EXHIBIT 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the Registration Statement (Form S-8) pertaining to the Comerica Incorporated Preferred Savings Plan of our reports (a) dated February 14, 2018, with respect to the consolidated financial statements of Comerica Incorporated, and the effectiveness of internal control over financial reporting of Comerica Incorporated included in its Annual Report (Form 10-K) and (b) dated May 31, 2018, with respect to the financial statements and schedule of the Comerica Incorporated Preferred Savings Plan included in the Plan's Annual Report (Form 11-K), both for the year ended December 31, 2017, filed with the Securities and Exchange Commission.

/s/ Ernst & Young LLP

Dallas, Texas

November 7, 2018