&RPHULFD,QFRUSRUDWHG 6HFRQG4XDUWHU )LQDQFLDO5HYLHZ -XO\  6DIH+DUERU6WDWHPHQW Any statements in this presentation that are not historical facts are forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995. Words such as “anticipates,” “believes,” “contemplates,” “feels,” “expects,” “estimates,” “seeks,” “strives,” “plans,” “intends,” “outlook,” “forecast,” “position,” “target,” “mission,” “assume,” “achievable,” “potential,” “strategy,” “goal,” “aspiration,” “opportunity,” “initiative,” “outcome,” “continue,” “remain,” “maintain,” “on track,” “trend,” “objective,” “looks forward,” “projects,” “models” and variations of such words and similar expressions, or future or conditional verbs such as “will,” “would,” “should,” “could,” “might,” “can,” “may” or similar expressions, as they relate to Comerica or its management, are intended to identify forward-looking statements. These forward-looking statements are predicated on the beliefs and assumptions of Comerica's management based on information known to Comerica's management as of the date of this presentation and do not purport to speak as of any other date. Forward-looking statements may include descriptions of plans and objectives of Comerica's management for future or past operations, products or services, and forecasts of Comerica's revenue, earnings or other measures of economic performance, including statements of profitability, business segments and subsidiaries as well as estimates of credit trends and global stability. Such statements reflect the view of Comerica's management as of this date with respect to future events and are subject to risks and uncertainties. Should one or more of these risks materialize or should underlying beliefs or assumptions prove incorrect, Comerica's actual results could differ materially from those discussed. Factors that could cause or contribute to such differences are changes in general economic, political or industry conditions; changes in monetary and fiscal policies; operational, systems or infrastructure failures; reliance on other companies to provide certain key components of business infrastructure; cybersecurity risks; whether Comerica may achieve opportunities for revenue enhancements and efficiency improvements under the GEAR Up initiative, or changes in the scope or assumptions underlying the GEAR Up initiative; Comerica's ability to maintain adequate sources of funding and liquidity; the effects of more stringent capital requirements; declines or other changes in the businesses or industries of Comerica's customers; unfavorable developments concerning credit quality; changes in regulation or oversight; heightened legislative and regulatory focus on cybersecurity and data privacy; fluctuations in interest rates and their impact on deposit pricing; transitions away from LIBOR towards new interest rate benchmarks; reductions in Comerica's credit rating; damage to Comerica's reputation; Comerica's ability to utilize technology to efficiently and effectively develop, market and deliver new products and services; competitive product and pricing pressures