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value="Sedol"/></identifiers><balance>4638121</balance><units>NS</units><curCd>USD</curCd><valUSD>356625124</valUSD><pctVal>2.154</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Danaher Corp</name><lei>S4BKK9OTCEWQ3YHPFM11</lei><title>Danaher Corp</title><cusip>235851102</cusip><identifiers><isin value="US2358511028"/><ticker value="DHR US"/><other otherDesc="2250870" value="Sedol"/></identifiers><balance>1945622</balance><units>NS</units><curCd>USD</curCd><valUSD>482708818</valUSD><pctVal>2.916</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Deere &amp; Co</name><lei>PWFTNG3EI0Y73OXWDH08</lei><title>Deere &amp; Co</title><cusip>244199105</cusip><identifiers><isin value="US2441991054"/><ticker value="DE US"/><other otherDesc="2261203" value="Sedol"/></identifiers><balance>1203496</balance><units>NS</units><curCd>USD</curCd><valUSD>454175320</valUSD><pctVal>2.743</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Meta Platforms Inc</name><lei>BQ4BKCS1HXDV9HN80Z93</lei><title>Meta Platforms Inc - Class A</title><cusip>30303M102</cusip><identifiers><isin value="US30303M1027"/><ticker value="META US"/><other otherDesc="B7TL820" value="Sedol"/></identifiers><balance>2543924</balance><units>NS</units><curCd>USD</curCd><valUSD>763711424</valUSD><pctVal>4.613</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Freeport-McMoRan Inc</name><lei>549300IRDTHJQ1PVET45</lei><title>FREEPORT-MCMORAN INC</title><cusip>35671D857</cusip><identifiers><isin value="US35671D8570"/><ticker value="FCX US"/><other otherDesc="2352118" value="Sedol"/></identifiers><balance>4296175</balance><units>NS</units><curCd>USD</curCd><valUSD>160204366</valUSD><pctVal>0.968</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>LVMH Moet Hennessy Louis Vuitt</name><lei>IOG4E947OATN0KJYSD45</lei><title>LVMH Moet Hennessy Louis Vuitton SE</title><cusip>F58485115</cusip><identifiers><isin value="FR0000121014"/><ticker value="MC FP"/><other otherDesc="4061412" value="Sedol"/></identifiers><balance>370226</balance><units>NS</units><currencyConditional curCd="EUR" exchangeRt="0.94598"/><valUSD>279270005</valUSD><pctVal>1.687</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>FR</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Howmet Aerospace Inc</name><lei>549300HO5WFZUT5N2T22</lei><title>Howmet Aerospace Inc</title><cusip>443201108</cusip><identifiers><isin value="US4432011082"/><ticker value="HWM US"/><other otherDesc="BKLJ8V2" value="Sedol"/></identifiers><balance>7139330</balance><units>NS</units><curCd>USD</curCd><valUSD>330194013</valUSD><pctVal>1.994</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Illumina Inc</name><lei>SQ95QG8SR5Q56LSNF682</lei><title>ILLUMINA INC</title><cusip>452327109</cusip><identifiers><isin value="US4523271090"/><ticker value="ILMN US"/><other otherDesc="2613990" value="Sedol"/></identifiers><balance>1799703</balance><units>NS</units><curCd>USD</curCd><valUSD>247063228</valUSD><pctVal>1.492</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>JPMorgan Chase &amp; Co</name><lei>8I5DZWZKVSZI1NUHU748</lei><title>JPMorgan Chase &amp; Co</title><cusip>46625H100</cusip><identifiers><isin value="US46625H1005"/><ticker value="JPM US"/><other otherDesc="2190385" value="Sedol"/></identifiers><balance>1870525</balance><units>NS</units><curCd>USD</curCd><valUSD>271263536</valUSD><pctVal>1.638</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Madrigal Pharmaceuticals Inc</name><lei>549300CHIMT2EUSNJB60</lei><title>Madrigal Pharmaceuticals Inc</title><cusip>558868105</cusip><identifiers><isin value="US5588681057"/><ticker value="MDGL