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Segment Reporting - Sales of Company's Products (Details) - USD ($)
$ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2020
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Segment Reporting Information [Line Items]        
Sales $ 10,872 $ 11,760 $ 22,929 $ 22,575
Proceeds from Sale of Intangible Assets     85 15
Operating Segments        
Segment Reporting Information [Line Items]        
Sales 10,780 11,632 22,671 22,359
Other        
Segment Reporting Information [Line Items]        
Sales 92 128 258 216
United States        
Segment Reporting Information [Line Items]        
Sales 4,634 5,193 9,771 9,748
United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 4,612 5,189 9,733 9,736
United States | Other        
Segment Reporting Information [Line Items]        
Sales 22 4 38 12
International        
Segment Reporting Information [Line Items]        
Sales 6,238 6,567 13,158 12,828
International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 6,168 6,442 12,938 12,622
International | Other        
Segment Reporting Information [Line Items]        
Sales 70 125 220 206
Total Pharmaceutical segment sales | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 9,679 10,460 20,334 20,123
Total Pharmaceutical segment sales | Operating Segments | Keytruda        
Segment Reporting Information [Line Items]        
Sales 3,388 2,634 6,672 4,903
Total Pharmaceutical segment sales | Operating Segments | Alliance revenue - Lynparza (1)        
Segment Reporting Information [Line Items]        
Sales 178 111 323 190
Total Pharmaceutical segment sales | Operating Segments | Alliance revenue - Lenvima (1)        
Segment Reporting Information [Line Items]        
Sales 151 97 279 171
Total Pharmaceutical segment sales | Operating Segments | Emend        
Segment Reporting Information [Line Items]        
Sales 33 121 76 237
Total Pharmaceutical segment sales | Operating Segments | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 656 886 1,753 1,724
Total Pharmaceutical segment sales | Operating Segments | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 378 675 813 1,171
Total Pharmaceutical segment sales | Operating Segments | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 168 172 391 383
Total Pharmaceutical segment sales | Operating Segments | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 117 170 373 355
Total Pharmaceutical segment sales | Operating Segments | Vaqta        
Segment Reporting Information [Line Items]        
Sales 28 58 88 105
Total Pharmaceutical segment sales | Operating Segments | Bridion        
Segment Reporting Information [Line Items]        
Sales 224 278 524 533
Total Pharmaceutical segment sales | Operating Segments | Noxafil        
Segment Reporting Information [Line Items]        
Sales 73 193 168 383
Total Pharmaceutical segment sales | Operating Segments | Prevymis        
Segment Reporting Information [Line Items]        
Sales 63 38 123 70
Total Pharmaceutical segment sales | Operating Segments | Primaxin        
Segment Reporting Information [Line Items]        
Sales 64 71 115 130
Total Pharmaceutical segment sales | Operating Segments | Invanz        
Segment Reporting Information [Line Items]        
Sales 43 78 108 150
Total Pharmaceutical segment sales | Operating Segments | Cancidas        
Segment Reporting Information [Line Items]        
Sales 43 67 98 129
Total Pharmaceutical segment sales | Operating Segments | Cubicin        
Segment Reporting Information [Line Items]        
Sales 32 67 78 155
Total Pharmaceutical segment sales | Operating Segments | Zerbaxa        
Segment Reporting Information [Line Items]        
Sales 32 27 69 53
Total Pharmaceutical segment sales | Operating Segments | Simponi        
Segment Reporting Information [Line Items]        
Sales 191 214 406 422
Total Pharmaceutical segment sales | Operating Segments | Remicade        
Segment Reporting Information [Line Items]        
Sales 73 98 160 221
Total Pharmaceutical segment sales | Operating Segments | Belsomra        
Segment Reporting Information [Line Items]        
Sales 84 76 163 143
Total Pharmaceutical segment sales | Operating Segments | Isentress/Isentress HD        
Segment Reporting Information [Line Items]        
Sales 196 247 441 502
Total Pharmaceutical segment sales | Operating Segments | Zepatier        
Segment Reporting Information [Line Items]        
Sales 39 108 94 221
Total Pharmaceutical segment sales | Operating Segments | Zetia        
Segment Reporting Information [Line Items]        
Sales 137 156 282 296
Total Pharmaceutical segment sales | Operating Segments | Vytorin        
Segment Reporting Information [Line Items]        
Sales 39 76 92 174
Total Pharmaceutical segment sales | Operating Segments | Atozet        
Segment Reporting Information [Line Items]        
Sales 115 92 238 186
