<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0000277751</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000010475</seriesId>
        <classId>C000077683</classId>
        <classId>C000077684</classId>
        <classId>C000083521</classId>
        <classId>C000077685</classId>
        <classId>C000114875</classId>
        <classId>C000077686</classId>
        <classId>C000077687</classId>
        <classId>C000028934</classId>
      </seriesClassInfo>


    </filerInfo>
  </headerData>
  <formData>
    <genInfo>
      <regName>JANUS INVESTMENT FUND</regName>
      <regFileNumber>811-01879</regFileNumber>
      <regCik>0000277751</regCik>
      <regLei>W6UYDZFUOFJ4HQQ32382</regLei>
      <regStreet1>151 Detroit Street</regStreet1>
      <regCity>Denver</regCity>
      <regStateConditional regCountry="US" regState="US-CO"/>
      <regZipOrPostalCode>80206</regZipOrPostalCode>
      <regPhone>303-333-3863</regPhone>
      <seriesName>Janus Henderson Contrarian Fund</seriesName>
      <seriesId>S000010475</seriesId>
      <seriesLei>05B6OC1W7N8NJQRIYS63</seriesLei>
      <repPdEnd>2026-09-30</repPdEnd>
      <repPdDate>2026-03-31</repPdDate>
      <isFinalFiling>N</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>4304734660.280000000000</totAssets>
      <totLiabs>18507474.050000000000</totLiabs>
      <netAssets>4286227186.230000000000</netAssets>
      <assetsAttrMiscSec>0.000000000000</assetsAttrMiscSec>
      <assetsInvested>0.000000000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.000000000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.000000000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.000000000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.000000000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.000000000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.000000000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.000000000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.000000000000</amtPayAftOneYrOther>
      <delayDeliv>0.000000000000</delayDeliv>
      <standByCommit>0.000000000000</standByCommit>
      <liquidPref>0.000000000000</liquidPref>
      <cshNotRptdInCorD>15370000.000000000000</cshNotRptdInCorD>
      <borrowers>
        <borrower aggrVal="29426050.000000000000" lei="FOR8UP27PHTHYVLBNG30" name="GOLDMAN SACHS &amp; CO. LLC"/>
        <borrower aggrVal="11093066.000000000000" lei="VYVVCKR63DVZZN70PB21" name="WELLS FARGO SECURITIES, LLC"/>
        <borrower aggrVal="266160.000000000000" lei="AC28XWWI3WIBK2824319" name="BARCLAYS CAPITAL, INC."/>
        <borrower aggrVal="3490123.000000000000" lei="549300KUN9K9K32C6D97" name="BNP PARIBAS PRIME BROKERAGE INTERNATIONAL LIMITED"/>
        <borrower aggrVal="7529001.000000000000" lei="549300HN4UKV1E2R3U73" name="BOFA SECURITIES, INC."/>
        <borrower aggrVal="14686709.000000000000" lei="MBNUM2BPBDO7JBLYG310" name="Citigroup Global Markets Inc."/>
      </borrowers>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000028934" rtn1="-1.83" rtn2="2.40" rtn3="-5.42"/>
          <monthlyTotReturn classId="C000077683" rtn1="-1.80" rtn2="2.37" rtn3="-5.42"/>
          <monthlyTotReturn classId="C000077684" rtn1="-1.85" rtn2="2.29" rtn3="-5.49"/>
          <monthlyTotReturn classId="C000077685" rtn1="-1.79" rtn2="2.39" rtn3="-5.41"/>
          <monthlyTotReturn classId="C000077686" rtn1="-1.89" rtn2="2.38" rtn3="-5.49"/>
          <monthlyTotReturn classId="C000077687" rtn1="-1.85" rtn2="2.38" rtn3="-5.44"/>
          <monthlyTotReturn classId="C000083521" rtn1="-1.79" rtn2="2.39" rtn3="-5.41"/>
          <monthlyTotReturn classId="C000114875" rtn1="-1.79" rtn2="2.44" rtn3="-5.43"/>
        </monthlyTotReturns>
        <monthlyReturnCats>
          <equityContracts>
            <mon1 netRealizedGain="580000" netUnrealizedAppr="-4751440"/>
            <mon2 netRealizedGain="-12169000" netUnrealizedAppr="4722023"/>
            <mon3 netRealizedGain="2524500" netUnrealizedAppr="2110423"/>
            <optionCategory>
              <instrMon1 netRealizedGain="580000" netUnrealizedAppr="-4751440"/>
              <instrMon2 netRealizedGain="-12169000" netUnrealizedAppr="4722023"/>
              <instrMon3 netRealizedGain="2524500" netUnrealizedAppr="2110423"/>
            </optionCategory>
          </equityContracts>
        </monthlyReturnCats>
        <othMon1 netRealizedGain="-32126040" netUnrealizedAppr="-47239644"/>
        <othMon2 netRealizedGain="83680318" netUnrealizedAppr="29105504"/>
        <othMon3 netRealizedGain="-58629162" netUnrealizedAppr="-194881757"/>
      </returnInfo>
      <mon1Flow redemption="79215741.16" reinvestment="0.00" sales="26121136.11"/>
      <mon2Flow redemption="73067055.50" reinvestment="-32.99" sales="23625282.29"/>
