"/>
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        <balance>2879204.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>3771757.24000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>KARTOS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPUTIC, INC. CONV 3.6% 03/04/2026 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MGX116000"/>
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        <balance>165790.96000000</balance>
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        <curCd>USD</curCd>
        <valUSD>230300.22000000</valUSD>
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        <assetCat>DBT</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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              <title>KARTOS THERAPEUTICS INC</title>
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      <invstOrSec>
        <name>FIRST TRACKS BIOTHERAPEUTICS INC</name>
        <lei>529900CGIGKN4R5RO925</lei>
        <title>FIRST TRACKS BIOTHERAPEUTICS INC</title>
        <cusip>337185102</cusip>
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          <isin value="US3371851029"/>
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        <balance>341150.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>15024246.00000000</valUSD>
        <pctVal>0.683004510917</pctVal>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>CYCLERION THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KORSANA BIOSCIENCES FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MJJ384000"/>
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        <balance>88900.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>276479.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>HEMAB THERAPEUTICS HOLDINGS INC</name>
        <lei>N/A</lei>
        <title>HEMAB THERAPEUTICS HOLDINGS INC</title>
        <cusip>423494103</cusip>
        <identifiers>
          <isin value="US4234941031"/>
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        <balance>186700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8877585.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isNonCashCollateral>N</isNonCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>CELLCENTRIC LTD</name>
        <lei>N/A</lei>
        <title>CELLCENTRIC LTD SER D PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MML434000"/>
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        <balance>662801.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3141676.74000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>CITY THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CITY THERAPEUTICS INC SER B PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MQW632000"/>
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        <balance>43200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>630720.00000000</valUSD>
        <pctVal>0.028672627240</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>INMED PHARMACEUTICALS INC</name>
        <lei>549300VA5DNHEJGHG397</lei>
        <title>MENTARI THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MQW790000"/>
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        <balance>491700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1465266.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH ADJUSTMENT ESCROW LINE PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA089000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>21924.00000000</valUSD>
        <pctVal>0.000996668378</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH SHAREHOLDER REPRESENTATIVE ESCROW LINE PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA090000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>126.00000000</valUSD>
        <pctVal>0.000005727979</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 1) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA091000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>444087.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 4) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA092000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>349965.00000000</valUSD>
        <pctVal>0.015909462189</pctVal>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 2) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA093000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>675045.00000000</valUSD>
        <pctVal>0.030687648489</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 3) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA094000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>301329.00000000</valUSD>
        <pctVal>0.013698462223</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 5) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA095000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>58716.00000000</valUSD>
        <pctVal>0.002669238300</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 6) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA096000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>185472.00000000</valUSD>
        <pctVal>0.008431585362</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 7) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA097000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>179865.00000000</valUSD>
        <pctVal>0.008176690288</pctVal>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 8) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA098000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>29358.00000000</valUSD>
        <pctVal>0.001334619150</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 9) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA099000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>29358.00000000</valUSD>
        <pctVal>0.001334619150</pctVal>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 10) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA100000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13923.00000000</valUSD>
        <pctVal>0.000632941700</pctVal>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 11) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA101000"/>
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        <balance>6300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13230.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>KARTOS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS INC CONV 3.6% 05/29/2027 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MTV967000"/>
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        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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            <dbtSecRefInstrument>
              <name>KARTOS THERAPEUTICS INC</name>
              <title>KARTOS THERAPEUTICS INC</title>
