Goodwill and Other Intangible Assets, Net - Intangible Assets (Details) - USD ($) $ in Thousands	3 Months Ended			12 Months Ended
	Mar. 31, 2019	Dec. 31, 2018	Mar. 31, 2018	Dec. 31, 2018
Indefinite-lived Intangible Assets
Impairment	$ (10,354)		$ (18,815)
Finite-Lived Intangible Assets
Accumulated Amortization	(224,022)	$ (217,603)	(232,200)	$ (217,603)
Reclassifications	0	0
Gross Amount	502,666	778,581		778,581
Impairment	(15,000)	(276,002)
Net Balance	263,644	284,976		284,976
IPR&D
Indefinite-lived Intangible Assets
Gross Amount	4,400	149,161		149,161
Reclassifications	0	(5,300)
Impairment	0	(139,461)	$ (17,900)
Net Balance	4,400	4,400		4,400
Product licensing rights
Finite-Lived Intangible Assets
Gross Amount	472,041	597,960		597,960
Accumulated Amortization	(209,135)	(203,323)		(203,323)
Reclassifications	0	5,300
Impairment	(15,000)	(131,306)
Net Balance	$ 247,906	268,631		$ 268,631
Wtd Avg Remaining Amortization Period (years)	8 years 10 months 25 days			9 years 2 months 12 days
Trademarks
Finite-Lived Intangible Assets
Gross Amount	$ 16,000	16,000		$ 16,000
Accumulated Amortization	(6,535)	(6,304)		(6,304)
Reclassifications	0	0
Impairment	0	0
Net Balance	$ 9,465	9,696		$ 9,696
Wtd Avg Remaining Amortization Period (years)	17 years 4 months 24 days			17 years 6 months
Customer relationships
Finite-Lived Intangible Assets
Gross Amount	$ 4,225	4,225		$ 4,225
Accumulated Amortization	(2,383)	(2,318)		(2,318)
Reclassifications	0	0
Impairment	0	0
Net Balance	$ 1,842	1,907		$ 1,907
Wtd Avg Remaining Amortization Period (years)	7 years 1 month 6 days			7 years 3 months 19 days
Other intangibles
Finite-Lived Intangible Assets
Gross Amount	$ 6,000	11,235		$ 11,235
Accumulated Amortization	(5,969)	(5,658)		(5,658)
Reclassifications	0	0
Impairment	0	(5,235)
Net Balance	$ 31	$ 342		$ 342
Wtd Avg Remaining Amortization Period (years)	0 years			3 months 19 days