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        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>CENCORA INC</name>
        <lei>AI8GXW8LG5WK7E9UD086</lei>
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        <cusip>03073E105</cusip>
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          <isin value="US03073E1055"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ASCENDIS PHARMA A/S</name>
        <lei>549300B66JN3W3J8GH73</lei>
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        <cusip>N/A</cusip>
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          <isin value="DK0060615755"/>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DK</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>AXSOME THERAPEUTICS INC</name>
        <lei>549300EXGR0XLRJEIB95</lei>
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          <isin value="US05464T1043"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BIOGEN INC</name>
        <lei>W8J5WZB5IY3K0NDQT671</lei>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BOSTON SCIENTIFIC CORP</name>
        <lei>Y6ZDD9FP4P8JSSJMW954</lei>
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          <isin value="US1011371077"/>
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        <balance>820000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BRUKER CORP</name>
        <lei>LEBZ6VLQ6I8XB1NHVY15</lei>
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          <isin value="US1167941087"/>
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        <balance>456516.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CVS HEALTH CORP</name>
        <lei>549300EJG376EN5NQE29</lei>
        <title>CVS HEALTH CORP</title>
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          <isin value="US1266501006"/>
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        <balance>385000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CYTOMX THERAPEUTICS INC</name>
        <lei>5493004VW2FW0QLL3345</lei>
        <title>CYTOMX THERAPEUTICS INC</title>
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          <isin value="US23284F1057"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>DANAHER CORP</name>
        <lei>S4BKK9OTCEWQ3YHPFM11</lei>
        <title>DANAHER CORP</title>
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          <isin value="US2358511028"/>
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        <balance>1080000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>EDWARDS LIFESCIENCES CORP</name>
        <lei>YA13X31F3V31L8TMPR58</lei>
        <title>EDWARDS LIFESCIENCES CORP</title>
        <cusip>28176E108</cusip>
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          <isin value="US28176E1082"/>
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        <balance>150000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>12910500.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Fidelity Revere Street Trust</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Cash Central Fund</title>
        <cusip>31635A105</cusip>
        <identifiers>
          <isin value="US31635A1051"/>
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        <balance>7129121.18000000</balance>
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        <curCd>USD</curCd>
        <valUSD>7130547.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>Fidelity Revere Street Trust</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Securities Lending Cash Central Fund</title>
        <cusip>31635A303</cusip>
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          <isin value="US31635A3032"/>
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        <balance>79331898.99800000</balance>
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        <curCd>USD</curCd>
        <valUSD>79339832.19000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <cashCollateralCondition cashCollateralVal="79339832.19000000" isCashCollateral="Y"/>
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      <invstOrSec>
        <name>GILEAD SCIENCES INC</name>
        <lei>549300WTZWR07K8MNV44</lei>
        <title>GILEAD SCIENCES INC</title>
        <cusip>375558103</cusip>
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          <isin value="US3755581036"/>
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        <balance>300000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>39063000.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>CRESCENT BIOPHARMA INC</name>
        <lei>549300TZ84FFU2J2J459</lei>
        <title>CRESCENT BIOPHARMA INC</title>
        <cusip>N/A</cusip>
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          <isin value="KYG2545C1042"/>
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        <balance>149413.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>JAZZ PHARMACEUTICALS PLC</name>
        <lei>635400GAUMJCLEZRRV50</lei>
        <title>JAZZ PHARMA PLC</title>
        <cusip>N/A</cusip>
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        <balance>128000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ILLUMINA INC</name>
        <lei>SQ95QG8SR5Q56LSNF682</lei>
        <title>ILLUMINA INC</title>
        <cusip>452327109</cusip>
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          <isin value="US4523271090"/>
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        <balance>138000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>28303800.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>INSMED INC</name>
        <lei>529900Q55QAG41CCAC11</lei>
        <title>INSMED INC</title>
        <cusip>457669307</cusip>
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        <balance>208000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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      <invstOrSec>
        <name>INTUITIVE SURGICAL INC</name>
        <lei>54930052SRG011710797</lei>
        <title>INTUITIVE SURGICAL INC</title>
        <cusip>46120E602</cusip>
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        <balance>14000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>JOHNSON and JOHNSON</name>
        <lei>549300G0CFPGEF6X2043</lei>
        <title>JOHNSON and JOHNSON</title>
        <cusip>478160104</cusip>
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          <isin value="US4781601046"/>
