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value="Sedol"/></identifiers><balance>1660688</balance><units>NS</units><curCd>USD</curCd><valUSD>416018951</valUSD><pctVal>2.663</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Intuitive Surgical Inc</name><lei>54930052SRG011710797</lei><title>Intuitive Surgical Inc</title><cusip>46120E602</cusip><identifiers><isin value="US46120E6023"/><ticker value="ISRG US"/><other otherDesc="2871301" value="Sedol"/></identifiers><balance>482641</balance><units>NS</units><curCd>USD</curCd><valUSD>275023321</valUSD><pctVal>1.76</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>L3Harris Technologies Inc</name><lei>549300UTE50ZMDBG8A20</lei><title>L3Harris Technologies Inc</title><cusip>502431109</cusip><identifiers><isin value="US5024311095"/><ticker value="LHX US"/><other otherDesc="BK9DTN5" value="Sedol"/></identifiers><balance>1963046</balance><units>NS</units><curCd>USD</curCd><valUSD>333070015</valUSD><pctVal>2.132</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Lam Research Corp</name><lei>549300I4GMO6D34U1T02</lei><title>Lam Research Corp</title><cusip>512807108</cusip><identifiers><isin value="US5128071082"/><ticker value="LRCX US"/><other otherDesc="2502247" value="Sedol"/></identifiers><balance>483711</balance><units>NS</units><curCd>USD</curCd><valUSD>156461160</valUSD><pctVal>1.001</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Lululemon Athletica Inc</name><lei>549300D9GZ4BMLDW5T40</lei><title>Lululemon Athletica Inc</title><cusip>550021109</cusip><identifiers><isin value="US5500211090"/><ticker value="LULU US"/><other otherDesc="B23FN39" value="Sedol"/></identifiers><balance>377007</balance><units>NS</units><curCd>USD</curCd><valUSD>117629954</valUSD><pctVal>0.753</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Mastercard Inc</name><lei>AR5L2ODV9HN37376R084</lei><title>Mastercard Inc</title><cusip>57636Q104</cusip><identifiers><isin value="US57636Q1040"/><ticker value="MA US"/><other otherDesc="B121557" value="Sedol"/></identifiers><balance>3049224</balance><units>NS</units><curCd>USD</curCd><valUSD>901655537</valUSD><pctVal>5.771</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Match Group Inc/old</name><lei>549300BIJKT86CPCKK96</lei><title>Match Group Inc</title><cusip>57665R106</cusip><identifiers><isin value="US57665R1068"/><ticker value="MTCH US"/><other otherDesc="BYT5JW8" value="Sedol"/></identifiers><balance>1699389</balance><units>NS</units><curCd>USD</curCd><valUSD>181919593</valUSD><pctVal>1.164</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><loanByFundCondition isLoanByFund="Y" loanVal="170229216"/></securityLending></invstOrSec><invstOrSec><name>Merck &amp; Co Inc</name><lei>4YV9Y5M8S0BRK1RP0397</lei><title>Merck &amp; Co Inc</title><cusip>58933Y105</cusip><identifiers><isin value="US58933Y1055"/><ticker value="MRK US"/><other otherDesc="2778844" value="Sedol"/></identifiers><balance>3306019</balance><units>NS</units><curCd>USD</curCd><valUSD>255654449</valUSD><pctVal>1.636</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Microsoft Corp</name><lei>INR2EJN1ERAN0W5ZP974</lei><title>Microsoft Corp</title><cusip>594918104</cusip><identifiers><isin value="US5949181045"/><ticker value="MSFT US"/><other otherDesc="2588173" value="Sedol"/></identifiers><balance>6666744</balance><units>NS</units><curCd>USD</curCd><valUSD>1356749071</valUSD><pctVal>8.684</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Microchip Technology Inc</name><lei>5493007PTFULNYZJ1R12</lei><title>Microchip Technology Inc</title><cusip>595017104</cusip><identifiers><isin value="US5950171042"/><ticker value="MCHP US"/><other otherDesc="2592174" value="Sedol"/></identifiers><balance>1252313</balance><units>NS</units><curCd>USD</curCd><valUSD>131881082</valUSD><pctVal>0.844</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Netflix Inc</name><lei>549300Y7VHGU0I7CE873</lei><title>Netflix Inc</title><cusip>64110L106</cusip><identifiers><isin value="US64110L1061"/><ticker value="NFLX US"/><other otherDesc="2857817" 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value="Sedol"/></identifiers><balance>2750573</balance><units>NS</units><curCd>USD</curCd><valUSD>349240254</valUSD><pctVal>2.235</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Janus Capital Group Inc</name><lei>8T2ZO87FU1KVPZIG9I59</lei><title>Janus Henderson Cash Liquidity Fund</title><cusip>N/A</cusip><identifiers><other otherDesc="895" value="Internal 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ID"/></identifiers><balance>139060260</balance><units>NS</units><curCd>USD</curCd><valUSD>139060260</valUSD><pctVal>0.89</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>PF</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>2</fairValLevel><securityLending><cashCollateralCondition cashCollateralVal="139060260" isCashCollateral="Y"/><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Vulcan Materials Co</name><lei>549300Q8LSNHAVWBNI21</lei><title>Vulcan Materials Co</title><cusip>929160109</cusip><identifiers><isin value="US9291601097"/><ticker value="VMC US"/><other otherDesc="2931205" value="Sedol"/></identifiers><balance>1121784</balance><units>NS</units><curCd>USD</curCd><valUSD>129958676</valUSD><pctVal>0.832</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>Zoetis Inc</name><lei>549300HD9Q1LOC9KLJ48</lei><title>Zoetis Inc</title><cusip>98978V103</cusip><identifiers><isin value="US98978V1035"/><ticker value="ZTS US"/><other otherDesc="B95WG16" value="Sedol"/></identifiers><balance>1772591</balance><units>NS</units><curCd>USD</curCd><valUSD>242915871</valUSD><pctVal>1.555</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>US</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec><invstOrSec><name>ASML Holding NV</name><lei>724500Y6DUVHQD6OXN27</lei><title>ASML Holding NV</title><cusip>N07059210</cusip><identifiers><isin value="USN070592100"/><ticker value="ASML US"/><other otherDesc="B908F01" value="Sedol"/></identifiers><balance>996673</balance><units>NS</units><curCd>USD</curCd><valUSD>366805564</valUSD><pctVal>2.348</pctVal><payoffProfile>Long</payoffProfile><assetCat>EC</assetCat><issuerCat>CORP</issuerCat><invCountry>NL</invCountry><isRestrictedSec>N</isRestrictedSec><fairValLevel>1</fairValLevel><securityLending><isCashCollateral>N</isCashCollateral><isNonCashCollateral>N</isNonCashCollateral><isLoanByFund>N</isLoanByFund></securityLending></invstOrSec></invstOrSecs><explntrNotes><explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/></explntrNotes><signature><ncom:dateSigned>2020-08-14</ncom:dateSigned><ncom:nameOfApplicant>JANUS INVESTMENT FUND</ncom:nameOfApplicant><ncom:signature>JESPER NERGAARD</ncom:signature><ncom:signerName>JESPER NERGAARD</ncom:signerName><ncom:title>VP, CFO, TREASURER, AND PRINCIPAL ACCOUNTING OFFICER</ncom:title></signature></nport:formData><nport:documents>XXXX</nport:documents></nport:edgarSubmission>
