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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001181431-06-024792.txt : 20060421
<SEC-HEADER>0001181431-06-024792.hdr.sgml : 20060421
<ACCEPTANCE-DATETIME>20060421211128
ACCESSION NUMBER:		0001181431-06-024792
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20060421
FILED AS OF DATE:		20060421
DATE AS OF CHANGE:		20060421

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			DANAHER CORP /DE/
		CENTRAL INDEX KEY:			0000313616
		STANDARD INDUSTRIAL CLASSIFICATION:	INDUSTRIAL INSTRUMENTS FOR MEASUREMENT, DISPLAY, AND CONTROL [3823]
		IRS NUMBER:				591995548
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		2099 PENNSYLVANIA AVE N.W., 12TH FLOOR
		CITY:			WASHINGTON
		STATE:			DC
		ZIP:			20006
		BUSINESS PHONE:		2028280850

	MAIL ADDRESS:	
		STREET 1:		2099 PENNSYLVANIA AVE. N.W., 12TH FLOOR
		CITY:			WASHINGTON
		STATE:			DC
		ZIP:			20006

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	DMG INC
		DATE OF NAME CHANGE:	19850221

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RALES MITCHELL P
		CENTRAL INDEX KEY:			0001015014

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-08089
		FILM NUMBER:		06773823

	BUSINESS ADDRESS:	
		STREET 1:		1250 24TH ST NW
		STREET 2:		8TH FL
		CITY:			WASHINGTON
		STATE:			DC
		ZIP:			20037
		BUSINESS PHONE:		2028280850

	MAIL ADDRESS:	
		STREET 1:		1250 24TH ST NW
		STREET 2:		SUITE 800
		CITY:			WASHINGTON
		STATE:			DC
		ZIP:			20037
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd114960.xml
<DESCRIPTION>FORM 4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2006-04-21</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000313616</issuerCik>
        <issuerName>DANAHER CORP /DE/</issuerName>
        <issuerTradingSymbol>DHR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001015014</rptOwnerCik>
            <rptOwnerName>RALES MITCHELL P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>2099 PENNSYLVANIA AVENUE, NW</rptOwnerStreet1>
            <rptOwnerStreet2>12TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>WASHINGTON</rptOwnerCity>
            <rptOwnerState>DC</rptOwnerState>
            <rptOwnerZipCode>20006</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chairman of Exec. Committee</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock, par value $.01 per share</value>
            </securityTitle>
            <transactionDate>
                <value>2006-04-21</value>
            </transactionDate>
            <deemedExecutionDate>
                <value>2006-04-21</value>
            </deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>3000000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>64.95</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>18402971</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $.01 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>23692482</value>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Equity Group Holdings LLC and Equity Group Holdings II LLC</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock, par value $.01 per share</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>41294</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By 401(k) Plan</value>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">This amount represents the average price from the sale of (i) 2,664,100 shares of Danaher Corporation Common Stock, par value $.01 per share (&quot;the Shares&quot;), at a price of $64.86 per share and (ii) 335,900 Shares in numerous transactions at prices ranging from $65.25 to $66.40 per share.</footnote>
        <footnote id="F2">On April 21, 2006, the reporting person received a distribution of 4,314,888 Shares from Equity Group Holdings LLC and 1,846,241 Shares from Equity Group Holdings II LLC for no consideration in transactions exempt from reporting under Rule 16a-13.</footnote>
        <footnote id="F3">The reported Shares include 20,000,000 Shares beneficially owned by Equity Group Holdings LLC and 3,692,482 Shares beneficially owned by Equity Group Holdings II LLC. Mitchell P. Rales and his brother, Steven M. Rales, are the sole members of Equity Group Holdings LLC and Equity Group Holdings II LLC.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Mitchell P. Rales</signatureName>
        <signatureDate>2006-04-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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