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        <balance>460000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>117921000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ELI LILLY and CO</name>
        <lei>FRDRIPF3EKNDJ2CQJL29</lei>
        <title>ELI LILLY and CO</title>
        <cusip>532457108</cusip>
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          <isin value="US5324571083"/>
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        <balance>208000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>238958720.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MERCK and CO INC</name>
        <lei>4YV9Y5M8S0BRK1RP0397</lei>
        <title>MERCK and CO INC NEW</title>
        <cusip>58933Y105</cusip>
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        <balance>500000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>65100000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>NATERA INC</name>
        <lei>529900CQ3OZ0A0VYVU59</lei>
        <title>NATERA INC</title>
        <cusip>632307104</cusip>
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        <balance>192290.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>51487570.40000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>OCULAR THERAPEUTIX INC</name>
        <lei>529900ABAWFXOHSIHG03</lei>
        <title>OCULAR THERAPEUTIX INC</title>
        <cusip>67576A100</cusip>
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        <balance>277371.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2266121.07000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>REPLIGEN CORP</name>
        <lei>54930006QJ0T5AUO1E71</lei>
        <title>REPLIGEN</title>
        <cusip>759916109</cusip>
        <identifiers>
          <isin value="US7599161095"/>
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        <balance>270000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>38072700.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>TRAVERE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>TRAVERE THERAPEUTICS INC</title>
        <cusip>89422G107</cusip>
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          <isin value="US89422G1076"/>
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        <balance>208000.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TWIST BIOSCIENCE CORP</name>
        <lei>549300T23BL59LCOH584</lei>
        <title>TWIST BIOSCIENCE CORP</title>
        <cusip>90184D100</cusip>
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          <isin value="US90184D1000"/>
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        <balance>135000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>12359250.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>VIRIDIAN THERAPEUTICS INC</name>
        <lei>549300C775BNYF550E70</lei>
        <title>VIRIDIAN THERAPEUTICS INC</title>
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          <isin value="US92790C1045"/>
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        <balance>760000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SARTORIUS STEDIM BIOTECH</name>
        <lei>52990006IVXY7GCSSR39</lei>
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        <cusip>N/A</cusip>
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          <isin value="FR0013154002"/>
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        <assetCat>EC</assetCat>
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        <invCountry>FR</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>THERMO FISHER SCIENTIFIC INC</name>
        <lei>HCHV7422L5HDJZCRFL38</lei>
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          <isin value="US8835561023"/>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>UNITEDHEALTH GROUP INC</name>
        <lei>549300GHBMY8T5GXDE41</lei>
        <title>UNITEDHEALTH GROUP INC</title>
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          <isin value="US91324P1021"/>
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        <balance>314000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>UCB SA</name>
        <lei>2138008J191VLSGY5A09</lei>
        <title>UCB SA</title>
        <cusip>N/A</cusip>
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          <isin value="BE0003739530"/>
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        <balance>160000.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>BE</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>VERACYTE INC</name>
        <lei>529900ESWZRHXOW27Z37</lei>
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          <isin value="US92337F1075"/>
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        <balance>600000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>VIKING THERAPEUTICS INC</name>
        <lei>529900IVC72YPFA25M37</lei>
        <title>VIKING THERAPEUTICS INC</title>
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          <isin value="US92686J1060"/>
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        <balance>280000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>WATERS CORP</name>
        <lei>5T547R1474YC9HOD8Q74</lei>
        <title>WATERS CORP</title>
        <cusip>941848103</cusip>
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          <isin value="US9418481035"/>
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        <balance>118000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>WEST PHARMACEUTICAL SVCS INC</name>
        <lei>5493007NKRGM1RJQ1P16</lei>
        <title>WEST PHARMACEUTICAL SVCS INC</title>
        <cusip>955306105</cusip>
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        <balance>188400.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>XENON PHARMACEUTICALS INC</name>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>CA</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BEONE MEDICINES LTD</name>
        <lei>549300JFUK6FRD5MH739</lei>
        <title>BEONE MEDICINES LTD ADR</title>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>CH</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>10X GENOMICS INC</name>
        <lei>5493003Z6741WNLG7H43</lei>
        <title>10X GENOMICS INC</title>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SPYRE THERAPEUTICS INC</name>
        <lei>52990017AIJPRH3HQH40</lei>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MODERNA INC</name>
        <lei>549300EI6OKH5K5Q2G38</lei>
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        <fairValLevel>1</fairValLevel>
