NPORT-Pfalse0000277751XXXXXXXXS000010474C000028933C000077678C000077679C000077680C000077681C000077682C000083520C000114874JANUS INVESTMENT FUND811-018790000277751W6UYDZFUOFJ4HQQ32382151 DETROIT STREETDENVER802063033333863Janus Henderson Global Select FundS000010474YTNSNBKH822ME5K537982022-09-302021-12-31N2567530734289208125646386530000000000000505NAbbVie IncFR5LCKFTG8054YNNRU85AbbVie Inc00287Y109185066NSUSD250579360.977LongECCORPUSN1NNNAdobe IncFU4LY2G4933NH2E1CP29ADOBE INC00724F10141261NSUSD233974630.912LongECCORPUSN1NNNAir Products and Chemicals Inc7QEON6Y1RL5XR3R1W237Air Products & Chemicals Inc009158106127920NSUSD389209391.518LongECCORPUSN1NNNAlphabet Inc5493006MHB84DD0ZWV18Alphabet Inc - Class A02079K30519532NSUSD565849852.206LongECCORPUSN1NNNAmazon.com IncZXTILKJKG63JELOEG630Amazon.com Inc02313510611019NSUSD367410921.433LongECCORPUSN1NNNPrudential PLC5493001Z3ZE83NGK8Y12Prudential PLCG728991001451864NS250416230.976LongECCORPGBN1NNNAstraZeneca PLCPY6ZZQWO2IZFZC3IOL08AstraZeneca PLCG0593M107658512NS773357033.015LongECCORPGBN1NNNCaesars Entertainment Inc549300FA4CTCW903Y781Caesars Entertainment Inc12769G100633486NSUSD592499462.31LongECCORPUSN1NNNCanadian Natural Resources Ltd549300T15RIMIKZC5Q38Canadian Natural Resources Ltd1363851011396923NSUSD590199972.301LongECCORPUSN1NNNCitigroup Inc6SHGI4ZSSLCXXQSBB395Citigroup Inc1729674241349218NSUSD814792753.177LongECCORPUSN1NNNCrown Holdings IncNYLWZIOY8PUNIT4JOE22Crown Holdings Inc228368106478386NSUSD529190592.063LongECCORPUSN1NNNTeck Resources LtdT8KI5SQ2JRWHL7XY0E11Teck Resources Ltd8787422043268517NS941430063.671LongECCORPCAN1NNNAirbus SEMINO79WLOO247M1IL051Airbus SEN0280G100370357NS473723721.847LongECCORPFRN1NNNHumana Inc529900YLDW34GJAO4J06HUMANA INC44485910294314NSUSD437484921.706LongECCORPUSN1NNNL3Harris Technologies Inc549300UTE50ZMDBG8A20L3Harris Technologies Inc502431109165098NSUSD352054981.373LongECCORPUSN1NNNLiberty Media Corp-Liberty For549300ZKUTPIBZLWLL89Liberty Media Corp-Liberty Formula One531229854810667NSUSD512665811.999LongECCORPUSN1NNNMGIC Investment Corp254900S8483WM4M98R28MGIC Investment Corp5528481034596931NSUSD662877452.585LongECCORPUSN1NNNMarathon Petroleum Corp3BNYRYQHD39K4LCKQF12Marathon Petroleum Corp56585A102925733NSUSD592376552.31LongECCORPUSN1NNNMerck & Co Inc4YV9Y5M8S0BRK1RP0397Merck & Co Inc58933Y105262382NSUSD201089570.784LongECCORPUSN1NNNMicrosoft CorpINR2EJN1ERAN0W5ZP974MICROSOFT CORP594918104410615NSUSD1380980375.385LongECCORPUSN1NNNMonster Beverage Corp52990090AP0E7HCB6F33Monster Beverage Corp61174X109471753NSUSD453071581.767LongECCORPUSN1NNNMorgan StanleyIGJSJL3JD5P30I6NJZ34Morgan Stanley617446448908216NSUSD891504833.476LongECCORPUSN1NNNCentral Japan Railway Co353800YAR3OVUITHTG64Central Japan Railway CoJ05523105290300NS387327491.51LongECCORPJPN1NNNNRG Energy Inc5E2UPK5SW04M13XY7I38NRG Energy Inc6293775083151987NSUSD1357876005.295LongECCORPUSN1NNNNeurocrine Biosciences Inc549300FECER0XBN49756Neurocrine Biosciences Inc64125C109271920NSUSD231594260.903LongECCORPUSN1NNNNAVER Corp988400ULUQYDB2HQYJ61NAVER CorpY6257910070134NS223336020.871LongECCORPKRN1NNNNintendo Co Ltd353800FEEXU6I9M0ZF27NINTENDO CO LTDJ5169910653100NS247701500.966LongECCORPJPN1NNNSamsung