among financial institutions within Comerica's markets; the interdependence of financial service companies; the implementation of Comerica's strategies and business initiatives; changes in customer behavior; management's ability to maintain and expand customer relationships; the effectiveness of methods of reducing risk exposures; the effects of catastrophic events including, but not limited to, hurricanes, tornadoes, earthquakes, fires, droughts and floods; the impacts of future legislative, administrative or judicial changes to tax regulations; any future strategic acquisitions or divestitures; management's ability to retain key officers and employees; the impact of legal and regulatory proceedings or determinations; losses due to fraud; the effects of terrorist activities and other hostilities; changes in accounting standards; the critical nature of Comerica's accounting policies; controls and procedures failures; and the volatility of Comerica’s stock price. Comerica cautions that the foregoing list of factors is not all-inclusive. For discussion of factors that may cause actual results to differ from expectations, please refer to our filings with the Securities and Exchange Commission. In particular, please refer to “Item 1A. Risk Factors” beginning on page 12 of Comerica's Annual Report on Form 10-K for the year ended December 31, 2018. Forward-looking statements speak only as of the date they are made. Comerica does not undertake to update forward-looking statements to reflect facts, circumstances, assumptions or events that occur after the date the forward-looking statements are made. For any forward-looking statements made in this presentation or in any documents, Comerica claims the protection of the safe harbor for forward-looking statements contained in the Private Securities Litigation Reform Act of 1995. 2

6HFRQG4XDUWHU5HVXOWV Revenue growth & expense discipline drove efficiency ratio under 50% &KDQJH)URP PLOOLRQVH[FHSWSHUVKDUHGDWD 4 4 4 4 4 .H\4R43HUIRUPDQFH'ULYHUV $YHUDJHORDQV $50,963 49,677 49,225 $1,286 $1,738 ƒ 6WURQJ ORDQJURZWK $YHUDJHGHSRVLWV 54,995 53,996 55,830 999 (83 ) 5 ƒ &RUHGHSRVLWVVWDEOH 1HWLQWHUHVWLQFRPH $603 606 590 $(3) $13 ƒ 3UHWD[SUHSURYLVLRQQHWUHYHQXH 3URYLVLRQIRUFUHGLWORVVHV 44 (13) (29) 57 73 H[FOXGLQJ400VHFXULWLHV ORVVLQFUHDVHG00 1RQLQWHUHVWLQFRPH 250 238 248 12 2 $GMXVWHG 250 246 248 4 2 ƒ 1HWLQWHUHVWLQFRPHDLGHGE\ORDQ 1RQLQWHUHVWH[SHQVHV 424 433 448 (9) (24) JURZWKZKLFKZDVPRUHWKDQ $GMXVWHG 424 433 437 (9) (13) RIIVHWE\KLJKHUIXQGLQJFRVWV 3URYLVLRQIRULQFRPHWD[ 87 85 93 2 (6) ƒ &UHGLWUHPDLQVVROLG3URYLVLRQ 1HWLQFRPH 298 339 326 (41) (28) GULYHQE\ORDQJURZWK (QHUJ\ UHVHUYHV (DUQLQJVSHUVKDUH $1.94 2.11 1.87 $(0.17) $0.07 $GMXVWHG 1.94 2.08 1.90 (0.14) 0.04 ƒ 6ROLGQRQLQWHUHVW LQFRPHJURZWK $YHUDJHGLOXWHGVKDUHV 153.2 159.5 173.6 (6.3) (20.4) ƒ ([SHQVHVGHFOLQHGRYHU  52( 16.41% 18.44% 16.40% ƒ 5HSXUFKDVHG00VKDUHV 52$ 1.68 1.97 1.85 UHWXUQHG00WRVKDUHKROGHUV (IILFLHQF\5DWLR 49.65 50.81 53.24 EX\EDFN GLYLGHQG 2Q19 compared to 1Q19 Ⴠ 11Q19 included $8MM loss related to repositioning of securities portfolio Ɣ 2See Reconciliation of