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        <name>IRHYTHM TECHNOLOGIES INC</name>
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        <name>ARGENX SE</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
        <title>ARGENX SE SPONSORED ADR</title>
        <cusip>04016X101</cusip>
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        <invCountry>NL</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>ROIVANT SCIENCES LTD</name>
        <lei>549300DL466NY5J6U724</lei>
        <title>ROIVANT SCIENCES LTD</title>
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        <balance>640000.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>BM</invCountry>

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      <invstOrSec>
        <name>KINIKSA PHARMACEUTICALS INTERNATIONAL PLC</name>
        <lei>N/A</lei>
        <title>KINIKSA PHARMACEUTICALS INTERNATIONAL PLC</title>
        <cusip>N/A</cusip>
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        <assetCat>EC</assetCat>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>COGENT BIOSCIENCES INC</name>
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        <title>COGENT BIOSCIENCES INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>SCHOLAR ROCK HOLDING CORP</name>
        <lei>549300Z1FLPGL4OWJ459</lei>
        <title>SCHOLAR ROCK HOLDING CORP</title>
        <cusip>80706P103</cusip>
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        <balance>218000.00000000</balance>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>DIANTHUS THERAPEUTICS INC</name>
        <lei>549300Z3N6ODPCOFC890</lei>
        <title>DIANTHUS THERAPEUTICS INC</title>
        <cusip>252828108</cusip>
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        <balance>163257.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>GUARDANT HEALTH INC</name>
        <lei>254900M8C3E5VC8BR186</lei>
        <title>GUARDANT HEALTH INC</title>
        <cusip>40131M109</cusip>
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          <isin value="US40131M1099"/>
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        <balance>285000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>46167150.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>CYCLERION THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CYCLERION THERAPEUTICS INC</title>
        <cusip>23255M204</cusip>
        <identifiers>
          <isin value="US23255M2044"/>
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        <balance>1500.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5160.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="4816.00000000"/>
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      </invstOrSec>
      <invstOrSec>
        <name>TREVI THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>TREVI THERAPEUTICS INC</title>
        <cusip>89532M101</cusip>
        <identifiers>
          <isin value="US89532M1018"/>
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        <balance>480000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8760000.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>REVOLUTION MEDICINES INC</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>REVOLUTION MEDICINES INC</title>
        <cusip>76155X100</cusip>
        <identifiers>
          <isin value="US76155X1000"/>
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        <balance>240300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>45063459.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>STOKE THERAPEUTICS INC</name>
        <lei>549300RD25SS2DIJHJ67</lei>
        <title>STOKE THERAPEUTICS INC</title>
        <cusip>86150R107</cusip>
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          <isin value="US86150R1077"/>
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        <balance>330000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9523800.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>MIRUM PHARMACEUTICALS INC</name>
        <lei>254900YZKR40F7F27K81</lei>
        <title>MIRUM PHARMACEUTICALS INC</title>
        <cusip>604749101</cusip>
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          <isin value="US6047491013"/>
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        <balance>128000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13561600.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="2585180.00000000"/>
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      </invstOrSec>
      <invstOrSec>
        <name>ENLIVEN THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ENLIVEN THERAPEUTICS INC</title>
        <cusip>29337E102</cusip>
        <identifiers>
          <isin value="US29337E1029"/>
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        <balance>670000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>36722700.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="19676790.00000000"/>
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      <invstOrSec>
        <name>LEGEND BIOTECH CORP</name>
        <lei>254900EIUFZTW136H859</lei>
        <title>LEGEND BIOTECH CORP SPON ADR</title>
        <cusip>52490G102</cusip>
        <identifiers>
          <isin value="US52490G1022"/>
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        <balance>1019556.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>VAXCYTE INC</name>
        <lei>254900M7NMHTGASX8D95</lei>
        <title>VAXCYTE INC</title>
        <cusip>92243G108</cusip>
        <identifiers>
          <isin value="US92243G1085"/>
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        <balance>630000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>34070400.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>ROYALTY PHARMA PLC</name>
        <lei>549300FGFN7VOK8BZR03</lei>
        <title>ROYALTY PHARMA PLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="GB00BMVP7Y09"/>
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        <balance>600000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>35058000.00000000</valUSD>
        <pctVal>1.123864140773</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>RELAY THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RELAY THERAPEUTICS INC</title>
        <cusip>75943R102</cusip>
        <identifiers>
          <isin value="US75943R1023"/>
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        <balance>1040000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>19583200.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="11968348.00000000"/>
