Pay Versus PerformanceTable. In accordance with Item 402(v), we provide below the tabular disclosure for the Company’s President and Chief Executive Officer (“CEO”) (our Principal Executive Officer) and the average of our NEOs other than the CEO for 2022, 2021 and 2020.

							Value of Initial Fixed $100 Investment Based On:
Fiscal Year⁽¹⁾ (a)	Summary Compensation Table Total for First PEO (b1)	Compensation Actually Paid to First PEO⁽²⁾ (c1)	Summary Compensation Table Total for Second PEO (b2)	Compensation Actually Paid to Second PEO⁽²⁾ (c2)	Average Summary Compensation Table Total for Non-PEO NEOs (d)	Average Compensation Actually Paid to Non-PEO NEOs⁽²⁾ (e)	Total Share- holder Return⁽³⁾ (f)	Peer Group Total Share- holder Return⁽³⁾ (g)	Net Income⁽⁴⁾ (h)	Adjusted EPS⁽⁵⁾ (i)
2022	$20,196,027	$190,304	$0	$0	$6,641,306	$(930,613)	$175	$140	$7,209	$10.97
2021	$17,152,267	$59,455,992	$0	$0	$6,225,036	$26,481,836	$216	$143	$6,433	$10.00
2020	$10,396,761	$32,944,487	$16,763,956	$83,394,550	$6,786,580	$20,676,667	$145	$113	$3,646	$5.11

(1)

For 2020, 2021 and 2022, the First PEO is Rainer Blair. In 2020, the Second PEO is Thomas Joyce. The other NEOs in 2020 were Joakim Weidemanis, Angela Lalor, Matthew McGrew and Brian Ellis; in 2021, the other NEOs were Messrs. Weidemanis and McGrew and Mss. Lalor and Jennifer Honeycutt; and in 2022, the other NEOs were Messrs. Weidemanis and McGrew, Dr. Jose-Carlos Gutierrez-Ramos and Ms. Honeycutt.

(2)

To calculate CAP (columns (c1), (c2), and (e)), the following amounts were deducted from and added to the applicable SCT total compensation:

		*PEO 1*
*Prior FYE* *Current FYE* *Fiscal Year*			*12/31/2019* *12/31/2020* *2020*	*12/31/2020* *12/31/2021* *2021*	*12/31/2021* *12/31/2022* *2022*
SCT Total			$10,396,761	$17,152,267	$20,196,027
—	Grant Date Fair Value of Option Awards and Stock Awards Granted in Fiscal Year		$(6,585,590)	$(11,384,877)	$(14,268,274)
+	Fair Value at Fiscal Year-End of Outstanding and Unvested Option Awards and Stock Awards Granted in Fiscal Year		$12,507,143	$22,940,973	$14,744,612
+	Change in Fair Value of Outstanding and Unvested Option Awards and Stock Awards Granted in Prior Fiscal Year		$15,738,917	$30,678,296	$(14,993,297)
+	Fair Value at Vesting of Option Awards and Stock Awards Granted in Fiscal Year That Vested During Fiscal Year		$0	$0	$0
+	Change in Fair Value as of Vesting Date of Option Awards and Stock Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year		$887,256	$69,332	$(5,488,764)
—	Fair Value as of Prior Fiscal Year-End of Option Awards and Stock Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year		$0	$0	$0
*COMPENSATION ACTUALLY PAID*			*$32,944,487*	*$59,455,992*	*$190,304*

		*PEO 2*
*Prior FYE* *Current FYE* *Fiscal Year*			*12/31/2019* *12/31/2020* *2020*	*12/31/2020* *12/31/2021* *2021*	*12/31/2021* *12/31/2022* *2022*
SCT Total			$16,763,956	$0	$0
—	Grant Date Fair Value of Option Awards and Stock Awards Granted in Fiscal Year		$(11,748,524)	$0	$0
+	Fair Value at Fiscal Year-End of Outstanding and Unvested Option Awards and Stock Awards Granted in Fiscal Year		$24,040,706	$0	$0
+	Change in Fair Value of Outstanding and Unvested Option Awards and Stock Awards Granted in Prior Fiscal Year		$53,508,940	$0	$0
+	Fair Value at Vesting of Option Awards and Stock Awards Granted in Fiscal Year That Vested During Fiscal Year		$0	$0	$0
+	Change in Fair Value as of Vesting Date of Option Awards and Stock Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year		$829,471	$0	$0
—	Fair Value as of Prior Fiscal Year-End of Option Awards and Stock Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year		$0	$0	$0
*COMPENSATION ACTUALLY PAID*			*$83,394,550*	$0	$0

		*Non-PEO NEOs*
*Prior FYE* *Current FYE* *Fiscal Year*			*12/31/2019* *12/31/2020* *2020*	*12/31/2020* *12/31/2021* *2021*	*12/31/2021* *12/31/2022* *2022*
SCT Total			$6,786,580	$6,225,036	$6,641,306
—	Grant Date Fair Value of Option Awards and Stock Awards Granted in Fiscal Year		$(4,178,109)	$(3,370,721)	$(3,945,270)
+	Fair Value at Fiscal Year-End of Outstanding and Unvested Option Awards and Stock Awards Granted in Fiscal Year		$7,853,538	$6,792,180	$4,069,305
+	Change in Fair Value of Outstanding and Unvested Option Awards and Stock Awards Granted in Prior Fiscal Year		$9,403,554	$16,443,088	$(5,970,277)
+	Fair Value at Vesting of Option Awards and Stock Awards Granted in Fiscal Year That Vested During Fiscal Year		$0	$0	$0
+	Change in Fair Value as of Vesting Date of Option Awards and Stock Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year		$811,104	$392,253	$(1,725,677)
—	Fair Value as of Prior Fiscal Year-End of Option Awards and Stock Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year		$0	$0	$0
*COMPENSATION ACTUALLY PAID*			*$20,676,667*	*$26,481,836*	*$(930,613)*

