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value="Sedol"/></identifiers><balance>6149386</balance><units>NS</units><curCd>USD</curCd><valUSD>423385226</valUSD><pctVal>2.693</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Danaher Corp</name><lei>S4BKK9OTCEWQ3YHPFM11</lei><title>Danaher Corp</title><cusip>235851102</cusip><identifiers><isin value="US2358511028"/><ticker value="DHR US"/><other otherDesc="2250870" value="Sedol"/></identifiers><balance>1222533</balance><units>NS</units><curCd>USD</curCd><valUSD>308127217</valUSD><pctVal>1.96</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Deere &amp; Co</name><lei>PWFTNG3EI0Y73OXWDH08</lei><title>Deere &amp; Co</title><cusip>244199105</cusip><identifiers><isin value="US2441991054"/><ticker value="DE US"/><other otherDesc="2261203" value="Sedol"/></identifiers><balance>1239451</balance><units>NS</units><curCd>USD</curCd><valUSD>511744529</valUSD><pctVal>3.255</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Meta Platforms Inc</name><lei>BQ4BKCS1HXDV9HN80Z93</lei><title>Meta Platforms Inc - Class A</title><cusip>30303M102</cusip><identifiers><isin value="US30303M1027"/><ticker value="META US"/><other otherDesc="B7TL820" value="Sedol"/></identifiers><balance>1463378</balance><units>NS</units><curCd>USD</curCd><valUSD>310148333</valUSD><pctVal>1.972</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Freeport-McMoRan Inc</name><lei>549300IRDTHJQ1PVET45</lei><title>FREEPORT-MCMORAN INC</title><cusip>35671D857</cusip><identifiers><isin value="US35671D8570"/><ticker value="FCX US"/><other otherDesc="2352118" value="Sedol"/></identifiers><balance>4296175</balance><units>NS</units><curCd>USD</curCd><valUSD>175756519</valUSD><pctVal>1.118</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>LVMH Moet Hennessy Louis Vuitt</name><lei>IOG4E947OATN0KJYSD45</lei><title>LVMH Moet Hennessy Louis Vuitton SE</title><cusip>F58485115</cusip><identifiers><isin value="FR0000121014"/><ticker value="MC FP"/><other otherDesc="4061412" value="Sedol"/></identifiers><balance>370226</balance><units>NS</units><currencyConditional curCd="EUR" exchangeRt="0.92217"/><valUSD>339264847</valUSD><pctVal>2.158</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>FR</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Howmet Aerospace Inc</name><lei>549300HO5WFZUT5N2T22</lei><title>Howmet Aerospace Inc</title><cusip>443201108</cusip><identifiers><isin value="US4432011082"/><ticker value="HWM US"/><other otherDesc="BKLJ8V2" value="Sedol"/></identifiers><balance>6221261</balance><units>NS</units><curCd>USD</curCd><valUSD>263594829</valUSD><pctVal>1.676</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Illumina Inc</name><lei>SQ95QG8SR5Q56LSNF682</lei><title>ILLUMINA INC</title><cusip>452327109</cusip><identifiers><isin value="US4523271090"/><ticker value="ILMN US"/><other otherDesc="2613990" value="Sedol"/></identifiers><balance>1220900</balance><units>NS</units><curCd>USD</curCd><valUSD>283920295</valUSD><pctVal>1.806</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>JPMorgan Chase &amp; Co</name><lei>8I5DZWZKVSZI1NUHU748</lei><title>JPMorgan Chase &amp; Co</title><cusip>46625H100</cusip><identifiers><isin value="US46625H1005"/><ticker value="JPM US"/><other otherDesc="2190385" value="Sedol"/></identifiers><balance>1870525</balance><units>NS</units><curCd>USD</curCd><valUSD>243748113</valUSD><pctVal>1.55</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Marvell Technology Inc</name><lei>N/A</lei><title>Marvell Technology