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      <invstOrSec>
        <name>ANNEXON INC</name>
        <lei>N/A</lei>
        <title>ANNEXON INC</title>
        <cusip>03589W102</cusip>
        <identifiers>
          <isin value="US03589W1027"/>
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        <balance>750000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3821250.00000000</valUSD>
        <pctVal>0.122498883220</pctVal>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>DISC MEDICINE INC</name>
        <lei>N/A</lei>
        <title>DISC MEDICINE INC</title>
        <cusip>254604101</cusip>
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          <isin value="US2546041011"/>
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        <balance>200000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>15400000.00000000</valUSD>
        <pctVal>0.493682120141</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>KYMERA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KYMERA THERAPEUTICS INC</title>
        <cusip>501575104</cusip>
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          <isin value="US5015751044"/>
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        <balance>228000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23575200.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>OUTSET MEDICAL INC</name>
        <lei>N/A</lei>
        <title>OUTSET MEDICAL INC</title>
        <cusip>690145206</cusip>
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          <isin value="US6901452069"/>
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        <balance>800000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3656000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SUMMIT THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SUMMIT THERAPEUTICS INC</title>
        <cusip>86627T108</cusip>
        <identifiers>
          <isin value="US86627T1088"/>
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        <balance>400000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>5208000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>IMMUNOME INC</name>
        <lei>N/A</lei>
        <title>IMMUNOME INC</title>
        <cusip>45257U108</cusip>
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          <isin value="US45257U1088"/>
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        <balance>38378.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>873483.28000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>PRAXIS PRECISION MEDICINES INC.</name>
        <lei>N/A</lei>
        <title>PRAXIS PRECISION MEDICINES INC</title>
        <cusip>74006W207</cusip>
        <identifiers>
          <isin value="US74006W2070"/>
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        <balance>82800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>25488324.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>DAMORA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>DAMORA THERAPEUTICS INC</title>
        <cusip>N/A</cusip>
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          <isin value="KYG2646Y1044"/>
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        <balance>280000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8117200.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>DMED BIOPHARMACEUTICAL CO LTD</name>
        <lei>N/A</lei>
        <title>DMED BIOPHARMACEUTICAL CO LTD SER C PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="GIB636000"/>
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        <balance>205024.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CN</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>VIATRIS INC</name>
        <lei>254900ZZTSW7NL773X71</lei>
        <title>VIATRIS INC</title>
        <cusip>92556V106</cusip>
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          <isin value="US92556V1061"/>
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        <balance>2960000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>51977600.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>OLEMA PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>OLEMA PHARMACEUTICALS INC</title>
        <cusip>68062P106</cusip>
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          <isin value="US68062P1066"/>
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        <balance>820000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>9389000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
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      <invstOrSec>
        <name>PHARVARIS BV</name>
        <lei>9845003BE146D3B75D32</lei>
        <title>PHARVARIS BV</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="NL00150005Y4"/>
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        <balance>400000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>13048000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="2218160.00000000"/>
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      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOCORE HOLDINGS PLC</name>
        <lei>213800IUE3DFS84BVN18</lei>
        <title>IMMUNOCORE HOLDINGS LTD ADR</title>
        <cusip>45258D105</cusip>
        <identifiers>
          <isin value="US45258D1054"/>
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        <balance>260000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>8790600.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="2380224.00000000"/>
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      </invstOrSec>
      <invstOrSec>
        <name>ALIGNMENT HEALTHCARE INC</name>
        <lei>N/A</lei>
        <title>ALIGNMENT HEALTHCARE INC</title>
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          <isin value="US01625V1044"/>
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        <balance>708000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>10513800.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ELEVATEBIO, LLC</name>
        <lei>N/A</lei>
        <title>ELEVATEBIO LLC SER C PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HCJ459000"/>
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        <balance>163300.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>300472.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>EDGEWISE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>EDGEWISE THERAPEUTICS INC</title>
        <cusip>28036F105</cusip>
        <identifiers>
          <isin value="US28036F1057"/>
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        <balance>143000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5495490.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>CARIS LIFE SCIENCES INC</name>
        <lei>549300LX5LO78M5VPY43</lei>
        <title>CARIS LIFE SCIENCES INC</title>
        <cusip>142152107</cusip>
        <identifiers>
          <isin value="US1421521071"/>
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        <balance>933749.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>14631846.83000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TYRA BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>TYRA BIOSCIENCES INC</title>
        <cusip>90240B106</cusip>
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          <isin value="US90240B1061"/>
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        <balance>140000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>4463200.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>PRIVIA HEALTH GROUP INC</name>
        <lei>N/A</lei>
        <title>PRIVIA HEALTH GROUP INC</title>
        <cusip>74276R102</cusip>
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          <isin value="US74276R1023"/>
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        <balance>896700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>21224889.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ALEDADE INC</name>
        <lei>N/A</lei>
        <title>ALEDADE INC SER B1 PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HFE440000"/>
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        <balance>130618.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>JADE BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>JADE BIOSCIENCES INC</title>
        <cusip>008064206</cusip>
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          <isin value="US0080642061"/>
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        <balance>370600.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>LIFESTANCE HEALTH GROUP INC</name>
        <lei>N/A</lei>
        <title>LIFESTANCE HEALTH GROUP INC</title>
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          <isin value="US53228F1012"/>
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        <balance>2500000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>26200000.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ELEMENT BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES INC SER C PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="HHB001000"/>
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        <balance>376690.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>WUGEN INC</name>
        <lei>N/A</lei>
        <title>WUGEN INC SER B PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="HHE329000"/>
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        <balance>300054.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>465083.70000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>CLIMB BIO INC</name>
        <lei>N/A</lei>
        <title>CLIMB BIO INC</title>
        <cusip>28658R106</cusip>
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          <isin value="US28658R1068"/>
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        <balance>214022.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2546861.80000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>FAHEAL THRIVE HOLDINGS LLC</name>
        <lei>N/A</lei>
        <title>FAHEAL THRIVE HOLDINGS LLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="HIF750000"/>
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        <balance>327591.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ASIMOV INC</name>
        <lei>N/A</lei>
        <title>ASIMOV INC SER B PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="IAD374000"/>
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        <balance>67547.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BRIGHTSPRING HEALTH SERVICES INC</name>
        <lei>N/A</lei>
        <title>BRIGHTSPRING HEALTH SERVICES INC</title>
        <cusip>10950A106</cusip>
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          <isin value="US10950A1060"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>AMYLYX PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>AMYLYX PHARMACEUTICALS INC</title>
        <cusip>03237H101</cusip>
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          <isin value="US03237H1014"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>GALVANIZE THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>GALVANIZE THERAPEUTICS SER B PC PERP PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="IIF751000"/>
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        <balance>2552870.00000000</balance>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ALEDADE INC</name>
        <lei>N/A</lei>
        <title>ALEDADE INC SER E1 PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="JBH316000"/>
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        <balance>46526.00000000</balance>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>CLEERLY INC</name>
        <lei>N/A</lei>
        <title>CLEERLY INC SER C PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="JJS547000"/>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>NEWAMSTERDAM PHARMA COMPANY NV</name>
        <lei>984500B6549TF6E14D36</lei>
        <title>NEWAMSTERDAM PHARMA COMPANY NV</title>
        <cusip>N/A</cusip>
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          <isin value="NL00150012L7"/>
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        <assetCat>EC</assetCat>
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        <invCountry>NL</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>STRUCTURE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>STRUCTURE THERAPEUTICS INC ADR</title>
        <cusip>86366E106</cusip>
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          <isin value="US86366E1064"/>
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        <assetCat>EC</assetCat>
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        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MINERALYS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>MINERALYS THERAPEUTICS INC</title>