Non-GAAP Financial Measures slide Ⴠ 3Diluted earnings per common share Ⴠ 4Return on average common shareholders’ equity Ⴠ 5Return on Average assets Ⴠ 6Noninterest expenses as a percentage of net interest income and noninterest income excluding net gains (losses) from securities and a derivative contract tied to the conversion rate of Visa Class B shares. Ⴠ 72Q19 repurchases under the share repurchase program 3 6WURQJ/RDQ*URZWK Average loans increased $1.3B, or 3% 7RWDO/RDQV $YHUDJHORDQVLQFUHDVHG% LQELOOLRQV Loan Yields 000RUWJDJH%DQNHU 51.8 00*HQHUDO0LGGOH0DUNHW 51.0 50.3 49.7 00&RPPHUFLDO5HDO(VWDWH 49.2 48.8 48.6 00(QHUJ\  003ULYDWH%DQNLQJ /RDQ\LHOGVLPSDFWHGE\ORZHU/,%25OHDVH 5.07 4.90 5.00 UHVLGXDODGMXVWPHQW PL[VKLIWLQSRUWIROLR 4.74 4.63 /RDQ&RPPLWPHQWV LQELOOLRQV 3HULRGHQG 53.1 53.2 51.1 51.8 52.9 2Q18 3Q18 4Q18 1Q19 2Q19 1Q19 2Q19 $YHUDJH%DODQFHV 3HULRGHQG 2Q18 3Q18 4Q18 1Q19 2Q19 2Q19 compared to 1Q19 4

'HSRVLWV,QFUHDVHG Average core deposits remained stable 7RWDO'HSRVLWV LQELOOLRQV Deposit Rates1 55.8 56.1 55.7 55.5 $YHUDJHGHSRVLWVLQFUHDVHG% 54.0 55.0 54.1 ƒ 1RQLQWHUHVWEHDULQJGHFOLQHG00 ƒ ,QWHUHVWEHDULQJLQFUHDVHG% ƒ f%LQFUHDVHLQEURNHUHG GHSRVLWVZKLFKSURYLGHORZFRVW IOH[LEOHIXQGLQJ /RDQWRGHSRVLWUDWLR VWDEOHDW 0.94 0.78 0.62 0.42 0.51 2Q18 3Q18 4Q18 1Q19 2Q19 1Q19 2Q19 $YHUDJH%DODQFHV 3HULRGHQG 2Q19 compared to 1Q19 Ⴠ 1Interest costs on interest-bearing deposits Ⴠ 2At 6/30/19 5 6HFXULWLHV3RUWIROLR6WDEOH Yields increased 6 basis points 6HFXULWLHV3RUWIROLR LQELOOLRQV Treasury Securities & Other Mortgage-backed Securities (MBS) Securities Yields 'XUDWLRQRI\HDUV ƒ ([WHQGVWR \HDUVXQGHUDESV 12.1 12.2 12.3 11.8 11.8 11.8 12.0 LQVWDQWDQHRXVUDWHLQFUHDVH 1HWXQUHDOL]HGSUHWD[JDLQRI00 1HWXQDPRUWL]HGSUHPLXPRI00 9.5 9.5 9.1 9.1 9.1 9.2 9.3 <LHOGVLQFUHDVHGEDVLVSRLQWV ƒ 4XDUWHUO\SD\GRZQRIf00ZDV UHSODFHGDWKLJKHU\LHOG 2.45 ƒ 5HSRVLWLRQHG%LQ7UHDVXULHV 2.35 2.39 2.12 2.17 2Q18 3Q18 4Q18 1Q19 2Q19 1Q19 2Q19 $YHUDJH%DODQFHV 3HULRGHQG 6/30/19 Ɣ 1Estimated as of 6/30/19 Ɣ 2Net unrealized pre-tax gain/loss on the available-for-sale (AFS) portfolio Ɣ 3Net unamortized premium on the MBS portfolio 6

1HW,QWHUHVW,QFRPH6WDEOH Loan growth more than offset by higher funding costs 1HW,QWHUHVW,QFRPH LQPLOOLRQV NIM $606MM 1Q19 3.79% 614 + 14MM Loans: - 0.02 606 603 590 599 + 16MM Higher balances +0.02 + 6MM 1 additional day -- -4MMLower LIBOR -0.02 -2MMLease residual adj. -0.01 - 1MM Hedges -0.01 -1MMPortfolio mix shift -- 3.79 + 3MM Securities: + 0.01 3.70 3.67 Higher yield 3.62 3.60 - 15MM Deposits: - 0.09 -8MM Higher balances -0.05 -7MM Higher rates -0.04 -5MM Wholesale funding: -0.02 Higher level $603MM 2Q19 3.67% 2Q18 3Q18 4Q18 1Q19 2Q19 2Q19 compared to 1Q19 7 &UHGLW4XDOLW\5HPDLQV6ROLG Provision reflects loan growth & decline in value of select energy assets $OORZDQFHIRU&UHGLW/RVVHV  LQPLOOLRQV ƒ 00LQQHWFKDUJHRIIV RUESV Allowance for Loan Losses as a % of Total Loans ƒ 1RQDFFUXDOORDQV ESVRIWRWDOORDQV 711 697 701 677 688 ƒ $///13/FRYHUDJH[ 1.36 1.35 1.34 ƒ 3URYLVLRQLQFUHDVHG00RYHU4 1.29 1.27 • /RDQJURZWK • 6HOHFWOLTXLGDWLQJHQHUJ\DVVHWV LPSDFWHGE\UDSLGGHFOLQHLQYDOXDWLRQV 2Q18 3Q18 4Q18 1Q19 