Goodwill and Other Intangibles - Goodwill Activity by Segment (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Goodwill [Roll Forward]
Goodwill, beginning balance	$ 21,264	$ 18,882
Acquisitions		2,436
Other	(60)	(54)
Goodwill, ending balance	21,204	21,264
Accumulated goodwill impairment losses	531	531
Pharmaceutical
Goodwill [Roll Forward]
Goodwill, beginning balance	17,997	15,614
Acquisitions		2,431
Other	(61)	(48)
Goodwill, ending balance	17,936	17,997
Animal Health
Goodwill [Roll Forward]
Goodwill, beginning balance	3,267	3,268
Acquisitions		5
Other	1	(6)
Goodwill, ending balance	$ 3,268	$ 3,267