Inc</title><cusip>573874104</cusip><identifiers><isin value="US5738741041"/><ticker value="MRVL US"/><other otherDesc="BNKJSM5" value="Sedol"/></identifiers><balance>3556413</balance><units>NS</units><curCd>USD</curCd><valUSD>153992683</valUSD><pctVal>0.979</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Mastercard Inc</name><lei>AR5L2ODV9HN37376R084</lei><title>Mastercard Inc</title><cusip>57636Q104</cusip><identifiers><isin value="US57636Q1040"/><ticker value="MA US"/><other otherDesc="B121557" value="Sedol"/></identifiers><balance>2697269</balance><units>NS</units><curCd>USD</curCd><valUSD>980214527</valUSD><pctVal>6.234</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Microsoft Corp</name><lei>INR2EJN1ERAN0W5ZP974</lei><title>MICROSOFT CORP</title><cusip>594918104</cusip><identifiers><isin value="US5949181045"/><ticker value="MSFT US"/><other otherDesc="2588173" value="Sedol"/></identifiers><balance>6432481</balance><units>NS</units><curCd>USD</curCd><valUSD>1854484272</valUSD><pctVal>11.794</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>NIKE Inc</name><lei>787RXPR0UX0O0XUXPZ81</lei><title>NIKE Inc - Class B</title><cusip>654106103</cusip><identifiers><isin value="US6541061031"/><ticker value="NKE US"/><other otherDesc="2640147" value="Sedol"/></identifiers><balance>1579209</balance><units>NS</units><curCd>USD</curCd><valUSD>193674192</valUSD><pctVal>1.232</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>NVIDIA Corp</name><lei>549300S4KLFTLO7GSQ80</lei><title>NVIDIA Corp</title><cusip>67066G104</cusip><identifiers><isin value="US67066G1040"/><ticker value="NVDA US"/><other otherDesc="2379504" value="Sedol"/></identifiers><balance>1877208</balance><units>NS</units><curCd>USD</curCd><valUSD>521432066</valUSD><pctVal>3.316</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Procter &amp; Gamble Co/The</name><lei>2572IBTT8CCZW6AU4141</lei><title>Procter &amp; Gamble Co</title><cusip>742718109</cusip><identifiers><isin value="US7427181091"/><ticker value="PG US"/><other otherDesc="2704407" value="Sedol"/></identifiers><balance>1184856</balance><units>NS</units><curCd>USD</curCd><valUSD>176176239</valUSD><pctVal>1.12</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Rivian Automotive Inc</name><lei>N/A</lei><title>Rivian Automotive Inc - Class A</title><cusip>76954A103</cusip><identifiers><isin value="US76954A1034"/><ticker value="RIVN US"/><other otherDesc="BL98841" value="Sedol"/></identifiers><balance>2941451</balance><units>NS</units><curCd>USD</curCd><valUSD>45533662</valUSD><pctVal>0.29</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Charles Schwab Corp/The</name><lei>549300VSGCJ7E698NM85</lei><title>Charles Schwab Corp</title><cusip>808513105</cusip><identifiers><isin value="US8085131055"/><ticker value="SCHW US"/><other otherDesc="2779397" value="Sedol"/></identifiers><balance>2612285</balance><units>NS</units><curCd>USD</curCd><valUSD>136831488</valUSD><pctVal>0.87</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Sherwin-Williams Co/The</name><lei>Z15BMIOX8DDH0X2OBP21</lei><title>Sherwin-Williams Co</title><cusip>824348106</cusip><identifiers><isin value="US8243481061"/><ticker value="SHW US"/><other otherDesc="2804211" value="Sedol"/></identifiers><balance>725720</balance><units>NS</units><curCd>USD</curCd><valUSD>163120084</valUSD><pctVal>1.037</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>TJX Cos Inc/The</name><lei>V167QI9I69W364E2DY52</lei><title>TJX Cos Inc</title><cusip>872540109</cusip><identifiers><isin