Goodwill and Other Intangible Assets (Details) - Changes in intangible assets - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Balance at beginning of period	$ 864,989
Amortization	(65,713)	$ (66,272)	$ (43,493)
Impairment - finite lived intangible assets	(40,519)	(30,376)	0
Balance at end of period	758,854	864,989
IPR&D
Balance at beginning of period	186,932	227,259
Indefinite lived acquisitions	75	300
Impairment - indefinite lived intangible assets	(3,850)	(2,627)
Dispositions	0
Foreign currency translation	0	0
Reclassifications	(9,400)	(38,000)
Balance at end of period	173,757	186,932	227,259
Product licensing rights
Balance at beginning of period	653,627	704,791
Finite lived acquisitions	3,872	3,535
Amortization	(62,375)	(62,323)
Impairment - finite lived intangible assets	(40,519)	(30,376)
Dispositions	0
Foreign currency translation	0	0
Reclassifications	9,400	38,000
Balance at end of period	564,005	653,627	704,791
Trademarks
Balance at beginning of period	13,018	14,279
Finite lived acquisitions	0	0
Amortization	(1,262)	(1,261)
Impairment - finite lived intangible assets	0	0
Dispositions	0
Foreign currency translation	0	0
Reclassifications	0	0
Balance at end of period	11,756	13,018	14,279
Customer relationships
Balance at beginning of period	2,777	3,035
Finite lived acquisitions	0	0
Amortization	(350)	(381)
Impairment - finite lived intangible assets	0	0
Dispositions	0
Foreign currency translation	0	123
Reclassifications	0	0
Balance at end of period	2,427	2,777	3,035
Other intangibles
Balance at beginning of period	8,635	10,356
Finite lived acquisitions	0	0
Amortization	(1,726)	(1,721)
Impairment - finite lived intangible assets	0	0
Dispositions	0
Foreign currency translation	0	0
Reclassifications	0	0
Balance at end of period	6,909	8,635	10,356
Non-compete agreements
Balance at beginning of period	0	683
Finite lived acquisitions	0	0
Amortization	0	(586)
Impairment - finite lived intangible assets	0	0
Dispositions	0
Foreign currency translation	0	(97)
Reclassifications	0	0
Balance at end of period	$ 0	$ 0	$ 683