X0101 EFFECT 33 LIVE 2018-04-30 16:30:00

N-4

0000278360 GENERAL AMERICAN SEPARATE ACCOUNT TWO 333-224515 S000004948 GENERAL AMERICAN SEPARATE ACCOUNT TWO C000013364 GENERAL AMERICAN SEPARATE ACCOUNT TWO S000004948 GENERAL AMERICAN SEPARATE ACCOUNT TWO C000202484 GenAm SA 2