      <mon3Flow redemption="89727982.32" reinvestment="-2468.32" sales="21156859.14"/>



      <varInfo>

        <fundsDesignatedInfo>
          <nameDesignatedIndex>S&amp;P 500</nameDesignatedIndex>
          <indexIdentifier>SP.MC.SPX</indexIdentifier>

        </fundsDesignatedInfo>

      </varInfo>
    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>Capital One Financial Corp.</name>
        <lei>ZUE8T73ROZOF6FLBAR73</lei>
        <title>Capital One Financial Corp. COM USD0.01</title>
        <cusip>14040H105</cusip>
        <identifiers>
          <isin value="US14040H1059"/>
          <ticker value="COF"/>
          <other otherDesc="SEDOL" value="2654461"/>
        </identifiers>
        <balance>1132978</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>206689176.54</valUSD>
        <pctVal>4.8221703507</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cipher Digital Inc.</name>
        <lei>254900QABG5HCQZ28A17</lei>
        <title>Cipher Digital Inc. COM</title>
        <cusip>17253J106</cusip>
        <identifiers>
          <isin value="US17253J1060"/>
          <ticker value="CIFR"/>
          <other otherDesc="SEDOL" value="BMZ8604"/>
        </identifiers>
        <balance>3990867</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>51362458.29</valUSD>
        <pctVal>1.1983139497</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Core &amp; Main Inc</name>
        <lei>N/A</lei>
        <title>Core &amp; Main Inc CL A</title>
        <cusip>21874C102</cusip>
        <identifiers>
          <isin value="US21874C1027"/>
          <ticker value="CNM"/>
          <other otherDesc="SEDOL" value="BNXKS92"/>
        </identifiers>
        <balance>1182716</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>58426170.4</valUSD>
        <pctVal>1.3631141762</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cullen/Frost Bankers, Inc.</name>
        <lei>529900V2E9G9AY665O34</lei>
        <title>Cullen/Frost Bankers, Inc. COM USD0.01</title>
        <cusip>229899109</cusip>
        <identifiers>
          <isin value="US2298991090"/>
          <ticker value="CFR"/>
          <other otherDesc="SEDOL" value="2239556"/>
        </identifiers>
        <balance>619839</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>84967530.12</valUSD>
        <pctVal>1.9823384629</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>OTCOption/CALL American Equity.VERTIV HOLDINGS CO_</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="CAXXDAC5"/>
        </identifiers>
        <balance>-2500</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-5137787.25</valUSD>
        <pctVal>-0.1198673572</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>Morgan Stanley &amp; Co. International PLC</counterpartyName>
              <counterpartyLei>4PQUHN3JPFGFNF3BB653</counterpartyLei>
            </counterparties>
            <putOrCall>Call</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>Vertiv Holdings Co</issuerName>
                <issueTitle>Vertiv Holdings Co</issueTitle>
                <identifiers>
                  <cusip value="92537N108"/>
                  <isin value="US92537N1081"/>
                  <ticker value="VRT"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100</shareNo>
            <exercisePrice>240.000000000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2026-04-17</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>462212.75</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Datadog Inc</name>
        <lei>549300F6JNO0KRPO1K63</lei>
        <title>Datadog Inc COM USD0.00001 CL A</title>
        <cusip>23804L103</cusip>
        <identifiers>
          <isin value="US23804L1035"/>
          <ticker value="DDOG"/>
          <other otherDesc="SEDOL" value="BKT9Y49"/>
        </identifiers>
        <balance>338572</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>39968424.6</valUSD>
        <pctVal>0.9324849772</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PFIZER INC</name>
        <lei>N/A</lei>
        <title>PFIZER INC-CVR</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="DU0US0005090"/>
          <ticker value="2596459D"/>
          <other otherDesc="Internal ID" value="3332853"/>
        </identifiers>
        <balance>309842</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1518225.8</valUSD>
        <pctVal>0.0354210296</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetConditional assetCat="OTHER" desc="Rights"/>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Forgent Power Solutions Inc.</name>
        <lei>N/A</lei>
        <title>Forgent Power Solutions Inc. COM SHS CL A</title>
        <cusip>34631F102</cusip>
        <identifiers>
          <isin value="US34631F1021"/>
          <ticker value="FPS"/>