Total Pharmaceutical segment sales | Operating Segments | Alliance revenue - Adempas (2)        
Segment Reporting Information [Line Items]        
Sales 79 51 133 94
Total Pharmaceutical segment sales | Operating Segments | Adempas        
Segment Reporting Information [Line Items]        
Sales 57 53 113 100
Total Pharmaceutical segment sales | Operating Segments | Januvia        
Segment Reporting Information [Line Items]        
Sales 854 908 1,628 1,732
Total Pharmaceutical segment sales | Operating Segments | Janumet        
Segment Reporting Information [Line Items]        
Sales 490 533 993 1,063
Total Pharmaceutical segment sales | Operating Segments | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 132 183 326 382
Total Pharmaceutical segment sales | Operating Segments | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 63 240 126 459
Total Pharmaceutical segment sales | Operating Segments | Singulair        
Segment Reporting Information [Line Items]        
Sales 100 160 255 352
Total Pharmaceutical segment sales | Operating Segments | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 98 109 200 213
Total Pharmaceutical segment sales | Operating Segments | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 65 75 135 149
Total Pharmaceutical segment sales | Operating Segments | Nasonex        
Segment Reporting Information [Line Items]        
Sales 49 72 120 168
Total Pharmaceutical segment sales | Operating Segments | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 44 63 85 121
Total Pharmaceutical segment sales | Operating Segments | Other pharmaceutical (3)        
Segment Reporting Information [Line Items]        
Sales 1,103 1,203 2,293 2,283
Total Pharmaceutical segment sales | United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 4,270 4,807 8,984 9,022
Total Pharmaceutical segment sales | United States | Operating Segments | Keytruda        
Segment Reporting Information [Line Items]        
Sales 2,043 1,498 3,949 2,782
Total Pharmaceutical segment sales | United States | Operating Segments | Alliance revenue - Lynparza (1)        
Segment Reporting Information [Line Items]        
Sales 105 66 190 116
Total Pharmaceutical segment sales | United States | Operating Segments | Alliance revenue - Lenvima (1)        
Segment Reporting Information [Line Items]        
Sales 98 54 188 104
Total Pharmaceutical segment sales | United States | Operating Segments | Emend        
Segment Reporting Information [Line Items]        
Sales 6 67 11 130
Total Pharmaceutical segment sales | United States | Operating Segments | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 168 456 629 818
Total Pharmaceutical segment sales | United States | Operating Segments | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 263 500 596 843
Total Pharmaceutical segment sales | United States | Operating Segments | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 100 104 241 258
Total Pharmaceutical segment sales | United States | Operating Segments | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 21 123 203 248
Total Pharmaceutical segment sales | United States | Operating Segments | Vaqta        
Segment Reporting Information [Line Items]        
Sales 17 38 47 67
Total Pharmaceutical segment sales | United States | Operating Segments | Bridion        
Segment Reporting Information [Line Items]        
Sales 107 129 250 248
Total Pharmaceutical segment sales | United States | Operating Segments | Noxafil        
Segment Reporting Information [Line Items]        
Sales 6 100 14 191
Total Pharmaceutical segment sales | United States | Operating Segments | Prevymis        
Segment Reporting Information [Line Items]        
Sales 28 19 55 37
Total Pharmaceutical segment sales | United States | Operating Segments | Primaxin        
Segment Reporting Information [Line Items]        
Sales 1 0 1 1
Total Pharmaceutical segment sales | United States | Operating Segments | Invanz        
Segment Reporting Information [Line Items]        
Sales 0 18 6 31
Total Pharmaceutical segment sales | United States | Operating Segments | Cancidas        
Segment Reporting Information [Line Items]        
Sales (2) 3 1 4
Total Pharmaceutical segment sales | United States | Operating Segments | Cubicin        
Segment Reporting Information [Line Items]        
Sales 10 22 25 64
Total Pharmaceutical segment sales | United States | Operating Segments | Zerbaxa        
Segment Reporting Information [Line Items]        
Sales 17 13 37 25
Total Pharmaceutical segment sales | United States | Operating Segments | Simponi        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Remicade        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Belsomra        
Segment Reporting Information [Line Items]        
Sales 22 21 49 45
Total Pharmaceutical segment sales | United States | Operating Segments | Isentress/Isentress HD        
Segment Reporting Information [Line Items]        