2Q19 &ULWLFL]HG/RDQV LQPLOOLRQV $ in millions Energy Ex-Energy Total NALsNAL CriticizedCitii d as a % of fT Total t lL Loans Total PE loans $2,434 $49,367 $51,801 % of total 5% 95% 100% 1,948 1,765 1,806 1 1,670 1,548 Criticized 210 1,738 1,948 Ratio 8.6% 3.5% 3.8% Nonaccrual 84 140 224 3.6 3.8 3.5 3.4 3.1 Ratio 3.5% 0.3% 0.4% 2 254 230 221 191 224 Net charge-offs 25 8 33 Ratio N/M 0.06% 0.26% 2Q18 3Q18 4Q18 1Q19 2Q19 6/30/19 Ɣ1Criticized loans are consistent with regulatory defined Special Mention, Substandard, & Doubtful categories Ɣ 2Net credit-related charge-offs; ratio shown as a % of average loans Ɣ N/M = Not meaningful 8

1RQLQWHUHVW,QFRPH,QFUHDVHG Card fees continue to grow 1RQLQWHUHVW,QFRPH 1RQLQWHUHVWLQFRPHLQFUHDVHG00 LQPLOOLRQV H[FOXGLQJ006HFXULWLHVORVVHVLQ4 Securities losses due to repositioning 00)LGXFLDU\LQFRPH 00&DUG 254 248 250 246 250 00%DQNRZQHGOLIHLQVXUDQFH 20 8 234 238  00'HIHUUHG&RPSRIIVHWLQQRQLQWHUHVWH[SHQVH *URZLQJ&DUG)HHV LQPLOOLRQV 65 64 63 60 61 2Q18 3Q18 4Q18 1Q19 2Q19 2Q18 3Q18 4Q18 1Q19 2Q19 2Q19 compared to 1Q19 Ɣ 1See Reconciliation of Non-GAAP Financial Measures slide 9 1RQLQWHUHVW([SHQVH'HFOLQHG Disciplined cost management drives efficiency ratio1 under 50% 1RQLQWHUHVW([SHQVH LQPLOOLRQV Restructuring Efficiency Ratio 1RQLQWHUHVWH[SHQVHGHFOLQHG00  006DODULHV EHQHILWV 448 452 448 4DQQXDOVWRFNFRPS  433 11 12 14 424 KLJKHUSD\UROOWD[HV 440 0HULWLQFUHDVHV 437 434 433 424 2QHDGGLWLRQDOGD\  'HIHUUHG&RPSRIIVHWLQQRQLQWHUHVWLQFRPH 00$GYHUWLVLQJ 00/HJDO4UHFRYHULHV 002XWVLGHSURFHVVLQJ 53.2% 52.9% 51.9% 50.8% 49.7% 2Q18 3Q18 4Q18 1Q19 2Q19 2Q19 compared to 1Q19 Ⴠ 1Noninterest expenses as a percentage of net interest income & noninterest income excluding net gains (losses) from securities & a derivative contract tied to the conversion rate of Visa Class B shares Ɣ 2See Reconciliation of Non-GAAP 3 Financial Measures slide Ɣ Included in other noninterest expenses 10

$FWLYH&DSLWDO0DQDJHPHQW Returning excess capital at a fast pace 5HWXUQHG00WRVKDUHKROGHUV 5HGXFWLRQLQ6KDUHV<< ƒ 00VKDUHVUHSXUFKDVHG00 ,QPLOOLRQV DYHUDJHGLOXWHGVKDUHV 174 170 164 &RQWLQXHWRDFWLYHO\PDQDJHFDSLWDO 160 153 ƒ 7DUJHWf&(7E\)<( ƒ &DUHIXOFRQVLGHUDWLRQJLYHQWR • (DUQLQJVJHQHUDWLRQ • &DSLWDOQHHGVLHORDQJURZWK • 0DUNHWFRQGLWLRQV 2Q18 3Q18 4Q18 1Q19 2Q19 &DSLWDO3RVLWLRQ5HPDLQV6ROLG&(7 6KDUHKROGHU3D\RXW 'LYLGHQGV ,QSHUFHQWDJHSRLQWV LQPLOOLRQV 3HU6KDUH Dividends 11.89 11.68 11.14 10.78 Share Repurchases 0.67 10.19 525 100 0.34 425 227 58 169 2Q18 3Q18 4Q18 1Q19 2Q19 3 2Q18 2Q19 2Q18 2Q19 6/30/19 Ⴠ 1Outlook as of 7/17/19 Ⴠ 2Shares repurchased under share repurchase program Ⴠ 3Estimated 11 ,QWHUHVW5DWH(QYLURQPHQW Focus on continued careful management of deposit costs (VWLPDWHG1HW,QWHUHVW,QFRPH +HGJLQJ$FWLYLW\ ,Q'LIIHUHQW5DWH6FHQDULRV $QQXDOPRQWK6HQVLWLYLWLHV ƒ %SD\IORDWLQJUHFHLYHIL[HGKHGJHV %DVHGRQ6WDQGDUG0RGHO:LWK • \HDUDYHUDJHWHUP 'HSRVLW%HWD$VVXPSWLRQV$OWHUHG • DYHUDJHIL[HGUDWH LQPLOOLRQV ƒ ([SHFWWRUHGXFHWKHXQIDYRUDEOHLPSDFW RQQHWLQWHUHVWLQFRPHIURPDESV ~60 GURSLQUDWHVESVRQDYHUDJHE\ f00 %HQHILFLDO'HSRVLW0L[ LQELOOLRQV4$YHUDJH • &RPPHUFLDORIQRQLQWHUHVWEHDULQJ ~60 • 5HWDLORILQWHUHVWEHDULQJ ~80 ~90 Retail Commercial Noninterest- Noninterest- Down 50 bps Down 50 bps Down 50 bps Up 100 bps bearing bearing & 10% deposit & 25% deposit (25 bps shock) (50 bps on 8% Total 40% Beta Beta 50% deposit average) Retail $55.0 Commercial Beta Interest- Interest- bearing bearing3 29% 23% 6/30/19 Ɣ Outlook as of 7/17/19 Ⴠ 1For methodology see the Company’s Form 10-Q, as filed with the SEC. Estimates are based on simulation modeling analysis. Ⴠ 2YTD 6/30/19 Ⴠ 3Includes Finance/Other 12

0DQDJHPHQW2XWORRNIRU)< $VVXPLQJFRQWLQXDWLRQRIFXUUHQWHFRQRPLFHQYLURQPHQW UDWHVDVRI $YHUDJH • 8SGDWHGEHWWHUWKDQH[SHFWHGJURZWK<7'ZLWKQRUPDOVHDVRQDOLW\IRUUHPDLQGHURI\HDU  /RDQV • 0DLQWDLQSULFLQJ XQGHUZULWLQJGLVFLSOLQH $YHUDJH • 8SGDWHG FRLQFLGHQWZLWKORDQJURZWKFXVWRPHUVXVLQJFDVKLQWKHLUEXVLQHVVHV  'HSRVLWV • &RQWLQXHGIRFXVRQUHODWLRQVKLSDSSURDFKWRDWWUDFWDQGUHWDLQFXVWRPHUV 1HW,QWHUHVW • 8SGDWHG GHFUHDVHLQ/,%25EDVHGRQUDWHV JUHDWHUIXQGLQJQHHGV  • 1HWEHQHILWIURPKLJKHUUDWHVORDQJURZWK VHFXULWLHVSRUWIROLRUHSRVLWLRQLQJ ,QFRPH • +HDGZLQGVKLJKHUZKROHVDOHIXQGLQJGHSRVLWPL[VKLIW ORZHUQRQDFFUXDOUHFRYHULHV • 8SGDWHG00SHUTXDUWHUIRUWKHUHPDLQGHURIWKH\HDU 3URYLVLRQ ESV • 6ROLGFUHGLWTXDOLW\FRQWLQXHV1HWFKDUJHRIIVWRUHPDLQORZ 1RQLQWHUHVW • ,QFUHDVHVLQFDUGDQGILGXFLDU\IHHV  ,QFRPH • 3DUWO\RIIVHWE\ORZHUGHULYDWLYHV GHSRVLWVHUYLFHFKDUJHV 1RQLQWHUHVW • 6WDEOHH[FOXGLQJ)<00LQUHVWUXFWXULQJH[SHQVHV  • /RZHUFRPSHQVDWLRQLQFHQWLYHVSDUWO\RIIVHWE\PHULWSHQVLRQ )',&H[SHQVH00 ([SHQVHV • 5LVHLQRXWVLGHSURFHVVLQJWLHGWRUHYHQXHWHFKQRORJ\FRVWV LQIODWLRQDU\SUHVVXUHV • ([FOXGHVLPSDFWIURPHPSOR\HHVWRFNWUDQVDFWLRQV 7D[5DWH f • )<LQFOXGHG00LQGLVFUHWHEHQHILWV &DSLWDO • 8SGDWHG WDUJHWE\)<(UHIOHFWVSRWHQWLDOVXVWDLQHGSDFHRIORDQJURZWK f • 6WURQJSHUIRUPDQFH H[FHVVFDSLWDOGULYHEX\EDFNZKLFKLVDVLJQLILFDQWFRQWULEXWRUWR 0DQDJHPHQW &(77DUJHW LQFUHDVLQJHDUQLQJVSHUVKDUH Outlook as of 7/17/19 Ⴠ FY19 outlook compared to FY18 actual results based on GAAP reported amounts 13 Appendix

$YHUDJH/RDQVE\%XVLQHVVDQG0DUNHW %\/LQHRI%XVLQHVV 4 4 4 %\0DUNHW 4 4 4 Middle Market Michigan $12.7 $12.6 $12.6 General $12.4 $12.0 $12.0 Energy 2.5 2.3 1.8 California 18.9 18.8 18.4 National Dealer Services 7.9 7.8 7.4 Entertainment 0.8 0.8 0.7 Texas 10.7 10.3 9.9 Tech. & Life Sciences 1.3 1.3 1.4 Other Markets1 8.7 8.1 8.3 Equity Fund Services 2.6 2.6 2.4 Environmental Services 1.2 1.2 1.0 TOTAL $51.0 $49.7 $49.2 Total Middle Market $28.7 $28.0 $26.8 Corporate Banking US Banking 3.0 3.0 3.1 /RDQ3RUWIROLR LQELOOLRQV4 3HULRGHQG International 1.3 1.3 1.3 Commercial Real Estate 5.5 5.3 5.3 Fixed Rate Mortgage Banker Finance 2.0 1.3 1.8 9% Small Business 3.5 3.5 3.7 BUSINESS BANK $44.0 $42.5 $42.0 Prime-based Total 30-Day Retail Banking 2.1 2.1 2.1 15% $51.8 LIBOR RETAIL BANK $2.1 $2.1 $2.1 70% 60-Day+ Private Banking 4.9 5.0 5.1 LIBOR WEALTH MANAGEMENT $4.9 $5.0 $5.1 6% TOTAL $51.0 $49.7 $49.2 $ in billions Ⴠ Totals shown above may not foot due to rounding Ⴠ 1Other Markets includes Florida, Arizona, the International Finance Division and businesses that have a significant presence outside of the three primary geographic markets 15 $YHUDJH'HSRVLWVE\%XVLQHVVDQG0DUNHW %\/LQHRI%XVLQHVV 4 4 4 %\0DUNHW 4 4 4 Middle Market Michigan $19.8 $19.9 $20.9 General $13.4 $13.3 $13.3 Energy 0.4 0.5 0.5 California 16.3 16.2 16.6 National Dealer Services 0.3 0.3 0.3 Texas 8.7 8.7 9.0 Entertainment 0.1 0.1 0.1 1 Tech. & Life Sciences 4.7 5.0 5.1 Other Markets 7.8 7.9 8.1 Equity Fund Services 0.8 0.8 0.9 Finance/Other2 2.4 1.3 1.2 Environmental Services 0.2 0.2 0.1 TOTAL $55.0 $54.0 $55.8 Total Middle Market $19.9 $20.1 $20.4 Corporate Banking US Banking 1.7 1.8 2.1 International 1.6 1.6 1.9 ƒ 0LGGOH0DUNHW6HUYLQJFRPSDQLHVZLWK Commercial Real Estate 1.5 1.5 1.5 UHYHQXHVJHQHUDOO\EHWZHHQ00 Mortgage Banker Finance 0.7 0.6 0.7 Small Business 2.9 2.9 3.2 ƒ &RUSRUDWH%DQNLQJ6HUYLQJFRPSDQLHV DQGWKHLU86EDVHGVXEVLGLDULHVZLWK BUSINESS BANK $28.3 $28.5 $29.7 UHYHQXHVJHQHUDOO\RYHU00 Retail Banking 20.6 20.5 21.0 ƒ 6PDOO%XVLQHVV6HUYLQJFRPSDQLHVZLWK RETAIL BANK $20.6 $20.5 $21.0 UHYHQXHVJHQHUDOO\XQGHU00 Private Banking 3.5 3.5 3.6 WEALTH MANAGEMENT $3.7 $3.8 $3.9 Finance/Other2 2.4 1.3 1.2 TOTAL $55.0 $54.0 $55.8 $ in billions Ⴠ Totals shown above may not foot due to rounding Ⴠ 1Other Markets includes Florida, Arizona, the International Finance Division and businesses that have a significant presence outside of the three primary geographic markets Ⴠ 2Finance/Other includes items not directly associated with the geographic markets or the three major business segments 16

&RPPHUFLDO5HDO(VWDWH/LQHRI%XVLQHVV Long history of working with well established, proven developers &5(E\3URSHUW\7\SH &5(E\0DUNHW LQPLOOLRQV3HULRGHQG LQPLOOLRQV3HULRGHQGEDVHGRQORFDWLRQRISURSHUW\ Retail Michigan 10% Commercial Office 5% 13% 8% Single Family Other 6% 15% Total Other Total California 5% Multifamily $4,833 $4,833 46% 50% Land Carry 5% Texas 34% Multi use 3% &UHGLW4XDOLW\ &5(E\/RDQ7\SH LQPLOOLRQV3HULRGHQG 4 4 4 LQPLOOLRQV3HULRGHQG 4 4 &ULWLFL]HG $84 $84 $106 5HDO(VWDWH &RQVWUXFWLRQ $2,888 53% $2,936 53% 5DWLR 1.6% 1.5% 1.9% &RPPHUFLDO0RUWJDJHV 1,739 32% 1,897 34% 1RQDFFUXDO $3 $2 $2 $4,627 85% $4,833 87% 5DWLR 0.06% 0.04% 0.04% &RPPHUFLDO 2WKHU 788 15% 754 13% 1HWFKDUJHRIIV UHFRYHULHV -0- -0- -0- 7RWDO $5,415 100% $5,587 100% 6/30/19 Ⴠ 1Excludes CRE line of business loans not secured by real estate Ⴠ 2Criticized loans are consistent with regulatory defined Special Mention, Substandard & Doubtful categories 17 (QHUJ\/LQHRI%XVLQHVV 30+ years industry experience (QHUJ\/LQHRI%XVLQHVV/RDQV ƒ )RFXVRQIXOOUHODWLRQVKLSVZLWKODUJHU LQPLOOLRQV3HULRGHQG VRSKLVWLFDWHG( 3FRPSDQLHVDFFHVVWRD MidstreamMidstream ServicesServices ExplorationExploration &&P Productionroduction YDULHW\RIFDSLWDOVRXUFHVKHGJLQJ GLYHUVH JHRJUDSKLFIRRWSULQW 2,385 2,434 ƒ /RDQJURZWKGULYHQE\UHGXFHGFDSLWDO 2,163 PDUNHWDFWLYLW\DVZHOODVKLJKHUXWLOL]DWLRQ ƒ &KDUJHRIIV QRQDFFUXDOORDQVLQFUHDVHG 1,832 GXHWRVHOHFWOLTXLGDWLQJHQHUJ\DVVHWVMixed 1,734 LPSDFWHGE\UDSLGGHFOLQHLQYDOXDWLRQV18% 1,857 1,897 (QHUJ\/LQHRI%XVLQHVV 1,771 &ULWLFL]HG/RDQV 1,499 LQPLOOLRQV 1,400 NALs 319 269 240 205 210 75 80 94 91 100 453 457 243 233 298 84 60 53 48 33 2Q18 3Q18 4Q18 1Q19 2Q19 2Q18 3Q18 4Q18 1Q19 2Q19 6/30/19 Ɣ 1Criticized loans are consistent with regulatory defined Special Mention, Substandard & Doubtful categories 18

