Goodwill and Other Intangible Assets - Changes In Intangible Assets (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Finite-lived Intangible Assets [Roll Forward]
Amortization	$ (61,443)	$ (65,713)	$ (66,272)
Impairment - finite lived intangible assets	(92,613)	(40,519)	(30,376)
Balance at end of period	420,323
IPR&D
Indefinite-lived Intangible Assets [Roll Forward]
Balance at beginning of period	173,757	186,932
Indefinite lived acquisitions	0	75
Impairment - indefinite lived intangible assets	(24,596)	(3,850)
Reclassifications		(9,400)
Balance at end of period	149,161	173,757	186,932
Product licensing rights
Finite-lived Intangible Assets [Roll Forward]
Balance at beginning of period	564,005	653,627
Finite lived acquisitions	200	3,872
Amortization	(58,335)	(62,375)
Impairment - finite lived intangible assets	(103,530)	(40,519)
Reclassifications		9,400
Balance at end of period	402,340	564,005	653,627
Trademarks
Finite-lived Intangible Assets [Roll Forward]
Balance at beginning of period	11,756	13,018
Finite lived acquisitions	0	0
Amortization	(1,132)	(1,262)
Impairment - finite lived intangible assets	0	0
Reclassifications		0
Balance at end of period	10,624	11,756	13,018
Customer relationships
Finite-lived Intangible Assets [Roll Forward]
Balance at beginning of period	2,427	2,777
Finite lived acquisitions	0	0
Amortization	(260)	(350)
Impairment - finite lived intangible assets	0	0
Reclassifications		0
Balance at end of period	2,167	2,427	2,777
Other intangibles
Finite-lived Intangible Assets [Roll Forward]
Balance at beginning of period	6,909	8,635
Finite lived acquisitions	0	0
Amortization	(1,717)	(1,726)
Impairment - finite lived intangible assets	0	0
Reclassifications		0
Balance at end of period	5,192	6,909	8,635
Non-compete agreements
Finite-lived Intangible Assets [Roll Forward]
Balance at beginning of period	0	0
Finite lived acquisitions	0	0
Amortization	0	0
Impairment - finite lived intangible assets	0	0
Reclassifications		0
Balance at end of period	$ 0	$ 0	$ 0