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Financial Instruments - Narrative (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Jan. 31, 2025
Derivative [Line Items]        
Total Swap Notional Amount $ 38,560 $ 30,551    
Pretax net unrealized losses on derivatives maturing within the next 12 months estimated to be reclassified from AOCI to sales (262)      
Equity investments without readily determinable fair values 863 832    
Unrealized gains recognized on investments in equity securities without readily determinable fair value 19 10    
Unrealized losses recognized on investments in equity securities without readily determinable fair values 51 61    
Cumulative upward price adjustment 309      
Cumulative downward price adjustment 107      
(Income) loss from investments in equity securities, net (14) (340) $ 1,419  
Payments of contingent consideration 151 117    
Fair value of loans payable and long-term debt, including current portion 32,600 32,000    
Debt, carrying amount 37,100 35,100    
Factored accounts receivable 2,100 3,000    
Cash collateral received from counterparties $ 165 3    
5.00% notes due 2053        
Derivative [Line Items]        
Stated interest rate 5.00%      
Senior Notes | Subsequent Event | 5.00% notes due 2053        
Derivative [Line Items]        
Stated interest rate       5.00%
Interest rate swap contracts | 5.00% notes due 2053 | Subsequent Event        
Derivative [Line Items]        
Total Swap Notional Amount       $ 250
Lyfnua        
Derivative [Line Items]        
Payments of contingent consideration $ 25      
Sanofi Pasteur        
Derivative [Line Items]        
Payments of contingent consideration 126      
Equity Funds        
Derivative [Line Items]        
Equity securities held through ownership interests in investment funds 267 417 598  
(Income) loss from investments in equity securities, net 29 106 $ 1,000  
Accounts Receivable Factoring Collections        
Derivative [Line Items]        
Funds collected from factoring of receivable, held in restricted cash $ 55 44    
Customer Concentration Risk | Accounts Receivable | McKesson Corporation        
Derivative [Line Items]        
Percentage of accounts receivable represented by customers with largest balances 21.00%      
Customer Concentration Risk | Accounts Receivable | Cencora, Inc.        
Derivative [Line Items]        
Percentage of accounts receivable represented by customers with largest balances 21.00%      
Customer Concentration Risk | Accounts Receivable | Cardinal Health, Inc.        
Derivative [Line Items]        
Percentage of accounts receivable represented by customers with largest balances 13.00%      
Level 2        
Derivative [Line Items]        
Cash equivalents $ 12,300 6,000    
Derivatives Designated as Hedging Instruments        
Derivative [Line Items]        
Total Swap Notional Amount 12,465 12,754    
Derivatives Not Designated as Hedging Instruments        
Derivative [Line Items]        
Total Swap Notional Amount $ 26,095 $ 17,797    
Maximum | Derivatives Designated as Hedging Instruments        
Derivative [Line Items]        
Term of derivative contract 2 years      
Maximum | Derivatives Not Designated as Hedging Instruments        
Derivative [Line Items]        
Maximum planning cycle of hedges (less than) 6 months