US"/><other otherDesc="BD59BS7" value="Sedol"/></identifiers><balance>415101</balance><units>NS</units><curCd>USD</curCd><valUSD>60621350</valUSD><pctVal>0.366</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Marvell Technology Inc</name><lei>N/A</lei><title>Marvell Technology Inc</title><cusip>573874104</cusip><identifiers><isin value="US5738741041"/><ticker value="MRVL US"/><other otherDesc="BNKJSM5" value="Sedol"/></identifiers><balance>3233736</balance><units>NS</units><curCd>USD</curCd><valUSD>175042130</valUSD><pctVal>1.057</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Mastercard Inc</name><lei>AR5L2ODV9HN37376R084</lei><title>Mastercard Inc</title><cusip>57636Q104</cusip><identifiers><isin value="US57636Q1040"/><ticker value="MA US"/><other otherDesc="B121557" value="Sedol"/></identifiers><balance>2610359</balance><units>NS</units><curCd>USD</curCd><valUSD>1033467232</valUSD><pctVal>6.242</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Microsoft Corp</name><lei>INR2EJN1ERAN0W5ZP974</lei><title>MICROSOFT CORP</title><cusip>594918104</cusip><identifiers><isin value="US5949181045"/><ticker value="MSFT US"/><other otherDesc="2588173" value="Sedol"/></identifiers><balance>5428383</balance><units>NS</units><curCd>USD</curCd><valUSD>1714011932</valUSD><pctVal>10.353</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>NVIDIA Corp</name><lei>549300S4KLFTLO7GSQ80</lei><title>NVIDIA Corp</title><cusip>67066G104</cusip><identifiers><isin value="US67066G1040"/><ticker value="NVDA US"/><other otherDesc="2379504" value="Sedol"/></identifiers><balance>1706285</balance><units>NS</units><curCd>USD</curCd><valUSD>742216912</valUSD><pctVal>4.483</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Procter &amp; Gamble Co/The</name><lei>2572IBTT8CCZW6AU4141</lei><title>Procter &amp; Gamble Co</title><cusip>742718109</cusip><identifiers><isin value="US7427181091"/><ticker value="PG US"/><other otherDesc="2704407" value="Sedol"/></identifiers><balance>1184856</balance><units>NS</units><curCd>USD</curCd><valUSD>172823096</valUSD><pctVal>1.044</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Progressive Corp/The</name><lei>529900TACNVLY9DCR586</lei><title>Progressive Corp/The</title><cusip>743315103</cusip><identifiers><isin value="US7433151039"/><ticker value="PGR US"/><other otherDesc="2705024" value="Sedol"/></identifiers><balance>2451970</balance><units>NS</units><curCd>USD</curCd><valUSD>341559421</valUSD><pctVal>2.063</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Rivian Automotive Inc</name><lei>N/A</lei><title>Rivian Automotive Inc - Class A</title><cusip>76954A103</cusip><identifiers><isin value="US76954A1034"/><ticker value="RIVN US"/><other otherDesc="BL98841" value="Sedol"/></identifiers><balance>4261047</balance><units>NS</units><curCd>USD</curCd><valUSD>103458221</valUSD><pctVal>0.625</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Sherwin-Williams Co/The</name><lei>Z15BMIOX8DDH0X2OBP21</lei><title>Sherwin-Williams Co</title><cusip>824348106</cusip><identifiers><isin value="US8243481061"/><ticker value="SHW US"/><other otherDesc="2804211" value="Sedol"/></identifiers><balance>725720</balance><units>NS</units><curCd>USD</curCd><valUSD>185094886</valUSD><pctVal>1.118</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>TJX Cos Inc/The</name><lei>V167QI9I69W364E2DY52</lei><title>TJX Cos Inc</title><cusip>872540109</cusip><identifiers><isin value="US8725401090"/><ticker value="TJX US"/><other otherDesc="2989301" value="Sedol"/></identifiers><balance>3459785</balance><units>NS</units><curCd>USD</curCd><valUSD>307505691</valUSD><pctVal>1.857</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Texas