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Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Cash Flows From Operating Activities:    
Net loss $ (5,539,543) $ (6,677,587)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 23,688 134,754
Non-cash lease expense 81,258 73,579
Depreciation 12,865 13,683
Amortization of patents 228,107
Gain on forgiveness of PPP Loan and interest (63,094)
Changes in operating assets and liabilities    
Short term receivables (1,449) 50,321
Prepaid expenses 265,957 347,107
Accounts payable 331,148 (170,413)
Unearned grant revenue 2,500,000
Other accrued expenses 502,581 244,887
Operating lease liability (83,549) (77,916)
Accrued interest expense 956,834 1,747,683
Net Cash Used In Operating Activities (1,013,304) (4,085,795)
Cash Flows From Financing Activities:    
Proceeds from issuance of convertible notes payable 2,960,000 3,125,000
Proceeds from issuance of convertible notes payable - related parties 200,000 100,000
Repayment of short-term note payable (248,177) (105,985)
Proceeds from note payable 62,500
Deposit for purchase of Series D-1 Preferred Stock 150,000
Proceeds from exercise of warrants 962,223 418,676
Net Cash Provided By Financing Activities 4,024,046 3,600,191
Effect of exchange rates on cash, cash equivalents, and restricted cash (1,031) (7,871)
Net Increase (Decrease) In Cash, Cash Equivalents, and Restricted Cash 3,009,711 (493,475)
Cash, Cash Equivalents, and Restricted Cash, Beginning of Period 97,231 590,706
Cash, Cash Equivalents, and Restricted Cash, End of Period 3,106,942 97,231
Cash and cash equivalents 682,984 97,231
Restricted cash 2,423,958
Cash and cash Equivalents, restricted cash 3,106,942 97,231
Cash paid during the period for:    
Interest
Income taxes
Non-cash investing and financing activities:    
Purchase of insurance policies financed by short-term note payable 273,347 318,775
Conversion of non-amended 2017 Notes to Series D Preferred Stock 3,541,222
Conversion of amended 2017 Notes and 2020 Notes to Series D-1 Preferred Stock 27,031,858
Conversion of Series D-1 Preferred Stock to Common stock $ 222