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value="Sedol"/></identifiers><balance>3870535</balance><units>NS</units><curCd>USD</curCd><valUSD>145067652</valUSD><pctVal>0.67</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Altimeter Growth Corp</name><lei>N/A</lei><title>Altimeter Growth Corp</title><cusip>N/A</cusip><identifiers><isin value="DU0000104269"/></identifiers><balance>10072446</balance><units>NS</units><curCd>USD</curCd><valUSD>102940398</valUSD><pctVal>0.476</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>Y</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Freeport-McMoRan Inc</name><lei>549300IRDTHJQ1PVET45</lei><title>FREEPORT-MCMORAN INC</title><cusip>35671D857</cusip><identifiers><isin value="US35671D8570"/><ticker value="FCX US"/><other otherDesc="2352118" value="Sedol"/></identifiers><balance>4441763</balance><units>NS</units><curCd>USD</curCd><valUSD>144490550</valUSD><pctVal>0.668</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>LVMH Moet Hennessy Louis Vuitt</name><lei>IOG4E947OATN0KJYSD45</lei><title>LVMH Moet Hennessy Louis Vuitton SE</title><cusip>F58485115</cusip><identifiers><isin value="FR0000121014"/><ticker value="MC FP"/><other otherDesc="4061412" value="Sedol"/></identifiers><balance>524661</balance><units>NS</units><currencyConditional curCd="EUR" 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value="Sedol"/></identifiers><balance>1667736</balance><units>NS</units><curCd>USD</curCd><valUSD>367302177</valUSD><pctVal>1.698</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Mastercard Inc</name><lei>AR5L2ODV9HN37376R084</lei><title>Mastercard Inc</title><cusip>57636Q104</cusip><identifiers><isin value="US57636Q1040"/><ticker value="MA US"/><other otherDesc="B121557" value="Sedol"/></identifiers><balance>3176781</balance><units>NS</units><curCd>USD</curCd><valUSD>1104503218</valUSD><pctVal>5.105</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Match Group Inc</name><lei>15OMOPB0A8K0EFUVD031</lei><title>Match Group Inc</title><cusip>57667L107</cusip><identifiers><isin value="US57667L1070"/><ticker value="MTCH US"/><other otherDesc="BK80XH9" value="Sedol"/></identifiers><balance>2151094</balance><units>NS</units><curCd>USD</curCd><valUSD>337700247</valUSD><pctVal>1.561</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Microsoft Corp</name><lei>INR2EJN1ERAN0W5ZP974</lei><title>MICROSOFT CORP</title><cusip>594918104</cusip><identifiers><isin value="US5949181045"/><ticker value="MSFT US"/><other otherDesc="2588173" value="Sedol"/></identifiers><balance>6432481</balance><units>NS</units><curCd>USD</curCd><valUSD>1813445044</valUSD><pctVal>8.381</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Netflix Inc</name><lei>549300Y7VHGU0I7CE873</lei><title>Netflix Inc</title><cusip>64110L106</cusip><identifiers><isin value="US64110L1061"/><ticker value="NFLX US"/><other otherDesc="2857817" value="Sedol"/></identifiers><balance>862215</balance><units>NS</units><curCd>USD</curCd><valUSD>526244303</valUSD><pctVal>2.432</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>NIKE Inc</name><lei>787RXPR0UX0O0XUXPZ81</lei><title>NIKE Inc - Class B</title><cusip>654106103</cusip><identifiers><isin value="US6541061031"/><ticker value="NKE US"/><other otherDesc="2640147" value="Sedol"/></identifiers><balance>1866804</balance><units>NS</units><curCd>USD</curCd><valUSD>271115945</valUSD><pctVal>1.253</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>NVIDIA Corp</name><lei>549300S4KLFTLO7GSQ80</lei><title>NVIDIA CORP</title><cusip>67066G104</cusip><identifiers><isin value="US67066G1040"/><ticker value="NVDA US"/><other otherDesc="2379504" value="Sedol"/></identifiers><balance>3568072</balance><units>NS</units><curCd>USD</curCd><valUSD>739161796</valUSD><pctVal>3.416</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Procter &amp; Gamble Co/The</name><lei>2572IBTT8CCZW6AU4141</lei><title>Procter &amp; Gamble Co</title><cusip>742718109</cusip><identifiers><isin value="US7427181091"/><ticker value="PG US"/><other otherDesc="2704407" value="Sedol"/></identifiers><balance>2762335</balance><units>NS</units><curCd>USD</curCd><valUSD>386174433</valUSD><pctVal>1.785</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Sherwin-Williams Co/The</name><lei>Z15BMIOX8DDH0X2OBP21</lei><title>Sherwin-Williams Co</title><cusip>824348106</cusip><identifiers><isin value="US8243481061"/><ticker value="SHW US"/><other otherDesc="2804211" value="Sedol"/></identifiers><balance>1690251</balance><units>NS</units><curCd>USD</curCd><valUSD>472813912</valUSD><pctVal>2.185</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Shopify Inc</name><lei>549300HGQ43STJLLP808</lei><title>Shopify Inc</title><cusip>82509L107</cusip><identifiers><isin value="CA82509L1076"/><ticker value="SHOP CN"/><other otherDesc="BXDZ9Z0" 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value="Sedol"/></identifiers><balance>10782027</balance><units>NS</units><curCd>USD</curCd><valUSD>796468334</valUSD><pctVal>3.681</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>T-Mobile US Inc</name><lei>549300QHIJYOHPACPG31</lei><title>T-MOBILE