Instruments Inc</name><lei>WDJNR2L6D8RWOEB8T652</lei><title>TEXAS INSTRUMENTS INC</title><cusip>882508104</cusip><identifiers><isin value="US8825081040"/><ticker value="TXN US"/><other otherDesc="2885409" value="Sedol"/></identifiers><balance>1679032</balance><units>NS</units><curCd>USD</curCd><valUSD>266982878</valUSD><pctVal>1.613</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Janus Henderson US Holdings Inc</name><lei>8T2ZO87FU1KVPZIG9I59</lei><title>Janus Henderson Cash Liquidity Fund</title><cusip>N/A</cusip><identifiers><isin value="DU0000100962"/></identifiers><balance>736386350</balance><units>NS</units><curCd>USD</curCd><valUSD>736607266</valUSD><pctVal>4.449</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>PF</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>UnitedHealth Group Inc</name><lei>549300GHBMY8T5GXDE41</lei><title>UnitedHealth Group Inc</title><cusip>91324P102</cusip><identifiers><isin value="US91324P1021"/><ticker value="UNH US"/><other otherDesc="2917766" value="Sedol"/></identifiers><balance>1125313</balance><units>NS</units><curCd>USD</curCd><valUSD>567371561</valUSD><pctVal>3.427</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Workday Inc</name><lei>549300J0DYC0N31V7G13</lei><title>Workday Inc</title><cusip>98138H101</cusip><identifiers><isin value="US98138H1014"/><ticker value="WDAY US"/><other otherDesc="B8K6ZD1" value="Sedol"/></identifiers><balance>2874726</balance><units>NS</units><curCd>USD</curCd><valUSD>617634881</valUSD><pctVal>3.731</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Eaton Corp PLC</name><lei>549300VDIGTMXUNT7H71</lei><title>Eaton Corp PLC</title><cusip>G29183103</cusip><identifiers><isin value="IE00B8KQN827"/><ticker value="ETN US"/><other otherDesc="B8KQN82" value="Sedol"/></identifiers><balance>579879</balance><units>NS</units><curCd>USD</curCd><valUSD>123676593</valUSD><pctVal>0.747</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Linde PLC</name><lei>5299003QR1WT0EF88V51</lei><title>Linde PLC</title><cusip>G54950103</cusip><identifiers><isin value="IE000S9YS762"/><ticker value="LIN US"/><other otherDesc="BNZHB81" value="Sedol"/></identifiers><balance>786164</balance><units>NS</units><curCd>USD</curCd><valUSD>292728165</valUSD><pctVal>1.768</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>ASML Holding NV</name><lei>724500Y6DUVHQD6OXN27</lei><title>ASML Holding NV</title><cusip>N07059210</cusip><identifiers><isin value="USN070592100"/><ticker value="ASML US"/><other otherDesc="B908F01" value="Sedol"/></identifiers><balance>510288</balance><units>NS</units><curCd>USD</curCd><valUSD>300386134</valUSD><pctVal>1.814</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Argenx SE</name><lei>7245009C5FZE6G9ODQ71</lei><title>Argenx SE (ADR)</title><cusip>04016X101</cusip><identifiers><isin value="US04016X1019"/><ticker value="ARGX US"/><other otherDesc="BDVLM39" value="Sedol"/></identifiers><balance>225963</balance><units>NS</units><curCd>USD</curCd><valUSD>111090190</valUSD><pctVal>0.671</pctVal><payoffProfile>Long</payoffProfile><assetConditional assetCat="OTHER" desc="GDR"/><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec></invstOrSecs><explntrNotes><explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/></explntrNotes><signature><ncom:dateSigned>2023-11-14</ncom:dateSigned><ncom:nameOfApplicant>JANUS INVESTMENT FUND</ncom:nameOfApplicant><ncom:signature>JESPER NERGAARD</ncom:signature><ncom:signerName>JESPER NERGAARD</ncom:signerName><ncom:title>VP, CFO, TREASURER, AND PRINCIPAL ACCOUNTING OFFICER</ncom:title></signature></formData></edgarSubmission>