	The fair value of performance stock units (PSUs) used in the calculation of CAP (columns (c1), (c2), and (e)) was determined using a Monte Carlo simulation valuation model, in accordance with ASC 718. The fair value of option awards used in the calculation of CAP was determined using the Black-Scholes option pricing model, in accordance with ASC 718. In both cases, the assumptions used in these calculations are not materially different than those used for purposes of the Summary Compensation Table.
(3)	Reflects TSR indexed to $100 for each of the Company and the S&P 500 Health Care Index, which is an industry line peer group reported in the performance graph included in the Company’s 2022 Annual Report on Form 10-K.
(4)	Values shown are in millions.
(5)	Please see page 43 for a definition of Adjusted EPS. Values shown reflect Adjusted EPS as calculated for purposes of our executive compensation program for the applicable reporting year.

Named Executive Officers, Footnote [Text Block]

For 2020, 2021 and 2022, the First PEO is Rainer Blair. In 2020, the Second PEO is Thomas Joyce. The other NEOs in 2020 were Joakim Weidemanis, Angela Lalor, Matthew McGrew and Brian Ellis; in 2021, the other NEOs were Messrs. Weidemanis and McGrew and Mss. Lalor and Jennifer Honeycutt; and in 2022, the other NEOs were Messrs. Weidemanis and McGrew, Dr. Jose-Carlos Gutierrez-Ramos and Ms. Honeycutt.

Adjustment To PEO Compensation, Footnote [Text Block]

		*PEO 1*
*Prior FYE* *Current FYE* *Fiscal Year*			*12/31/2019* *12/31/2020* *2020*	*12/31/2020* *12/31/2021* *2021*	*12/31/2021* *12/31/2022* *2022*
SCT Total			$10,396,761	$17,152,267	$20,196,027
—	Grant Date Fair Value of Option Awards and Stock Awards Granted in Fiscal Year		$(6,585,590)	$(11,384,877)	$(14,268,274)
+	Fair Value at Fiscal Year-End of Outstanding and Unvested Option Awards and Stock Awards Granted in Fiscal Year		$12,507,143	$22,940,973	$14,744,612
+	Change in Fair Value of Outstanding and Unvested Option Awards and Stock Awards Granted in Prior Fiscal Year		$15,738,917	$30,678,296	$(14,993,297)
+	Fair Value at Vesting of Option Awards and Stock Awards Granted in Fiscal Year That Vested During Fiscal Year		$0	$0	$0
+	Change in Fair Value as of Vesting Date of Option Awards and Stock Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year		$887,256	$69,332	$(5,488,764)
—	Fair Value as of Prior Fiscal Year-End of Option Awards and Stock Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year		$0	$0	$0
*COMPENSATION ACTUALLY PAID*			*$32,944,487*	*$59,455,992*	*$190,304*

		*PEO 2*
*Prior FYE* *Current FYE* *Fiscal Year*			*12/31/2019* *12/31/2020* *2020*	*12/31/2020* *12/31/2021* *2021*	*12/31/2021* *12/31/2022* *2022*
SCT Total			$16,763,956	$0	$0
—	Grant Date Fair Value of Option Awards and Stock Awards Granted in Fiscal Year		$(11,748,524)	$0	$0
+	Fair Value at Fiscal Year-End of Outstanding and Unvested Option Awards and Stock Awards Granted in Fiscal Year		$24,040,706	$0	$0
+	Change in Fair Value of Outstanding and Unvested Option Awards and Stock Awards Granted in Prior Fiscal Year		$53,508,940	$0	$0
+	Fair Value at Vesting of Option Awards and Stock Awards Granted in Fiscal Year That Vested During Fiscal Year		$0	$0	$0
+	Change in Fair Value as of Vesting Date of Option Awards and Stock Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year		$829,471	$0	$0
—	Fair Value as of Prior Fiscal Year-End of Option Awards and Stock Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year		$0	$0	$0
*COMPENSATION ACTUALLY PAID*			*$83,394,550*	$0	$0

Non-PEO NEO Average Compensation Actually Paid Amount

$ (930,613)

26,481,836

20,676,667

Compensation Actually Paid vs. Total Shareholder Return [Text Block]

Relationship between CAP and TSR. The chart below reflects the relationship between the PEO1, PEO2 and Average NEO CAP versus our TSR and the Peer Group TSR. As reflected in the graph below, the Company’s 3-year cumulative TSR exceeds the Peer Group TSR.

Compensation Actually Paid vs. Company Selected Measure [Text Block]

Relationship between CAP and Adjusted EPS (our Company-Selected Measure). The chart below reflects the relationship between the PEO CAP and Average NEO CAP and our Adjusted EPS.