0001209191-23-059755.txt : 20231227 0001209191-23-059755.hdr.sgml : 20231227 20231227104909 ACCESSION NUMBER: 0001209191-23-059755 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20231222 FILED AS OF DATE: 20231227 DATE AS OF CHANGE: 20231227 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: FMR LLC CENTRAL INDEX KEY: 0000315066 ORGANIZATION NAME: STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 001-41608 FILM NUMBER: 231515344 BUSINESS ADDRESS: STREET 1: 245 SUMMER STREET CITY: BOSTON STATE: MA ZIP: 02210 BUSINESS PHONE: 6175706339 MAIL ADDRESS: STREET 1: 245 SUMMER STREET CITY: BOSTON STATE: MA ZIP: 02210 FORMER NAME: FORMER CONFORMED NAME: FMR CORP DATE OF NAME CHANGE: 19920717 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: Structure Therapeutics Inc. CENTRAL INDEX KEY: 0001888886 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] ORGANIZATION NAME: 03 Life Sciences IRS NUMBER: 981480821 STATE OF INCORPORATION: E9 FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 611 GATEWAY BLVD SUITE 223 CITY: SOUTH SAN FRANCISCO STATE: CA ZIP: 94080 BUSINESS PHONE: (628) 229-9277 MAIL ADDRESS: STREET 1: 611 GATEWAY BLVD SUITE 223 CITY: SOUTH SAN FRANCISCO STATE: CA ZIP: 94080 FORMER COMPANY: FORMER CONFORMED NAME: ShouTi Inc. DATE OF NAME CHANGE: 20211019 4 1 doc4.xml FORM 4 SUBMISSION X0508 4 2023-12-22 0 0001888886 Structure Therapeutics Inc. GPCR 0000315066 FMR LLC 245 SUMMER STREET BOSTON MA 02210 0 0 1 1 See Remark 1 0 Ordinary Shares 45120 I F-Prime Capital Partners Life Sciences Advisors Fund VI LP Ordinary Shares 530814 I F-Prime Capital Partners Life Sciences Fund VI LP American Depositary Shares 2023-12-22 4 J 0 25410 0.00 D Ordinary Shares 76230 1564390 I Shares held by persons and entities whose shares are subject to reporting by the undersigned American Depositary Shares Ordinary Shares 123 41 I FIMM, LLC American Depositary Shares Ordinary Shares 8199 2733 I F-Prime Capital Partners Life Sciences Advisors Fund VI LP American Depositary Shares Ordinary Shares 96507 32169 I F-Prime Capital Partners Life Sciences Fund VI LP Reported securities are American Depositary Shares, each of which represents three Ordinary Shares of the Issuer. Any one American Depositary Share may be converted into three Ordinary Shares, and any three Ordinary Shares into one American Depositary Share, at any time at the election of the holder upon notice. These holdings were acquired or disposed of (as applicable) in the form of a distribution without payment of consideration. Remark 1: Abigail P. Johnson is a Director, the Chairman and the Chief Executive Officer of FMR LLC. Members of the Johnson family, including Abigail P. Johnson, are the predominant owners, directly or through trusts, of Series B voting common shares of FMR LLC, representing 49% of the voting power of FMR LLC. The Johnson family group and all other Series B shareholders have entered into a shareholders' voting agreement under which all Series B voting common shares will be voted in accordance with the majority vote of Series B voting common shares. Accordingly, through their ownership of voting common shares and the execution of the shareholders' voting agreement, members of the Johnson family may be deemed, under the Investment Company Act of 1940, to form a controlling group with respect to FMR LLC. The address of Abigail P. Johnson is c/o FMR LLC, 245 Summer Street, Boston, MA 02110. Remark 2: The filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, the undersigned are the beneficial owners of any securities reported herein. Remark 3: F-Prime Capital Partners Life Sciences Advisors Fund VI LP (FPCPLSA) is the general partner of F-Prime Capital Partners Life Sciences Fund VI LP. FPCPLSA is solely managed by Impresa Management LLC, the managing member of its general partner and its investment manager. Impresa Management LLC is owned, directly or indirectly, by various shareholders and employees of FMR LLC, including certain members of the Johnson family. FIMM, LLC is an indirect, wholly-owned subsidiary of FMR LLC. Bryan Comtois, Duly authorized under Powers of Attorney, by and on behalf of FMR LLC and its direct and indirect subsidiaries, and Abigail P. Johnson 2023-12-27 EX-24 2 poa.txt POA DOCUMENT Exhibit 24 POWER OF ATTORNEY WHEREAS, each individual, entity, or group of entities, set forth in Exhibit A hereto (each, a "Grantor") has appointed Stephanie J. Brown with full power of substitution, for the Grantor and in her or its name, to notify companies and to sign such notices, filings or amendments thereto, in respect of interests in shares held, directly or beneficially, by the Grantor, pursuant to the laws and regulations of countries and other jurisdictions within the U.S. and other jurisdictions within North America, Central America, South America, Bermuda, and the Caribbean (collectively, the "Applicable Countries"), as shall from time to time be applicable to the Grantor. NOW, THEREFORE, the undersigned hereby constitutes and appoints Bryan Comtois as her substitute, to have all the powers of the undersigned regarding filings required with respect to each Grantor by the laws and regulations within the Applicable Countries. The Power of Attorney granted herein shall remain in full force and effect only for such time as the undersigned shall continue to be an officer of Fidelity Management & Research Company LLC, provided that, notwithstanding the foregoing, this Power of Attorney may be revoked in whole or in part at any time by the undersigned in writing. By /s/ Stephanie J. Brown Stephanie J. Brown Chief Compliance Officer of Fidelity Management & Research Company LLC Dated: February 3, 2023 Exhibit A 1. Abigail P. Johnson 2. FMR LLC 3. The Fidelity Alternatives Funds for which Fidelity Diversifying Solutions LLC serves as investment adviser 4. The Fidelity Equity and High Income Funds for which Fidelity Management & Research Company LLC serves as investment adviser 5. The Fidelity Fixed Income and Asset Allocation Funds for which Fidelity Management & Research Company LLC serves as investment adviser 6. The Funds for which Strategic Advisers LLC serves as investment adviser 7. FIAM Holdings LLC, FIAM LLC and Fidelity Institutional Asset Management Trust Company 8. Fidelity Advisor Holdings LLC 9. Fidelity Bay Street Holdings LLC 10. Fidelity Canada Investors LLC 11. Fidelity Diversifying Solutions LLC 12. Fidelity Management & Research Company LLC 13. Fidelity Management & Research (Hong Kong) Limited 14. Fidelity Management & Research (Japan) Limited 15. FMR Investment Management (UK) Limited 16. Fidelity Management & Research (Canada) ULC 17. Fidelity Investments Canada ULC 18. Fidelity Management Trust Company 19. Fidelity Personal and Workplace Advisors LLC 20. Strategic Advisers LLC 21. Crosby Advisors LLC 22. Impresa Management LLC and the collective investment vehicles for which Impresa Management LLC acts as manager, general partner or general partner of the general partner 23. Eight Roads Holdings Limited, Eight Roads Investments, and Eight Roads Shareholdings Limited 24. Fidelity Investments Canada ULC 25. FIL Limited and each of its direct and indirect subsidiaries 26. Pandanus Associates, Inc. and Pandanus Partners L.P.