Goodwill and Other Intangible Assets, Net - Intangible Assets (Details) - USD ($)	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2018	Sep. 30, 2017	Sep. 30, 2018	Sep. 30, 2017	Dec. 31, 2017
Finite-Lived Intangible Assets
Accumulated Amortization	$ (257,210,000)	$ (235,000,000)	$ (257,210,000)	$ (235,000,000)	$ (219,026,000)
Gross Amount	788,560,000		788,560,000		952,323,000
Gross Impairment			(114,798,000)		(163,813,000)
Net Balance	416,552,000		416,552,000		569,484,000
IPR&D
Indefinite-lived Intangible Assets
Gross Amount	149,161,000		149,161,000		173,757,000
Reclassifications			(5,300,000)		0
Gross Impairment	(20,600,000)	$ 0	(100,073,000)	$ (3,400,000)	(24,596,000)
Net Balance	43,788,000		43,788,000		149,161,000
Product licensing rights
Finite-Lived Intangible Assets
Gross Amount	607,939,000		607,939,000		747,106,000
Accumulated Amortization	(241,555,000)		(241,555,000)		(205,549,000)
Reclassifications			5,300,000		0
Gross Impairment			(14,725,000)		(139,217,000)
Net Balance	356,959,000		$ 356,959,000		$ 402,340,000
Wtd Avg Remaining Amortization Period (years)			8 years 9 months 18 days		9 years 9 months 18 days
Trademarks
Finite-Lived Intangible Assets
Gross Amount	16,000,000		$ 16,000,000		$ 16,000,000
Accumulated Amortization	(6,071,000)		(6,071,000)		(5,376,000)
Reclassifications			0		0
Gross Impairment			0		0
Net Balance	9,929,000		$ 9,929,000		$ 10,624,000
Wtd Avg Remaining Amortization Period (years)			17 years 6 months		17 years 9 months 18 days
Customer relationships
Finite-Lived Intangible Assets
Gross Amount	4,225,000		$ 4,225,000		$ 4,225,000
Accumulated Amortization	(2,253,000)		(2,253,000)		(2,058,000)
Reclassifications			0		0
Gross Impairment			0		0
Net Balance	1,972,000		$ 1,972,000		$ 2,167,000
Wtd Avg Remaining Amortization Period (years)			7 years 7 months 6 days		8 years 3 months 19 days
Other intangibles
Finite-Lived Intangible Assets
Gross Amount	11,235,000		$ 11,235,000		$ 11,235,000
Accumulated Amortization	(7,331,000)		(7,331,000)		(6,043,000)
Reclassifications			0		0
Gross Impairment			0		0
Net Balance	$ 3,904,000		$ 3,904,000		$ 5,192,000
Wtd Avg Remaining Amortization Period (years)			5 years 9 months 18 days		5 years 8 months 12 days