Exhibit (32.1)

Section 1350 Certifications

Pursuant to 18 U.S.C. Section 1350, each of the undersigned officers of Ecolab Inc. does hereby certify that:

(a) the Quarterly Report on Form 10-Q of Ecolab Inc. for the quarter ended March 31, 2022 (the “Report”) fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934; and

(b) information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of Ecolab Inc.

Dated: May 5, 2022	/s/ Christophe Beck
	Christophe Beck
	President and Chief Executive Officer
Dated: May 5, 2022
	/s/ Scott D. Kirkland
	Scott D. Kirkland
	Chief Financial Officer