0RUWJDJH%DQNHU)LQDQFH 50+ years experience with reputation for consistent, reliable approach $YHUDJH/RDQV ƒ 3URYLGHZDUHKRXVHILQDQFLQJEULGJHIURP LQPLOOLRQV UHVLGHQWLDOPRUWJDJHRULJLQDWLRQWRVDOHWR Actual MBA Mortgage Origination Volumes 1,2 HQGPDUNHW ƒ ([WHQVLYHEDFNURRPSURYLGHVFROODWHUDO 2,544 2,352 2,145 2,136 2,089 2,044 PRQLWRULQJDQGFXVWRPHUVHUYLFH 1,974 1,961 1,861 1,784 1,780 1,742 1,677 1,674 1,450 1,435 ƒ )RFXVRQIXOOEDQNLQJUHODWLRQVKLSV 1,335 ƒ *UDQXODUSRUWIROLRZLWKfUHODWLRQVKLSV ƒ 8QGHUO\LQJPRUWJDJHVDUHW\SLFDOO\UHODWHG 2Q15 3Q15 4Q15 1Q16 2Q16 3Q16 4Q16 1Q17 2Q17 3Q17 4Q17 1Q18 2Q18 3Q18 4Q18 1Q19 2Q19 WRKRPHSXUFKDVHVDVRSSRVHGWR 0%$0RUWJDJH2ULJLQDWLRQV)RUHFDVW UHILQDQFHV LQELOOLRQV $VRI4 Purchase Refinance • &RPHULFDSXUFKDVH 501 515 460 • ,QGXVWU\SXUFKDVH 396 338 ƒ 6WURQJFUHGLWTXDOLW\ • 1RFKDUJHRIIVVLQFH ƒ 3HULRGHQGORDQV% 2Q19 3Q19 4Q19 1Q20 2Q20 6/30/19 Ɣ 1Source: Mortgage Bankers Association (MBA) Mortgage Finance Forecast as of 6/19/19; 2Q19 estimated Ɣ 2$ in billions 19 1DWLRQDO'HDOHU6HUYLFHV 65+ years of floor plan lending )UDQFKLVH'LVWULEXWLRQ ƒ 7RSWLHUVWUDWHJ\ %DVHGRQSHULRGHQGORDQRXWVWDQGLQJV Honda/Acura ƒ )RFXVRQn0HJD'HDOHU|ILYHRUPRUH 16% GHDOHUVKLSVLQJURXS Toyota/Lexus 16% Ford ƒ 6WURQJFUHGLWTXDOLW\ 9% ƒ 5REXVWPRQLWRULQJRIFRPSDQ\LQYHQWRU\ DQGSHUIRUPDQFH GM 1 Total Other 8% 10% $7.8B $YHUDJH/RDQV Fiat/Chrysler LQELOOLRQV 10% Floor Plan Mercedes 7.9 7.8 7.4 7.4 7.3 Other Asian 7.1 7.1 7.0 3% 6.9 6.8 6.6 6.5 6.3 12% 6.2 6.2 6.0 Nissan/ Infiniti 5.9 Other European 5% 11% *HRJUDSKLF'LVSHUVLRQ 4.5 4.4 4.3 4.2 4.1 4.1 4.1 4.0 4.0 4.0 3.9 3.8 3.8 3.7 3.7 3.6 California 58% Texas 6% 3.5 Michigan 24% Other 12% 2Q15 3Q15 4Q15 1Q16 2Q16 3Q16 4Q16 1Q17 2Q17 3Q17 4Q17 1Q18 2Q18 3Q18 4Q18 1Q19 2Q19 6/30/19 Ɣ 1Other includes obligations where a primary franchise is indeterminable (rental car and leasing companies, heavy truck, recreational vehicles, and non-floor plan loans) 20

7HFKQRORJ\DQG/LIH6FLHQFHV (TXLW\)XQG6HUYLFHV Deep expertise & strong relationships with top-tier investors 7HFKQRORJ\ /LIH6FLHQFHV$YJ/RDQV (TXLW\)XQG6HUYLFHV$YJ/RDQV LQPLOOLRQV LQPLOOLRQV 22,579579 2,539 26322,632 26022,602 1,416 2,432 1,396 1,353 1,323 1,305 2Q18 3Q18 4Q18 1Q19 2Q19 2Q18 3Q18 4Q18 1Q19 2Q19 ƒ fFXVWRPHUV ƒ fFXVWRPHUV ƒ 0DQDJHFRQFHQWUDWLRQWRQXPHURXVYHUWLFDOV ƒ &RPPHUFLDOEDQNLQJVHUYLFHVIRUYHQWXUH WRHQVXUHZLGHO\GLYHUVLILHGSRUWIROLR FDSLWDO SULYDWHHTXLW\ILUPV ƒ &ORVHO\PRQLWRUFDVKEDODQFHV PDLQWDLQ UREXVWEDFNURRPRSHUDWLRQ ƒ %ULGJHILQDQFLQJIRUFDSLWDOFDOOV ƒ RIILFHVWKURXJKRXW86 &DQDGD ƒ 6WURQJFUHGLWSURILOH Customer Segment ~50% ~20% ~20% ~10% Overview 1 Growth Leveraged Finance Early Stage Late Stage 6/30/19 Ɣ 1Based on 2Q19 period-end loans totaling $1.3B 21 7HFK9LVLRQ  Preparing for a new age in banking 6WUHQJWKHQLQJ2XU&RUH ƒ 3ODWIRUP DSSPRGHUQL]DWLRQ ƒ &\EHUVHFXULW\ULVN FRPSOLDQFHHQKDQFHPHQW ƒ *($58SKHOSHGSRVLWLRQRXUV\VWHPV  ƒ 7DOHQW FXOWXUHGHYHORSPHQW WDOHQWIRUWKHIXWXUH 7UDQVIRUPLQJ2XU)XWXUH ƒ 7HFKQRORJ\VDYLQJVDUHEHLQJUHLQYHVWHG ƒ (PEUDFHHPHUJLQJWHFKQRORJLHV ZKLFKKHOSVPRGHUDWHULVLQJLQYHVWPHQW ƒ &RQWLQXRXVRSWLPL]DWLRQ GHPDQG ƒ $3,VGDWD DGYDQFHGDQDO\WLFV ƒ $JLOH GLJLWDOGHOLYHU\ ƒ /HYHUDJLQJWKLUGSDUWLHVWRNHHSSDFHZLWK HYROYLQJ HPHUJLQJWHFKQRORJLHV ([DPSOHVRI,QLWLDWLYHV ƒ )RFXVVKLIWHGWRLQFUHDVLQJFDSDFLW\ ƒ DSSOLFDWLRQVPLJUDWHGWRFORXG GULYLQJUHYHQXHJURZWKUHGXFLQJFRVWV  ƒ %RWVGHSOR\HGIRUKLJKYROXPHWDVNV LPSURYLQJHIILFLHQF\ ƒ 'LJLWDOL]LQJHQWLUHFRPPHUFLDOOHQGLQJSURFHVV ƒ &XVWRPHU5HODWLRQVKLS0DQDJHPHQWSODWIRUP ƒ 'DWD/DNHSODWIRUP ƒ $,0/%RWDVVLVWHGKXPDQDGYLFH ƒ %ORFNFKDLQHQDEOHGFRPSXWLQJ ƒ 7HOOHUSODWIRUPUHSODFHPHQW ƒ 5HDOWLPHFRPPHUFLDOSD\PHQWV 1API: Application Program Interface 22

+ROGLQJ&RPSDQ\'HEW5DWLQJ 6HQLRU8QVHFXUHG/RQJ7HUP,VVXHU5DWLQJ 0RRG\bV 6 3 )LWFK %% 7 $ $ $ &XOOHQ )URVW $ $  0 7%DQN $ $ $ &RPHULFD $ %%% $ %2. )LQDQFLDO&RUSRUDWLRQ $ %%% $ +XQWLQJWRQ %DD %%% $ )LIWK 7KLUG %DD %%% $ 3HHU%DQNV .H\&RUS %DD %%% $ 6XQ7UXVW %DD %%% $ 5HJLRQV)LQDQFLDO %DD %%% %%% =LRQV%DQFRUSRUDWLRQ %DD %%% %%% )LUVW+RUL]RQ1DWLRQDO&RUS %DD %%% %%% 86%DQFRUS $ $ $$ -30RUJDQ $ $ $$ %DQNRI$PHULFD $ $ $ :HOOV)DUJR &RPSDQ\ $ $ $ /DUJH%DQNV 31&)LQDQFLDO6HUYLFHV*URXS $ $ $ As of 7/10/19 Ⴠ Source: S&P Global Market Intelligence Ⴠ Debt Ratings are not a recommendation to buy, sell, or hold securities 23 5HFRQFLOLDWLRQRI1RQ*$$3)LQDQFLDO0HDVXUHV (dollar amounts in millions, except per share data) 2Q19 1Q19 2Q18 (dollar amounts in millions, except per share data) 2Q19 1Q19 2Q18 Noninterest Income: Net Income: Noninterest income $250 $238 $248 Net income $298 $339 $326 Securities repositioning — 8 — Securities repositioning, net of tax — 6 — Adjusted noninterest income $250 $246 $248 Restructuring charges, net of tax — — 9 Noninterest Expenses: Discrete tax items — (11) (3) Noninterest expenses $424 $433 $448 Adjusted net income $298 $334 $332 Restructuring charges — — (11) Diluted Earnings per Common Share: Adjusted noninterest expenses $424 $433 $437 Diluted earnings per common share $1.94 $2.11 $1.87 Pre-tax Income: Securities repositioning, net of tax — 0.04 — Pre-tax income $385 $424 $419 Restructuring charges, net of tax — — 0.05 Securities repositioning — 8 — Discrete tax items — (0.07) (0.02) Restructuring charges — — 11 Adjusted diluted earnings per common share $1.94 $2.08 $1.90 Adjusted pre-tax income $385 $432 $430 • Securities repositioning refers to 1Q19 losses incurred on the sale of Provision for Income Taxes: approximately $1 billion of treasury securities that were replaced by higher- Provision for income taxes: $87 $85 $93 yielding treasuries with a similar duration of 4 years. Tax on securities repositioning — 2 — Tax on restructuring charges — — 2 • Discrete tax items include the tax benefit from employee stock Discrete tax items — 11 3 transactions. Adjusted provision for income taxes $87 $98 $98 Comerica believes non-GAAP measures are meaningful because they reflect adjustments commonly made by management, investors, regulators and analysts to evaluate our performance trends. Comerica believes the adjusted data shown above and in this presentation provides a greater understanding of ongoing operations and enhances the comparability of results with prior periods. 24