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          <isin value="US6031701013"/>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>CG ONCOLOGY INC</name>
        <lei>N/A</lei>
        <title>CG ONCOLOGY INC</title>
        <cusip>156944100</cusip>
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          <isin value="US1569441009"/>
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        <balance>228000.00000000</balance>
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        <valUSD>16231320.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MEDICAL MICROINSTRUMENTS INC</name>
        <lei>N/A</lei>
        <title>MEDICAL MICROINSTRUMENTS INC SER C PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="KEQ954000"/>
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        <balance>199633.00000000</balance>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>MEDICAL MICROINSTRUMENTS INC</name>
        <lei>N/A</lei>
        <title>MEDICAL MICROINSTRUMENTS INC WT 02/16/2031 PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="KEQ955000"/>
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        <balance>9982.00000000</balance>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>CONTINEUM THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CONTINEUM THERAPEUTICS INC CL A</title>
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          <isin value="US21217B1008"/>
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        <curCd>USD</curCd>
        <valUSD>4337200.00000000</valUSD>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MBX BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>MBX BIOSCIENCES INC</title>
        <cusip>55287L101</cusip>
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          <isin value="US55287L1017"/>
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        <curCd>USD</curCd>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ENDEAVOR BIOMEDICINES INC</name>
        <lei>N/A</lei>
        <title>ENDEAVOR BIOMEDICINES INC SERIES C PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="KHI911000"/>
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        <curCd>USD</curCd>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>INSIGHTEC LTD</name>
        <lei>N/A</lei>
        <title>INSIGHTEC LTD SER G PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="KKY133000"/>
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        <balance>7391153.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IL</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>WUGEN INC</name>
        <lei>N/A</lei>
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        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="KKY969000"/>
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        <curCd>USD</curCd>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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            <dbtSecRefInstrument>
              <name>WUGEN INC</name>
              <title>WUGEN INC</title>
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          <currencyInfos>
            <currencyInfo convRatio="1.50696000" curCd="USD"/>
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          <delta>XXXX</delta>
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      <invstOrSec>
        <name>ALUMIS INC</name>
        <lei>N/A</lei>
        <title>ALUMIS INC</title>
        <cusip>022307102</cusip>
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          <isin value="US0223071020"/>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ELEMENT BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES INC SER D PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="KLO413000"/>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>ELEMENT BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>ELEMENT BIOSCIENCES INC SER D1 PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="KLO422000"/>
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        <balance>246623.00000000</balance>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ZENAS BIOPHARMA INC</name>
        <lei>N/A</lei>
        <title>ZENAS BIOPHARMA INC</title>
        <cusip>98937L105</cusip>
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          <isin value="US98937L1052"/>
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        <balance>500000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>15720000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>UPSTREAM BIO INC</name>
        <lei>N/A</lei>
        <title>UPSTREAM BIO INC</title>
        <cusip>91678A107</cusip>
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          <isin value="US91678A1079"/>
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        <balance>400000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2524000.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>KESTRA MEDICAL TECHNOLOGIES INC</name>
        <lei>N/A</lei>
        <title>KESTRA MEDICAL TECHNOLOGIES INC</title>
        <cusip>N/A</cusip>
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          <isin value="BMG524411052"/>
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        <balance>471200.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>10757496.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>HEARTFLOW INC</name>
        <lei>N/A</lei>
        <title>HEARTFLOW INC</title>
        <cusip>42238D107</cusip>
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          <isin value="US42238D1072"/>
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        <balance>520000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MANUS BIO INC</name>
        <lei>N/A</lei>
        <title>MANUS BIO INC SER ONE-6 PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="LEH444000"/>
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        <balance>695694.00000000</balance>
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        <assetCat>EP</assetCat>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>GALVANIZE THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>GALVANIZE THERAPEUTICS SER C-1 PC PERP PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="LIK052000"/>
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        <balance>5198598.00000000</balance>
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        <curCd>USD</curCd>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>GALVANIZE THERAPEUTICS</name>