          <other otherDesc="SEDOL" value="BV9C843"/>
        </identifiers>
        <balance>3355347</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>98211006.69</valUSD>
        <pctVal>2.2913159388</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Glaukos Corp.</name>
        <lei>5299004JA1LHE21M6T14</lei>
        <title>Glaukos Corp. COM USD0.001</title>
        <cusip>377322102</cusip>
        <identifiers>
          <isin value="US3773221029"/>
          <ticker value="GKOS"/>
          <other otherDesc="SEDOL" value="BYMWL19"/>
        </identifiers>
        <balance>639308</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>68827899.28</valUSD>
        <pctVal>1.6057921405</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Howmet Aerospace Inc</name>
        <lei>549300HO5WFZUT5N2T22</lei>
        <title>Howmet Aerospace Inc COM</title>
        <cusip>443201108</cusip>
        <identifiers>
          <isin value="US4432011082"/>
          <ticker value="HWM"/>
          <other otherDesc="SEDOL" value="BKLJ8V2"/>
        </identifiers>
        <balance>766246</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>176589053.16</valUSD>
        <pctVal>4.1199181818</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Intercontinental Exchange Inc</name>
        <lei>5493000F4ZO33MV32P92</lei>
        <title>Intercontinental Exchange Inc COM USD0.01</title>
        <cusip>45866F104</cusip>
        <identifiers>
          <isin value="US45866F1049"/>
          <ticker value="ICE"/>
          <other otherDesc="SEDOL" value="BFSSDS9"/>
        </identifiers>
        <balance>658321</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>103540726.88</valUSD>
        <pctVal>2.4156611953</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>OTCOption/PUT American Equity.UNITEDHEALTH GROUP_U</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="CAXXDA3E"/>
        </identifiers>
        <balance>-1000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-8941000</valUSD>
        <pctVal>-0.2085983690</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>Bank of America, National Association</counterpartyName>
              <counterpartyLei>B4TYDEB6GKMZO031MB27</counterpartyLei>
            </counterparties>
            <putOrCall>Put</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>UNITEDHEALTH GROUP INC</issuerName>
                <issueTitle>UNITEDHEALTH GROUP INC</issueTitle>
                <identifiers>
                  <cusip value="91324P102"/>
                  <isin value="US91324P1021"/>
                  <ticker value="UNH"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100</shareNo>
            <exercisePrice>360.000000000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2026-04-17</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>309000</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>OTCOption/PUT American Equity.AMAZON COM_US_USD_XN</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="CAXXDAFD"/>
        </identifiers>
        <balance>-1000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-948604.7</valUSD>
        <pctVal>-0.0221314610</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>Bank of America, National Association</counterpartyName>
              <counterpartyLei>B4TYDEB6GKMZO031MB27</counterpartyLei>
            </counterparties>
            <putOrCall>Put</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>AMAZON.COM INC</issuerName>
                <issueTitle>AMAZON.COM INC</issueTitle>
                <identifiers>
                  <cusip value="023135106"/>
                  <isin value="US0231351067"/>
                  <ticker value="AMZN"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100</shareNo>
            <exercisePrice>215.000000000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2026-04-17</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>386395.3</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Legence Corp.</name>
        <lei>N/A</lei>
        <title>Legence Corp. CL A</title>
        <cusip>52476L109</cusip>
        <identifiers>
          <isin value="US52476L1098"/>
          <ticker value="LGN"/>
          <other otherDesc="SEDOL" value="BT6CC17"/>
        </identifiers>
        <balance>1054758</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>59551636.68</valUSD>
        <pctVal>1.3893719136</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Lumentum Holdings Inc.</name>
        <lei>549300JLWRRC38DWEF52</lei>
        <title>Lumentum Holdings Inc. COM USD0.001</title>
        <cusip>55024U109</cusip>
        <identifiers>
          <isin value="US55024U1097"/>
          <ticker value="LITE"/>
          <other otherDesc="SEDOL" value="BYM9ZP2"/>
        </identifiers>