US INC</title><cusip>872590104</cusip><identifiers><isin value="US8725901040"/><ticker value="TMUS US"/><other otherDesc="B94Q9V0" 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value="DU0000100962"/></identifiers><balance>491081383</balance><units>NS</units><curCd>USD</curCd><valUSD>491130492</valUSD><pctVal>2.27</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>PF</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Janus Henderson Cash Collateral Fund</name><lei>N/A</lei><title>Janus Henderson Cash Collateral Fund</title><cusip>N/A</cusip><identifiers><other otherDesc="896" value="Internal ID"/></identifiers><balance>30214439</balance><units>NS</units><curCd>USD</curCd><valUSD>30214439</valUSD><pctVal>0.14</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>PF</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><cashCollateralCondition cashCollateralVal="30214439" isCashCollateral="Y"/><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Twilio Inc</name><lei>5493004W8TRGD63APX93</lei><title>Twilio Inc</title><cusip>90138F102</cusip><identifiers><isin value="US90138F1021"/><ticker value="TWLO US"/><other otherDesc="BD6P5Q0" value="Sedol"/></identifiers><balance>1148203</balance><units>NS</units><curCd>USD</curCd><valUSD>366334167</valUSD><pctVal>1.693</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Unity Software Inc</name><lei>N/A</lei><title>Unity Software Inc</title><cusip>91332U101</cusip><identifiers><isin value="US91332U1016"/><ticker value="U US"/><other otherDesc="BLFDXH8" value="Sedol"/></identifiers><balance>1236185</balance><units>NS</units><curCd>USD</curCd><valUSD>156068356</valUSD><pctVal>0.721</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Workday Inc</name><lei>549300J0DYC0N31V7G13</lei><title>Workday Inc</title><cusip>98138H101</cusip><identifiers><isin value="US98138H1014"/><ticker value="WDAY US"/><other otherDesc="B8K6ZD1" value="Sedol"/></identifiers><balance>1160073</balance><units>NS</units><curCd>USD</curCd><valUSD>289890642</valUSD><pctVal>1.34</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Altimeter Growth Corp</name><lei>N/A</lei><title>Altimeter Growth Corp - Class A</title><cusip>G0370L108</cusip><identifiers><isin value="KYG0370L1086"/><ticker value="AGC US"/><other otherDesc="BMGWR02" value="Sedol"/></identifiers><balance>4920075</balance><units>NS</units><curCd>USD</curCd><valUSD>50283167</valUSD><pctVal>0.232</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><loanByFundCondition isLoanByFund="Y" loanVal="36826219.98"/></securityLending></invstOrSec><invstOrSec><name>ASML Holding NV</name><lei>724500Y6DUVHQD6OXN27</lei><title>ASML Holding NV</title><cusip>N07059210</cusip><identifiers><isin value="USN070592100"/><ticker value="ASML US"/><other otherDesc="B908F01" value="Sedol"/></identifiers><balance>885683</balance><units>NS</units><curCd>USD</curCd><valUSD>659931260</valUSD><pctVal>3.05</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>TSMC</name><lei>549300KB6NK5SBD14S87</lei><title>Taiwan Semiconductor Manufacturing Co Ltd (ADR)</title><cusip>874039100</cusip><identifiers><isin value="US8740391003"/><ticker value="TSM US"/><other otherDesc="2113382" value="Sedol"/></identifiers><balance>2818336</balance><units>NS</units><curCd>USD</curCd><valUSD>314667214</valUSD><pctVal>1.454</pctVal><payoffProfile>Long</payoffProfile><assetConditional assetCat="OTHER" desc="GDR"/><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>N/A</name><lei>N/A</lei><title>Altimeter Growth Corp</title><cusip>N/A</cusip><identifiers><isin value="KYG0370L1169"/><ticker value="AGCWW"/><other otherDesc="G0370L116" value="Internal ID"/></identifiers><balance>984015</balance><units>NS</units><curCd>USD</curCd><valUSD>2174673</valUSD><pctVal>0.01</pctVal><payoffProfile>N/A</payoffProfile><assetCat>DE</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><derivativeInfo><optionSwaptionWarrantDeriv derivCat="WAR"><counterparties><counterpartyName>N/A</counterpartyName><counterpartyLei>N/A</counterpartyLei></counterparties><putOrCall>Call</putOrCall><writtenOrPur>Purchased</writtenOrPur><descRefInstrmnt><otherRefInst><issuerName>Altimeter Growth Corp</issuerName><issueTitle>Altimeter Growth Corp</issueTitle><identifiers><cusip value="N/A"/><isin value="KYG0370L1086"/><ticker value="AGC US"/></identifiers></otherRefInst></descRefInstrmnt><shareNo>984015</shareNo><exercisePrice>11.5</exercisePrice><exercisePriceCurCd>USD</exercisePriceCurCd><expDt>2025-09-30</expDt><delta>XXXX</delta><unrealizedAppr>-970572</unrealizedAppr></optionSwaptionWarrantDeriv></derivativeInfo><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec></invstOrSecs><explntrNotes><explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/></explntrNotes><signature><ncom:dateSigned>2021-11-14</ncom:dateSigned><ncom:nameOfApplicant>JANUS INVESTMENT FUND</ncom:nameOfApplicant><ncom:signature>JESPER NERGAARD</ncom:signature><ncom:signerName>JESPER NERGAARD</ncom:signerName><ncom:title>VP, CFO, TREASURER, AND PRINCIPAL ACCOUNTING OFFICER</ncom:title></signature></formData></edgarSubmission>