Electronics Co Ltd9884007ER46L6N7EI764Samsung Electronics Co LtdY74718100450372NS296686251.157LongECCORPKRN1NNNOrganon & Co549300AMCKY57OK2CO56Organon & Co COMMON STOCK68622V1061757641NSUSD535201682.087LongECCORPUSN1NNNTSMC549300KB6NK5SBD14S87Taiwan Semiconductor Manufacturing Co LtdY846291073116000NS692895112.702LongECCORPTWN1NNNPulteGroup IncN/APulteGroup Inc7458671011191015NSUSD680784172.655LongECCORPUSN1NNNHeineken NV724500K5PTPSST86UQ23Heineken NVN39427211383135NS431186621.681LongECCORPNLN1NNNTJX Cos Inc/TheV167QI9I69W364E2DY52TJX Cos Inc872540109255844NSUSD194236760.757LongECCORPUSN1NNNT-Mobile US Inc549300QHIJYOHPACPG31T-MOBILE US INC872590104260036NSUSD301589751.176LongECCORPUSN1NNNTravelers Cos Inc/The549300Y650407RU8B149Travelers Cos Inc89417E109340569NSUSD532752092.077LongECCORPUSN1NNNJanus Capital Group Inc8T2ZO87FU1KVPZIG9I59Janus Henderson Cash Liquidity FundN/A10458543NSUSD104595890.408LongECPFUSN2NNNUnder Armour Inc549300D4549QKWETZ406Under Armour Inc9043112065012118NSUSD904186093.526LongECCORPUSN1NNNUnited Parcel Service IncD01LMJZU09ULLNCY6Z23United Parcel Service Inc911312106394038NSUSD844581053.293LongECCORPUSN1NNNWestinghouse Air Brake Technol06BTX5UWZD0GQ5N5Y745WABTEC CORP929740108433069NSUSD398899861.555LongECCORPUSN1NNNWorkday Inc549300J0DYC0N31V7G13Workday Inc98138H10175749NSUSD206931120.807LongECCORPUSN1NNNZendesk Inc549300SLI6BN94BKKO36ZENDESK INC98936J101119116NSUSD124226080.484LongECCORPUSN1NNNChina Construction Bank Corp5493001KQW6DM7KEDR62China Construction Bank CorpY1397N10150696000NS351093841.369LongECCORPHKN1NNNPrudential PLC5493001Z3ZE83NGK8Y12Prudential PLCG72899100206350NS35171040.137LongECCORPHKN1NNNSamsonite International SA549300UULS5HYFJSEL12Samsonite International SAL8030810615071400NS306171341.194LongECCORPHKY1NNNAIA Group LtdZP5ILWVSYE4LJGMMVD57AIA GROUP LTDY002A11051860000NS187495670.731LongECCORPHKN1NNNEntain PLC213800GNI3K45LQR8L28GVC Holdings PLCG427A61032408997NS548677412.139LongECCORPGBN1NNNASML Holding NV724500Y6DUVHQD6OXN27ASML HOLDING NVN0705920256456NS454190491.771LongECCORPNLN1NNNFerguson PLC213800DU1LGY3R2S2X42Ferguson PLCG3421J106418629NS742442862.895LongECCORPGBN1NNNAlibaba Group Holding Ltd5493001NTNQJDH60PM02Alibaba Group Holding LtdG017191141889884NS288185921.124LongECCORPHKN1NNNTencent Holdings Ltd254900N4SLUMW4XUYY11TENCENT HOLDINGS LTDG87572163644200NS377400591.472LongECCORPHKN1NNNNN Group NV724500OHYNDT9OY6Q215NN Group NVN64038107617536NS334698141.305LongECCORPNLN1NNNHexagon AB549300WJFW6ILNI4TA80Hexagon AB - Class BW4R4311123179421NS505616991.971LongECCORPSEN1NNNPermanent TSB Group Holdings P635400DTNHVYGZODKQ93Permanent TSB Group Holdings PLCG7015D1105262077NS95845120.374LongECCORPIEN1NNNBeazley PLC213800VTOMUWD41GIT12Beazley PLCG0936K1073483289NS219812120.857LongECCORPGBN1NNNN/AN/AMagic Leap Inc PP - Class AN/A19041NSUSD00LongEPCORPUSY3NNNAscendis Pharma A/S549300B66JN3W3J8GH73Ascendis Pharma A/S (ADR)04351P10188178NSUSD118625860.463LongCORPUSN1NNNSea Ltd529900OM6JLLW44YKI15Sea Ltd (ADR)81141R10056822NSUSD127116500.496LongCORPUSN1NNN2022-02-14JANUS INVESTMENT FUNDJESPER NERGAARDJESPER NERGAARDVP, CFO, TREASURER, AND PRINCIPAL ACCOUNTING OFFICERXXXX