Exhibit (g)(24)

LETTER AGREEMENT

August 26, 2010

Mr. Matthew Kelly
State Street Bank and Trust Company
Global Investor Services Group
2 Avenue de Lafayette LCC2S
Boston, Massachusetts 02111

Dear Mr. Kelly:

This letter is to notify you that Janus Investment Fund (the “Trust”) will change the name of Janus Orion Fund to Janus Global Select Fund (the “Fund”), effective September 15, 2010. The Trust requests confirmation that all references to “Janus Orion Fund” in the Amended and Restated Custodian Contract dated August 1, 2005, as amended, between the Trust and State Street Bank and Trust Company (“State Street”) (the “Custodian Contract”), shall be replaced with “Janus Global Select Fund,” and that State Street will continue to act as custodian for the Fund under the terms of the Custodian Contract.

Please indicate your acceptance of the foregoing by executing two copies of this letter, returning one copy to the Trust and retaining one copy for your records.

JANUS INVESTMENT FUND
By:	/s/ Stephanie Grauerholz-Lofton Stephanie Grauerholz-Lofton
	Vice President and Secretary
STATE STREET BANK AND TRUST COMPANY
By:	/s/ Michael F. Rogers Michael F. Rogers
	Executive Vice President

Agreed to this 1st day of September, 2010.