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Income Taxes Effective rate reconcilation (Tables)
 12 Months Ended
Dec. 31, 2014
Effective Rate Reconciliation [Abstract]  
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
The provision for income taxes differs from the amount estimated by applying the statutory Federal income tax rate to loss before taxes as follows (in thousands):
 
Year ended December 31,
 
2014
 
2013
 
2012
Federal tax at statutory rate of 35%
$
(5,390
)
 
$
(5,050
)
 
$
(4,537
)
State taxes, net of federal benefit
(577
)
 
17

 
5

U.S.-Foreign rate differential
100

 
342

 
87

Change in Valuation Allowance
4,115

 
5,862

 
4,530

Research and Development credits
357

 
(1,241
)
 
—

Permanent items
1,560

 
406

 
—

Others
46

 
(25
)
 
134

Total income tax expense
$
211

 
$
311

 
$
219