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Segment Reporting - Profits to Income Before Taxes (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Segment Reporting Information [Line Items]        
Profits $ 3,519 $ 3,259 $ 7,357 $ 6,326
Interest income 14 75 39 164
Interest expense (209) (233) (421) (442)
Depreciation and amortization     (1,869) (1,871)
Research and development (2,123) (2,189) (4,331) (4,119)
Restructuring costs (83) (59) (155) (212)
Total segment profits        
Segment Reporting Information [Line Items]        
Profits 6,967 7,518 14,923 14,510
Total segment profits | Pharmaceutical segment        
Segment Reporting Information [Line Items]        
Profits 6,560 7,115 14,036 13,690
Total segment profits | Animal Health segment        
Segment Reporting Information [Line Items]        
Profits 407 405 885 820
Total segment profits | Other segment        
Segment Reporting Information [Line Items]        
Profits 0 (2) 2 0
Other profits        
Segment Reporting Information [Line Items]        
Profits 61 94 200 124
Unallocated        
Segment Reporting Information [Line Items]        
Interest income 14 75 39 164
Interest expense (209) (233) (421) (442)
Depreciation and amortization (390) (427) (772) (786)
Research and development (1,994) (2,093) (4,092) (3,935)
Amortization of purchase accounting adjustments (299) (378) (594) (775)
Restructuring costs (83) (59) (155) (212)
Other unallocated, net $ (548) $ (1,238) $ (1,771) $ (2,322)