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          <other otherDesc="Internal" value="LIO262000"/>
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        <fairValLevel>3</fairValLevel>
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        <name>SHOULDER INNOVATIONS INC</name>
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        <name>KARDIUM CORP</name>
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        <name>KARDIUM CORP</name>
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      <invstOrSec>
        <name>KARDIUM CORP</name>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>ZENAS BIOPHARMA INC</name>
        <lei>N/A</lei>
        <title>ZENAS BIOPHARMA INC PIPE</title>
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        <curCd>USD</curCd>
        <valUSD>3838792.56000000</valUSD>
        <pctVal>0.123061249987</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SALUDA MEDICAL INC</name>
        <lei>N/A</lei>
        <title>SALUDA MEDICAL INC (2 YEAR LOCK UP) PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="LXA546000"/>
        </identifiers>
        <balance>215913.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="AUD" exchangeRt="1.42116109"/>
        <valUSD>676075.96000000</valUSD>
        <pctVal>0.021673156708</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FREENOME INC</name>
        <lei>N/A</lei>
        <title>FREENOME INC PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="LYC305000"/>
        </identifiers>
        <balance>169200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1886580.00000000</valUSD>
        <pctVal>0.060478624299</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>VERADERMICS INC</name>
        <lei>N/A</lei>
        <title>VERADERMICS INC</title>
        <cusip>922967104</cusip>
        <identifiers>
          <isin value="US9229671048"/>
        </identifiers>
        <balance>60000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6300000.00000000</valUSD>
        <pctVal>0.201960867330</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>RALLYBIO CORP</name>
        <lei>254900OR8EZO4FXWJY12</lei>
        <title>AVENZO THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MGV271000"/>
        </identifiers>
        <balance>1095164.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1434664.84000000</valUSD>
        <pctVal>0.045991453240</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>FIRST TRACKS BIOTHERAPEUTICS INC</name>
        <lei>529900CGIGKN4R5RO925</lei>
        <title>FIRST TRACKS BIOTHERAPEUTICS INC</title>
        <cusip>337185102</cusip>
        <identifiers>
          <isin value="US3371851029"/>
        </identifiers>
        <balance>200000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8808000.00000000</valUSD>
        <pctVal>0.282360526896</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CYCLERION THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KORSANA BIOSCIENCES FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MJJ384000"/>
        </identifiers>
        <balance>138700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>431357.00000000</valUSD>
        <pctVal>0.013828132356</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ALMAR BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>ALMAR BIOSCIENCES INC</title>
        <cusip>010911105</cusip>
        <identifiers>
          <isin value="US0109111056"/>
        </identifiers>
        <balance>160000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4057600.00000000</valUSD>
        <pctVal>0.130075621473</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HEMAB THERAPEUTICS HOLDINGS INC</name>
        <lei>N/A</lei>
        <title>HEMAB THERAPEUTICS HOLDINGS INC</title>
        <cusip>423494103</cusip>
        <identifiers>
          <isin value="US4234941031"/>
        </identifiers>
        <balance>33000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1569150.00000000</valUSD>
        <pctVal>0.050302681741</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="1564395.00000000"/>
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      </invstOrSec>
      <invstOrSec>
        <name>GMR SOLUTIONS INC</name>
        <lei>N/A</lei>
        <title>GMR SOLUTIONS INC</title>
        <cusip>38013D106</cusip>
        <identifiers>
          <isin value="US38013D1063"/>
        </identifiers>
        <balance>282226.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3635070.88000000</valUSD>
        <pctVal>0.116530486941</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CELLCENTRIC LTD</name>
        <lei>N/A</lei>
        <title>CELLCENTRIC LTD SER D PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MML434000"/>
        </identifiers>
        <balance>618437.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2931391.38000000</valUSD>
        <pctVal>0.093972435807</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INMED PHARMACEUTICALS INC</name>
        <lei>549300VA5DNHEJGHG397</lei>
        <title>MENTARI THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MQW790000"/>
        </identifiers>
        <balance>703800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2097324.00000000</valUSD>
        <pctVal>0.067234503827</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH ADJUSTMENT ESCROW LINE PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA089000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>23664.00000000</valUSD>
        <pctVal>0.000758603486</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH SHAREHOLDER REPRESENTATIVE ESCROW LINE PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA090000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>136.00000000</valUSD>
        <pctVal>0.000004359790</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 1) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA091000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>479332.00000000</valUSD>
        <pctVal>0.015366080390</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 4) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA092000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>377740.00000000</valUSD>
        <pctVal>0.012109317146</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 2) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA093000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>728620.00000000</valUSD>
        <pctVal>0.023357575738</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 3) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA094000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>325244.00000000</valUSD>
