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Goodwill and Other Intangible Assets, Net - Additional Information (Details)
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2018
USD ($)
product
$ / shares
Sep. 30, 2017
USD ($)
product
Sep. 30, 2018
USD ($)
product
$ / shares
Sep. 30, 2017
USD ($)
product
Dec. 31, 2017
USD ($)
Oct. 01, 2018
$ / shares
Finite-Lived Intangible Assets            
Accumulated amortization $ 257,210,000 $ 235,000,000 $ 257,210,000 $ 235,000,000 $ 219,026,000  
Amortization of intangibles $ 13,613,000 15,316,000 $ 39,985,000 $ 46,291,000    
IPR&D            
Finite-Lived Intangible Assets            
Number of products impaired | product 8   16 1    
Impairment of intangible assets, indefinite-lived $ 20,600,000 $ 0 $ 100,073,000 $ 3,400,000 $ 24,596,000  
Product licensing rights            
Finite-Lived Intangible Assets            
Intangible asset useful life     8 years 9 months 18 days   9 years 9 months 18 days  
Accumulated amortization $ 241,555,000   $ 241,555,000   $ 205,549,000  
Number of products impaired | product 6 1 10 3    
Impairment of intangible assets, finite-lived $ 9,000,000 $ 7,600,000 $ 12,900,000 $ 12,300,000    
Product licensing rights | Research and Development Expense            
Finite-Lived Intangible Assets            
Impairment of intangible assets, finite-lived $ 2,300,000   $ 4,100,000 $ 1,600,000    
Minimum            
Finite-Lived Intangible Assets            
Intangible asset useful life     1 year      
Maximum            
Finite-Lived Intangible Assets            
Intangible asset useful life     30 years      
Common Stock            
Finite-Lived Intangible Assets            
Share price (in dollars per share) | $ / shares $ 12.98   $ 12.98      
Subsequent Event | Common Stock            
Finite-Lived Intangible Assets            
Share price (in dollars per share) | $ / shares           $ 5.36