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Taxes on Income - Reconciliation Between Effective Tax Rate and US Statutory Rate (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Amount      
U.S. statutory rate applied to income before taxes $ 4,186 $ 397 $ 3,453
Differential arising from:      
Foreign earnings (1,301) (941) (1,821)
Tax settlements and statute lapses (557) 0 (10)
R&D tax credit (202) (214) (117)
Inventory donations (71) (65) (52)
State taxes (39) (117) (110)
Charges for certain research and development asset acquisitions 554 253 0
Valuation allowances 54 70 108
Restructuring 52 41 11
GILTI and the foreign-derived intangible income deduction 29 (80) 462
Acquisition-related costs, including amortization 18 42 (3)
Acquisition of Prometheus 0 2,139 0
Other 80 (13) (3)
Taxes on income $ 2,803 $ 1,512 $ 1,918
Tax Rate      
U.S. statutory rate applied to income before taxes 21.00% 21.00% 21.00%
Differential arising from:      
Foreign earnings (6.50%) (49.80%) (11.10%)
Tax settlements and statute lapses (2.80%) 0.00% (0.10%)
R&D tax credit (1.00%) (11.30%) (0.70%)
Inventory donations (0.40%) (3.50%) (0.30%)
State taxes (0.20%) (6.20%) (0.70%)
Charges for certain research and development asset acquisitions 2.80% 13.40% 0.00%
Valuation allowances 0.30% 3.70% 0.70%
Restructuring 0.30% 2.20% 0.10%
GILTI and the foreign-derived intangible income deduction 0.10% (4.30%) 2.80%
Acquisition-related costs, including amortization 0.10% 2.20% 0.00%
Acquisition of Prometheus 0.00% 113.30% 0.00%
Other 0.40% (0.70%) 0.00%
Total, Tax Rate 14.10% 80.00% 11.70%