X0306 4 2016-03-29 0 0000315545 PROVECTUS BIOPHARMACEUTICALS, INC. PVCT 0001124261 WACHTER ERIC PHD 7327 OAK RIDGE HWY., SUITE A KNOXVILLE TN 37931 1 1 0 0 Chief Technology Officer Common Stock 2016-03-29 4 O 0 200947 1.00 A 5714183 D Common Stock 2016-03-29 4 O 0 106000 1.00 A 930248 I By 401(k) Plan Common Stock 4867 I By Trust Common Stock Warrants (right to buy) 1.00 2016-03-29 4 O 0 306947 D 2012-11-16 2017-11-16 Common Stock 306947 359719 D Common Stock Warrants (right to buy) 0.85 2016-03-29 4 O 0 306947 A 2016-03-29 2020-06-19 Common Stock 306947 306947 D On March 29, 2016, the reporting person exercised 306,947 warrants pursuant to the Issuer's warrant exchange offer, at a discounted exercise price of $0.50 per share. Under the terms of the warrant exchange offer, holders received, in addition to the common stock acquired upon exercise of their existing warrants, an equal number of new warrants to purchase the same number of shares of the Issuer's common stock at an exercise price of $0.85 per share that will expire June 19, 2020. /s/ Eric Wachter, Ph.D. 2016-03-31