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Basis of Presentation and Summary of Significant Accounting Policies (Details) - shares
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Potential shares excluded from diluted net loss per share 26,169,530 19,851,451
Options to Purchase Common Stock [Member]    
Potential shares excluded from diluted net loss per share 15,841,000 15,081,000
Convertible Preferred Stock [Member]    
Potential shares excluded from diluted net loss per share 4,828,530 4,828,530
Warrants to Purchase Common Stock [Member]    
Potential shares excluded from diluted net loss per share 5,500,000 4,500,000
Common Stock Subject to Repurchase [Member]    
Potential shares excluded from diluted net loss per share (507,079)