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Condensed Consolidated Statements of Cash Flow (Unaudited) (USD $)
9 Months Ended 128 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Cash Flows From Operating Activities      
Net loss $ (10,647,282) $ (15,982,768) $ (116,432,004)
Adjustments to reconcile net loss to net cash used in operating activities      
Depreciation 4,579 5,737 444,378
Amortization of patents 503,340 503,340 6,621,717
Amortization of original issue discount     3,845,721
Amortization of commitment fee     310,866
Amortization of prepaid consultant expense     1,295,226
Amortization of deferred loan costs     2,261,584
Accretion of United States Treasury Bills     (373,295)
Loss on extinguishment of debt       825,867
Loss on exercise of warrants     236,146
Beneficial conversion of convertible interest     55,976
Convertible interest     389,950
Compensation through issuance of stock options 183,028 3,368,950 14,397,729
Compensation through issuance of stock     932,000
Issuance of stock for services 409,250 268,500 9,006,261
Issuance of warrants for services 1,381,329 540,316 6,065,872
Issuance of warrants for contractual obligations     985,010
Gain on sale of equipment       (55,075)
Gain on change in fair value of warrant liability (1,435,898) (1,059,730) (5,580,181)
(Increase) decrease in assets      
Prepaid expenses and other current assets (16,284) (42,415) (16,284)
Increase (decrease) in liabilities      
Accounts payable 179,513 (271,314) 276,970
Accrued expenses 1,512,859 (588,369) 1,824,111
Net cash used in operating activities (7,925,566) (13,257,753) (72,681,455)
Cash Flows From Investing Activities      
Proceeds from sale of fixed assets     180,075
Capital expenditures (15,885) (6,147) (89,920)
Proceeds from sales of investments     37,010,481
Purchases of investments     (36,637,186)
Net cash (used in) provided by investing activities (15,885) (6,147) 463,450
Cash Flows From Financing Activities      
Net proceeds from loans from stockholder     174,000
Proceeds from convertible debt     6,706,795
Net proceeds from sales of preferred stock and warrants     8,908,131
Net proceeds from sales of common stock and warrants 2,077,796 9,486,071 40,101,773
Proceeds from exercises of warrants and stock options   6,504,209 21,078,014
Cash paid to retire convertible debt     (2,385,959)
Cash paid for deferred loan costs     (747,612)
Premium paid on extinguishments of debt     (170,519)
Purchase and retirement of common stock     (48,000)
Net proceeds from sale non-controlling interest in Pure-ific Corporation     443,500
Net cash provided by financing activities 2,077,796 15,990,280 74,060,123
Net change in cash and cash equivalents (5,863,655) 2,726,380 1,842,118
Cash and cash equivalents, at beginning of period 7,705,773 8,086,200  
Cash and cash equivalents, at end of period 1,842,118 10,812,580 1,842,118
Supplemental Disclosure of Noncash Investing and Financing Activities:      
Amount reclassified from warrant liability to equity   $ 485,467