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      <invstOrSec>
        <name>BRIGHT PEAK THERAPEUTICS INC.</name>
        <lei>N/A</lei>
        <title>BRIGHT PEAK THERAPEUTICS INC CONV 8% 02/28/2027 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUD050000"/>
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          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>BRIGHT PEAK THERAPEUTICS INC.</name>
              <title>BRIGHT PEAK THERAPEUTICS INC PP</title>
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          <currencyInfos>
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      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS ADJUSTMENT ESCROW PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG626000"/>
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        <balance>1500060.00000000</balance>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS SHAREHOLDER REPRESENTATIVE ESCROW PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG631000"/>
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        <balance>1500060.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>15.00000000</valUSD>
        <pctVal>0.000000681902</pctVal>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS CVR (MILESTONE 1) PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG647000"/>
        </identifiers>
        <balance>1500060.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>105004.20000000</valUSD>
        <pctVal>0.004773506921</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS CVR (MILESTONE 2) PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG648000"/>
        </identifiers>
        <balance>1500060.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>60002.40000000</valUSD>
        <pctVal>0.002727718240</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MEDICINES INC</name>
        <lei>N/A</lei>
        <title>PARABILIS MEDICINES INC (180 DAY LOCKUP)</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MWG258000"/>
        </identifiers>
        <balance>529149.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>17980483.02000000</valUSD>
        <pctVal>0.817395495996</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KARTOS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS INC CONV 3.78% 07/10/2027 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MYB098000"/>
        </identifiers>
        <balance>60792.36000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>84148.78000000</valUSD>
        <pctVal>0.003825416352</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2027-07-10</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>0.03780000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>Y</isMandatoryConvrtbl>
          <isContngtConvrtbl>Y</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>KARTOS THERAPEUTICS INC</name>
              <title>KARTOS THERAPEUTICS INC</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal" value="JTD982000"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1000.00000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ADVANCELL PTY LTD</name>
        <lei>N/A</lei>
        <title>ADVANCELL INC SER D PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MYB470000"/>
        </identifiers>
        <balance>699784.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1962054.38000000</valUSD>
        <pctVal>0.089195290878</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>AU</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ADVANCELL PTY LTD</name>
        <lei>N/A</lei>
        <title>ADVANCELL CONV 0% 12/31/2199 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MYB471000"/>
        </identifiers>
        <balance>981027.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>981027.00000000</valUSD>
        <pctVal>0.044597636802</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>AU</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2199-12-31</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>0.00000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>Y</isMandatoryConvrtbl>
          <isContngtConvrtbl>Y</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>ADVANCELL PTY LTD</name>
              <title>ADVANCELL PTY LTD</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Bloomberg ID" value="EQ0000000092101466"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1000.00000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NEXTCURE INC</name>
        <lei>549300Y5PR6RJR1STI24</lei>
        <title>AVERE THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MYJ149000"/>
        </identifiers>
        <balance>195200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2699616.00000000</valUSD>
        <pctVal>0.122724954433</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>LB PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>LB PHARMACEUTICALS INC PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="NAG047000"/>
        </identifiers>
        <balance>14800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>533865.60000000</valUSD>
        <pctVal>0.024269611468</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SYNLOGIC INC</name>
        <lei>5493007C6UCNXL4HOI66</lei>
        <title>CALDERA THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="NAG072000"/>
        </identifiers>
        <balance>1202164.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4151192.51000000</valUSD>
        <pctVal>0.188713843611</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KARTOS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KARTOS THERAPEUTICS INC CONV 3.78% 07/31/2027 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="NAI633000"/>
        </identifiers>
        <balance>38683.48000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>53518.59000000</valUSD>
        <pctVal>0.002432963250</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2027-07-31</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>0.03780000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>Y</isMandatoryConvrtbl>
          <isContngtConvrtbl>Y</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>KARTOS THERAPEUTICS INC</name>
              <title>KARTOS THERAPEUTICS INC</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Internal" value="JTD982000"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1000.00000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="As of March 2025, monthly returns presented in Item B.5.a. have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-08-30</ncom:dateSigned>
      <ncom:nameOfApplicant>Stacie M. Smith</ncom:nameOfApplicant>
      <ncom:signature>Stacie M. Smith</ncom:signature>
      <ncom:signerName>Stacie M. Smith</ncom:signerName>
      <ncom:title>President and Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