Sales 76 94 151 202
Total Pharmaceutical segment sales | United States | Operating Segments | Zepatier        
Segment Reporting Information [Line Items]        
Sales 15 39 33 72
Total Pharmaceutical segment sales | United States | Operating Segments | Zetia        
Segment Reporting Information [Line Items]        
Sales (1) 6 (4) 6
Total Pharmaceutical segment sales | United States | Operating Segments | Vytorin        
Segment Reporting Information [Line Items]        
Sales 2 3 5 6
Total Pharmaceutical segment sales | United States | Operating Segments | Atozet        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Alliance revenue - Adempas (2)        
Segment Reporting Information [Line Items]        
Sales 73 49 122 89
Total Pharmaceutical segment sales | United States | Operating Segments | Adempas        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Januvia        
Segment Reporting Information [Line Items]        
Sales 413 471 768 855
Total Pharmaceutical segment sales | United States | Operating Segments | Janumet        
Segment Reporting Information [Line Items]        
Sales 143 166 256 333
Total Pharmaceutical segment sales | United States | Operating Segments | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 87 136 237 285
Total Pharmaceutical segment sales | United States | Operating Segments | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 35 206 61 391
Total Pharmaceutical segment sales | United States | Operating Segments | Singulair        
Segment Reporting Information [Line Items]        
Sales 4 8 9 13
Total Pharmaceutical segment sales | United States | Operating Segments | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 4 6 12 10
Total Pharmaceutical segment sales | United States | Operating Segments | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Nasonex        
Segment Reporting Information [Line Items]        
Sales 4 (1) 10 (2)
Total Pharmaceutical segment sales | United States | Operating Segments | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 20 24 40 53
Total Pharmaceutical segment sales | United States | Operating Segments | Other pharmaceutical (3)        
Segment Reporting Information [Line Items]        
Sales 385 369 792 697
Total Pharmaceutical segment sales | International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 5,409 5,653 11,350 11,101
Total Pharmaceutical segment sales | International | Operating Segments | Keytruda        
Segment Reporting Information [Line Items]        
Sales 1,345 1,136 2,722 2,121
Total Pharmaceutical segment sales | International | Operating Segments | Alliance revenue - Lynparza (1)        
Segment Reporting Information [Line Items]        
Sales 73 45 133 74
Total Pharmaceutical segment sales | International | Operating Segments | Alliance revenue - Lenvima (1)        
Segment Reporting Information [Line Items]        
Sales 53 43 91 67
Total Pharmaceutical segment sales | International | Operating Segments | Emend        
Segment Reporting Information [Line Items]        
Sales 27 54 65 107
Total Pharmaceutical segment sales | International | Operating Segments | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 488 430 1,124 906
Total Pharmaceutical segment sales | International | Operating Segments | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 115 174 217 328
Total Pharmaceutical segment sales | International | Operating Segments | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 68 68 150 125
Total Pharmaceutical segment sales | International | Operating Segments | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 96 47 170 107
Total Pharmaceutical segment sales | International | Operating Segments | Vaqta        
Segment Reporting Information [Line Items]        
Sales 11 20 41 39
Total Pharmaceutical segment sales | International | Operating Segments | Bridion        
Segment Reporting Information [Line Items]        
Sales 117 149 274 285
Total Pharmaceutical segment sales | International | Operating Segments | Noxafil        
Segment Reporting Information [Line Items]        
Sales 67 93 154 192
Total Pharmaceutical segment sales | International | Operating Segments | Prevymis        
Segment Reporting Information [Line Items]        
Sales 35 18 68 33
Total Pharmaceutical segment sales | International | Operating Segments | Primaxin        
Segment Reporting Information [Line Items]        
Sales 63 70 114 129
Total Pharmaceutical segment sales | International | Operating Segments | Invanz        
Segment Reporting Information [Line Items]        
Sales 43 60 102 118
Total Pharmaceutical segment sales | International | Operating Segments | Cancidas        
Segment Reporting Information [Line Items]        
Sales 45 64 98 125
Total Pharmaceutical segment sales | International | Operating Segments | Cubicin        
Segment Reporting Information [Line Items]        
Sales 21 45 53 91
