Goodwill and Other Intangible Assets, Net - Additional Information (Details)	3 Months Ended			12 Months Ended
	Mar. 31, 2019 USD ($) product	Dec. 31, 2018 USD ($)	Mar. 31, 2018 USD ($) product	Dec. 31, 2018 USD ($)
Finite-Lived Intangible Assets
Accumulated Amortization	$ 224,022,000	$ 217,603,000	$ 232,200,000	$ 217,603,000
Amortization of intangibles	11,065,000		13,190,000
Impairment of intangible assets, indefinite-lived	10,354,000		18,815,000
Impairment of goodwill	$ 15,955,000		$ 0	0
IPR&D
Finite-Lived Intangible Assets
Number of products impaired | product	0		3
Impairment of intangible assets, indefinite-lived	$ 0	139,461,000	$ 17,900,000
Product licensing rights
Finite-Lived Intangible Assets
Accumulated Amortization	$ 209,135,000	203,323,000		203,323,000
Number of products impaired | product	1		1
Impairment of intangible assets, finite-lived	$ 10,400,000		$ 900,000
Impairment of intangible assets	15,000,000.0	131,306,000
Impairment of intangible assets, accumulated amortization	4,600,000
Other Intangibles
Finite-Lived Intangible Assets
Accumulated Amortization	5,969,000	5,658,000		$ 5,658,000
Impairment of intangible assets	$ 0	$ 5,235,000
Minimum
Finite-Lived Intangible Assets
Intangible asset useful life	1 year
Maximum
Finite-Lived Intangible Assets
Intangible asset useful life	30 years
Other Operating Income (Expense) | Product licensing rights
Finite-Lived Intangible Assets
Impairment of intangible assets, finite-lived	$ 10,400,000