        <pctVal>0.010426438148</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 5) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA095000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>63376.00000000</valUSD>
        <pctVal>0.002031662210</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 6) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA096000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>200192.00000000</valUSD>
        <pctVal>0.006417611103</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 7) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA097000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>194140.00000000</valUSD>
        <pctVal>0.006223600441</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 8) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA098000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>31688.00000000</valUSD>
        <pctVal>0.001015831105</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 9) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA099000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>31688.00000000</valUSD>
        <pctVal>0.001015831105</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 10) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA100000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>15028.00000000</valUSD>
        <pctVal>0.000481756811</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TUBULIS GMBH</name>
        <lei>391200YI45XXSZ9Z2J67</lei>
        <title>TUBULIS GMBH CVR (MILESTONE 11) 05/21/2036 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MRA101000"/>
        </identifiers>
        <balance>6800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>14280.00000000</valUSD>
        <pctVal>0.000457777965</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS ADJUSTMENT ESCROW PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG626000"/>
        </identifiers>
        <balance>1956465.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>19564.65000000</valUSD>
        <pctVal>0.000627189473</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS SHAREHOLDER REPRESENTATIVE ESCROW PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG631000"/>
        </identifiers>
        <balance>1956465.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>19.56000000</valUSD>
        <pctVal>0.000000627040</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS CVR (MILESTONE 1) PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG647000"/>
        </identifiers>
        <balance>1956465.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>136952.55000000</valUSD>
        <pctVal>0.004390326314</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CANDID THERAPEUTICS</name>
        <lei>N/A</lei>
        <title>CANDID THERAPEUTICS CVR (MILESTONE 2) PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MUG648000"/>
        </identifiers>
        <balance>1956465.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>78258.60000000</valUSD>
        <pctVal>0.002508757893</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PARABILIS MEDICINES INC</name>
        <lei>N/A</lei>
        <title>PARABILIS MEDICINES INC (180 DAY LOCKUP)</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MWG258000"/>
        </identifiers>
        <balance>296640.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>10079827.20000000</valUSD>
        <pctVal>0.323131848230</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ADVANCELL PTY LTD</name>
        <lei>N/A</lei>
        <title>ADVANCELL INC SER D PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MYB470000"/>
        </identifiers>
        <balance>669434.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1876959.05000000</valUSD>
        <pctVal>0.060170202806</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>AU</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ADVANCELL PTY LTD</name>
        <lei>N/A</lei>
        <title>ADVANCELL CONV 0% 12/31/2199 PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MYB471000"/>
        </identifiers>
        <balance>938479.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>938479.00000000</valUSD>
        <pctVal>0.030085084573</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>DBT</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>AU</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <debtSec>
          <maturityDt>2199-12-31</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>0.00000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
          <isMandatoryConvrtbl>Y</isMandatoryConvrtbl>
          <isContngtConvrtbl>Y</isContngtConvrtbl>
          <dbtSecRefInstruments>
            <dbtSecRefInstrument>
              <name>ADVANCELL PTY LTD</name>
              <title>ADVANCELL PTY LTD</title>
              <curCd>USD</curCd>
              <identifiers>
                <other otherDesc="Bloomberg ID" value="EQ0000000092101466"/>
              </identifiers>
            </dbtSecRefInstrument>
          </dbtSecRefInstruments>
          <currencyInfos>
            <currencyInfo convRatio="1000.00000000" curCd="USD"/>
          </currencyInfos>
          <delta>XXXX</delta>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NEXTCURE INC</name>
        <lei>549300Y5PR6RJR1STI24</lei>
        <title>AVERE THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="MYJ149000"/>
        </identifiers>
        <balance>278500.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3851655.00000000</valUSD>
        <pctVal>0.123473584834</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>SYNLOGIC INC</name>
        <lei>5493007C6UCNXL4HOI66</lei>
        <title>CALDERA THERAPEUTICS FWD CMMT PIPE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="NAG072000"/>
        </identifiers>
        <balance>1702100.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5877521.51000000</valUSD>
        <pctVal>0.188417355859</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="As of March 2025, monthly returns presented in Item B.5.a. have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-08-30</ncom:dateSigned>
      <ncom:nameOfApplicant>Stacie M. Smith</ncom:nameOfApplicant>
      <ncom:signature>Stacie M. Smith</ncom:signature>
      <ncom:signerName>Stacie M. Smith</ncom:signerName>
      <ncom:title>President and Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
