Goodwill and Other Intangible Assets, Net - Intangible Assets (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017	Dec. 31, 2017
Finite-Lived Intangible Assets
Accumulated Amortization	$ (244,900)	$ (220,600)	$ (244,900)	$ (220,600)	$ (219,026)
Gross Amount	788,560		788,560		952,323
Gross Impairment			(83,848)		(163,813)
Net Balance	459,812		459,812		569,484
IPR&D
Indefinite-lived Intangible Assets
Gross Amount	149,161		149,161		173,757
Reclassifications			(5,300)		0
Gross Impairment	(61,600)	$ (3,200)	(79,473)	$ (3,400)	(24,596)
Net Balance	64,388		64,388		149,161
Product licensing rights
Finite-Lived Intangible Assets
Gross Amount	607,939		607,939		747,106
Accumulated Amortization	(229,970)		(229,970)		(205,549)
Reclassifications			5,300		0
Gross Impairment			(4,375)		(139,217)
Net Balance	378,894		$ 378,894		$ 402,340
Wtd Avg Remaining Amortization Period (years)			9 years		9 years 9 months 18 days
Trademarks
Finite-Lived Intangible Assets
Gross Amount	16,000		$ 16,000		$ 16,000
Accumulated Amortization	(5,840)		(5,840)		(5,376)
Reclassifications			0		0
Gross Impairment			0		0
Net Balance	10,160		$ 10,160		$ 10,624
Wtd Avg Remaining Amortization Period (years)			17 years 7 months 6 days		17 years 9 months 18 days
Customer relationships
Finite-Lived Intangible Assets
Gross Amount	4,225		$ 4,225		$ 4,225
Accumulated Amortization	(2,188)		(2,188)		(2,058)
Reclassifications			0		0
Gross Impairment			0		0
Net Balance	2,037		$ 2,037		$ 2,167
Wtd Avg Remaining Amortization Period (years)			7 years 9 months 18 days		8 years 3 months 19 days
Other intangibles
Finite-Lived Intangible Assets
Gross Amount	11,235		$ 11,235		$ 11,235
Accumulated Amortization	(6,902)		(6,902)		(6,043)
Reclassifications			0		0
Gross Impairment			0		0
Net Balance	$ 4,333		$ 4,333		$ 5,192
Wtd Avg Remaining Amortization Period (years)			5 years 8 months 12 days		5 years 8 months 12 days