Total Pharmaceutical segment sales | International | Operating Segments | Zerbaxa        
Segment Reporting Information [Line Items]        
Sales 15 14 32 28
Total Pharmaceutical segment sales | International | Operating Segments | Simponi        
Segment Reporting Information [Line Items]        
Sales 191 214 406 422
Total Pharmaceutical segment sales | International | Operating Segments | Remicade        
Segment Reporting Information [Line Items]        
Sales 73 98 160 221
Total Pharmaceutical segment sales | International | Operating Segments | Belsomra        
Segment Reporting Information [Line Items]        
Sales 61 55 114 98
Total Pharmaceutical segment sales | International | Operating Segments | Isentress/Isentress HD        
Segment Reporting Information [Line Items]        
Sales 120 153 290 300
Total Pharmaceutical segment sales | International | Operating Segments | Zepatier        
Segment Reporting Information [Line Items]        
Sales 24 68 62 149
Total Pharmaceutical segment sales | International | Operating Segments | Zetia        
Segment Reporting Information [Line Items]        
Sales 138 150 285 290
Total Pharmaceutical segment sales | International | Operating Segments | Vytorin        
Segment Reporting Information [Line Items]        
Sales 37 73 86 167
Total Pharmaceutical segment sales | International | Operating Segments | Atozet        
Segment Reporting Information [Line Items]        
Sales 115 92 238 186
Total Pharmaceutical segment sales | International | Operating Segments | Alliance revenue - Adempas (2)        
Segment Reporting Information [Line Items]        
Sales 6 2 11 5
Total Pharmaceutical segment sales | International | Operating Segments | Adempas        
Segment Reporting Information [Line Items]        
Sales 57 53 113 100
Total Pharmaceutical segment sales | International | Operating Segments | Januvia        
Segment Reporting Information [Line Items]        
Sales 441 437 860 877
Total Pharmaceutical segment sales | International | Operating Segments | Janumet        
Segment Reporting Information [Line Items]        
Sales 348 366 737 730
Total Pharmaceutical segment sales | International | Operating Segments | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 44 48 90 98
Total Pharmaceutical segment sales | International | Operating Segments | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 28 34 65 68
Total Pharmaceutical segment sales | International | Operating Segments | Singulair        
Segment Reporting Information [Line Items]        
Sales 96 153 246 338
Total Pharmaceutical segment sales | International | Operating Segments | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 94 103 189 202
Total Pharmaceutical segment sales | International | Operating Segments | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 65 75 135 149
Total Pharmaceutical segment sales | International | Operating Segments | Nasonex        
Segment Reporting Information [Line Items]        
Sales 45 73 110 170
Total Pharmaceutical segment sales | International | Operating Segments | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 24 39 45 67
Total Pharmaceutical segment sales | International | Operating Segments | Other pharmaceutical (3)        
Segment Reporting Information [Line Items]        
Sales 720 837 1,500 1,589
Total Animal Health segment sales | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 1,101 1,124 2,314 2,149
Total Animal Health segment sales | Operating Segments | Livestock        
Segment Reporting Information [Line Items]        
Sales 648 671 1,386 1,282
Total Animal Health segment sales | Operating Segments | Companion Animals        
Segment Reporting Information [Line Items]        
Sales 453 453 928 867
Total Animal Health segment sales | United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 342 335 726 628
Total Animal Health segment sales | United States | Operating Segments | Livestock        
Segment Reporting Information [Line Items]        
Sales 122 145 284 261
Total Animal Health segment sales | United States | Operating Segments | Companion Animals        
Segment Reporting Information [Line Items]        
Sales 220 190 442 367
Total Animal Health segment sales | International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 759 789 1,588 1,521
Total Animal Health segment sales | International | Operating Segments | Livestock        
Segment Reporting Information [Line Items]        
Sales 526 526 1,102 1,021
Total Animal Health segment sales | International | Operating Segments | Companion Animals        
Segment Reporting Information [Line Items]        
Sales 233 263 486 500
Other segment sales (4) | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 0 48 23 87
Other segment sales (4) | United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 0 47 23 86
Other segment sales (4) | International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales $ 0 $ 0 $ 0 $ 0