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Equity (Details) - USD ($)
$ / shares in Units, $ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Common stock, beginning balance (in shares)     3,577,103,522  
Treasury stock, beginning balance (in shares)     1,039,269,638  
Equity, beginning balance $ 46,905 $ 40,953 $ 46,058 $ 38,257
Net (loss) income attributable to Merck & Co., Inc. (5,975) 3,944 (3,154) 8,254
Other comprehensive income (loss), net of taxes (17) 42 (132) 102
Cash dividends declared on common stock (1,866) (1,759) (3,729) (3,513)
Treasury stock shares purchased (338)   (487)  
Share-based compensation plans and other 55 133 204 216
Net income attributable to noncontrolling interests 3 5 7 2
Distributions attributable to noncontrolling interests $ (25)   $ (25)  
Common stock, ending balance (in shares) 3,577,103,522   3,577,103,522  
Treasury stock, ending balance (in shares) 1,037,678,033   1,037,678,033  
Equity, ending balance $ 38,742 $ 43,318 $ 38,742 $ 43,318
Cash dividends declared on common stock (in dollars per share) $ 0.73 $ 0.69 $ 1.46 $ 1.38
  Common Stock        
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Common stock, beginning balance (in shares) 3,577,000,000 3,577,000,000 3,577,000,000 3,577,000,000
Equity, beginning balance $ 1,788 $ 1,788 $ 1,788 $ 1,788
Common stock, ending balance (in shares) 3,577,000,000 3,577,000,000 3,577,000,000 3,577,000,000
Equity, ending balance $ 1,788 $ 1,788 $ 1,788 $ 1,788
Other Paid-In Capital        
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Equity, beginning balance 44,467 44,275 44,379 44,238
Share-based compensation plans and other (248) (160) (160) (123)
Equity, ending balance 44,219 44,115 44,219 44,115
Retained Earnings        
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Equity, beginning balance 62,039 56,252 61,081 53,696
Net (loss) income attributable to Merck & Co., Inc. (5,975) 3,944 (3,154) 8,254
Cash dividends declared on common stock (1,866) (1,759) (3,729) (3,513)
Equity, ending balance 54,198 58,437 54,198 58,437
Accumulated Other Comprehensive Loss        
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Equity, beginning balance (4,883) (4,369) (4,768) (4,429)
Other comprehensive income (loss), net of taxes (17) 42 (132) 102
Equity, ending balance $ (4,900) $ (4,327) $ (4,900) $ (4,327)
 Treasury Stock        
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Treasury stock, beginning balance (in shares) 1,040,000,000 1,049,000,000 1,039,000,000 1,049,000,000
Equity, beginning balance $ (56,577) $ (57,063) $ (56,489) $ (57,109)
Treasury stock shares purchased (in shares) 3,000,000   4,000,000  
Treasury stock shares purchased $ (338)   $ (487)  
Share-based compensation plans and other (in shares) (5,000,000) (5,000,000) (5,000,000) (5,000,000)
Share-based compensation plans and other $ 303 $ 293 $ 364 $ 339
Treasury stock, ending balance (in shares) 1,038,000,000 1,044,000,000 1,038,000,000 1,044,000,000
Equity, ending balance $ (56,612) $ (56,770) $ (56,612) $ (56,770)
Non- controlling Interests        
Increase (Decrease) in Stockholders' Equity [Roll Forward]        
Equity, beginning balance 71 70 67 73
Net income attributable to noncontrolling interests 3 5 7 2
Distributions attributable to noncontrolling interests (25)   (25)  
Equity, ending balance $ 49 $ 75 $ 49 $ 75