        <balance>228439</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>160537791.64</valUSD>
        <pctVal>3.7454335635</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>OTCOption/PUT American Equity.ORACLE_US_USD_XASE 1</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="CAXXDAZD"/>
        </identifiers>
        <balance>-1000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-573611.1</valUSD>
        <pctVal>-0.0133826574</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>Bank of America, National Association</counterpartyName>
              <counterpartyLei>B4TYDEB6GKMZO031MB27</counterpartyLei>
            </counterparties>
            <putOrCall>Put</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>ORACLE CORP</issuerName>
                <issueTitle>ORACLE CORP</issueTitle>
                <identifiers>
                  <cusip value="68389X105"/>
                  <isin value="US68389X1054"/>
                  <ticker value="ORCL"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100</shareNo>
            <exercisePrice>145.000000000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2026-04-17</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>-70611.1</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Madrigal Pharmaceuticals Inc</name>
        <lei>549300CHIMT2EUSNJB60</lei>
        <title>Madrigal Pharmaceuticals Inc USD0.0001</title>
        <cusip>558868105</cusip>
        <identifiers>
          <isin value="US5588681057"/>
          <ticker value="MDGL"/>
          <other otherDesc="SEDOL" value="BD59BS7"/>
        </identifiers>
        <balance>188314</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>98576729.58</valUSD>
        <pctVal>2.2998484517</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Marvell Technology Inc</name>
        <lei>N/A</lei>
        <title>Marvell Technology Inc COM</title>
        <cusip>573874104</cusip>
        <identifiers>
          <isin value="US5738741041"/>
          <ticker value="MRVL"/>
          <other otherDesc="SEDOL" value="BNKJSM5"/>
        </identifiers>
        <balance>1319636</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>130709945.8</valUSD>
        <pctVal>3.0495337769</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Medline Inc.</name>
        <lei>984500FAN6J1P8566D43</lei>
        <title>Medline Inc. COM CL A</title>
        <cusip>58507V107</cusip>
        <identifiers>
          <isin value="US58507V1070"/>
          <ticker value="MDLN"/>
          <other otherDesc="SEDOL" value="BNBV4B1"/>
        </identifiers>
        <balance>1220588</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>54316166</valUSD>
        <pctVal>1.2672255492</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Hong Kong Exchanges &amp; Clearing Ltd.</name>
        <lei>213800YTVSXYQN17BW16</lei>
        <title>Hong Kong Exchanges &amp; Clearing Ltd. NPV</title>
        <cusip>Y3506N139</cusip>
        <identifiers>
          <isin value="HK0388045442"/>
          <ticker value="HKXCF"/>
          <other otherDesc="SEDOL" value="6267359"/>
        </identifiers>
        <balance>2229400</balance>
        <units>NS</units>
        <currencyConditional curCd="HKD" exchangeRt="7.841"/>
        <valUSD>113000713.03</valUSD>
        <pctVal>2.6363677920</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>HK</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Nexstar Media Group Inc</name>
        <lei>52990083ZRR5UT591988</lei>
        <title>Nexstar Media Group Inc COM USD0.01 CL'A'</title>
        <cusip>65336K103</cusip>
        <identifiers>
          <isin value="US65336K1034"/>
          <ticker value="NXST"/>
          <other otherDesc="SEDOL" value="2949758"/>
        </identifiers>
        <balance>630593</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>114030132.19</valUSD>
        <pctVal>2.6603846981</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Oracle Corp.</name>
        <lei>1Z4GXXU7ZHVWFCD8TV52</lei>
        <title>Oracle Corp. COM USD0.01</title>
        <cusip>68389X105</cusip>
        <identifiers>
          <isin value="US68389X1054"/>
          <ticker value="ORCL"/>
          <other otherDesc="SEDOL" value="2661568"/>
        </identifiers>
        <balance>1901368</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>279710246.48</valUSD>
        <pctVal>6.5257914321</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PNC Financial Services Group Inc.</name>
        <lei>CFGNEKW0P8842LEUIA51</lei>
        <title>PNC Financial Services Group Inc. COM USD5</title>
        <cusip>693475105</cusip>
        <identifiers>
          <isin value="US6934751057"/>
          <ticker value="PNC"/>
          <other otherDesc="SEDOL" value="2692665"/>