value="US8725401090"/><ticker value="TJX US"/><other otherDesc="2989301" value="Sedol"/></identifiers><balance>4519495</balance><units>NS</units><curCd>USD</curCd><valUSD>354147628</valUSD><pctVal>2.252</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Texas Instruments Inc</name><lei>WDJNR2L6D8RWOEB8T652</lei><title>TEXAS INSTRUMENTS INC</title><cusip>882508104</cusip><identifiers><isin value="US8825081040"/><ticker value="TXN US"/><other otherDesc="2885409" value="Sedol"/></identifiers><balance>2032535</balance><units>NS</units><curCd>USD</curCd><valUSD>378071835</valUSD><pctVal>2.404</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Janus Capital Group Inc</name><lei>8T2ZO87FU1KVPZIG9I59</lei><title>Janus Henderson Cash Liquidity Fund</title><cusip>N/A</cusip><identifiers><isin value="DU0000100962"/></identifiers><balance>504324791</balance><units>NS</units><curCd>USD</curCd><valUSD>504425656</valUSD><pctVal>3.208</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>PF</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>UnitedHealth Group Inc</name><lei>549300GHBMY8T5GXDE41</lei><title>UnitedHealth Group Inc</title><cusip>91324P102</cusip><identifiers><isin value="US91324P1021"/><ticker value="UNH US"/><other otherDesc="2917766" value="Sedol"/></identifiers><balance>899108</balance><units>NS</units><curCd>USD</curCd><valUSD>424909450</valUSD><pctVal>2.702</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Workday Inc</name><lei>549300J0DYC0N31V7G13</lei><title>Workday Inc</title><cusip>98138H101</cusip><identifiers><isin value="US98138H1014"/><ticker value="WDAY US"/><other otherDesc="B8K6ZD1" value="Sedol"/></identifiers><balance>3541464</balance><units>NS</units><curCd>USD</curCd><valUSD>731453975</valUSD><pctVal>4.652</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Linde PLC</name><lei>5299003QR1WT0EF88V51</lei><title>Linde PLC</title><cusip>G54950103</cusip><identifiers><isin value="IE000S9YS762"/><ticker value="LIN"/><other otherDesc="BNZHB81" value="Sedol"/></identifiers><balance>786164</balance><units>NS</units><curCd>USD</curCd><valUSD>279434132</valUSD><pctVal>1.777</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>IE</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>ASML Holding NV</name><lei>724500Y6DUVHQD6OXN27</lei><title>ASML Holding NV</title><cusip>N07059210</cusip><identifiers><isin value="USN070592100"/><ticker value="ASML US"/><other otherDesc="B908F01" value="Sedol"/></identifiers><balance>658154</balance><units>NS</units><curCd>USD</curCd><valUSD>448012009</valUSD><pctVal>2.849</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Argenx SE</name><lei>7245009C5FZE6G9ODQ71</lei><title>Argenx SE (ADR)</title><cusip>04016X101</cusip><identifiers><isin value="US04016X1019"/><ticker value="ARGX US"/><other otherDesc="BDVLM39" value="Sedol"/></identifiers><balance>225963</balance><units>NS</units><curCd>USD</curCd><valUSD>84189295</valUSD><pctVal>0.535</pctVal><payoffProfile>Long</payoffProfile><assetConditional assetCat="OTHER" desc="GDR"/><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec></invstOrSecs><explntrNotes><explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/></explntrNotes><signature><ncom:dateSigned>2023-05-15</ncom:dateSigned><ncom:nameOfApplicant>JANUS INVESTMENT FUND</ncom:nameOfApplicant><ncom:signature>JESPER NERGAARD</ncom:signature><ncom:signerName>JESPER NERGAARD</ncom:signerName><ncom:title>VP, CFO, TREASURER, AND PRINCIPAL ACCOUNTING OFFICER</ncom:title></signature></formData></edgarSubmission>