        </identifiers>
        <balance>979554</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>203835391.86</valUSD>
        <pctVal>4.7555900097</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Revolution Medicines Inc</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>Revolution Medicines Inc COM</title>
        <cusip>76155X100</cusip>
        <identifiers>
          <isin value="US76155X1000"/>
          <ticker value="RVMD"/>
          <other otherDesc="SEDOL" value="BL71K91"/>
        </identifiers>
        <balance>232000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>22562000</valUSD>
        <pctVal>0.5263836708</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Robinhood Markets Inc</name>
        <lei>213800FS5AO3YWIE6F63</lei>
        <title>Robinhood Markets Inc COM CL A</title>
        <cusip>770700102</cusip>
        <identifiers>
          <isin value="US7707001027"/>
          <ticker value="HOOD"/>
          <other otherDesc="SEDOL" value="BP0TQN6"/>
        </identifiers>
        <balance>568536</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>39399544.8</valUSD>
        <pctVal>0.9192127036</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Sotera Health Company</name>
        <lei>N/A</lei>
        <title>Sotera Health Company COM</title>
        <cusip>83601L102</cusip>
        <identifiers>
          <isin value="US83601L1026"/>
          <ticker value="SHC"/>
          <other otherDesc="SEDOL" value="BNKVRZ7"/>
        </identifiers>
        <balance>4853280</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>69596035.2</valUSD>
        <pctVal>1.6237131672</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Structure Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>Structure Therapeutics Inc SPONSORED ADS</title>
        <cusip>86366E106</cusip>
        <identifiers>
          <isin value="US86366E1064"/>
          <ticker value="GPCR"/>
          <other otherDesc="SEDOL" value="BQS9486"/>
        </identifiers>
        <balance>329472</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>15880550.4</valUSD>
        <pctVal>0.3705018355</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetConditional assetCat="OTHER" desc="GDR"/>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Janus Henderson Cash Liquidity Fund LLC</name>
        <lei>N/A</lei>
        <title>Janus Henderson Cash Liquidity Fund LLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="895"/>
        </identifiers>
        <balance>8061749.4174</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8061749.42</valUSD>
        <pctVal>0.1880849771</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>PF</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Flutter Entertainment PLC</name>
        <lei>635400EG4YIJLJMZJ782</lei>
        <title>Flutter Entertainment PLC ORD EUR0.09 (DI)</title>
        <cusip>G3643J108</cusip>
        <identifiers>
          <isin value="IE00BWT6H894"/>
          <ticker value="FLUT"/>
          <other otherDesc="SEDOL" value="BWZMZF4"/>
        </identifiers>
        <balance>786628</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>80196724.6</valUSD>
        <pctVal>1.8710329881</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Sportradar Group AG</name>
        <lei>549300H1P33YOAT7Z533</lei>
        <title>Sportradar Group AG CLASS A ORD SHS</title>
        <cusip>H8088L103</cusip>
        <identifiers>
          <isin value="CH1134239669"/>
          <ticker value="SRAD"/>
          <other otherDesc="SEDOL" value="BMGSDH9"/>
        </identifiers>
        <balance>2271181</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>38019569.94</valUSD>
        <pctVal>0.8870171432</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Nebius Group N.V.</name>
        <lei>549300GGZHJ5Q1B18P93</lei>
        <title>Nebius Group N.V. COM USD0.01 CL 'A'</title>
        <cusip>N97284108</cusip>
        <identifiers>
          <isin value="NL0009805522"/>
          <ticker value="NBIS"/>
          <other otherDesc="SEDOL" value="B5BSZB3"/>
        </identifiers>
        <balance>1917854</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>198996531.04</valUSD>
        <pctVal>4.6426967679</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="40519115.839999996000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Amazon.com, Inc.</name>
        <lei>ZXTILKJKG63JELOEG630</lei>
        <title>Amazon.com, Inc. COM USD0.01</title>
        <cusip>023135106</cusip>
        <identifiers>
          <isin value="US0231351067"/>
          <ticker value="AMZN"/>
          <other otherDesc="SEDOL" value="2000019"/>
        </identifiers>
        <balance>1000898</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>208457026.46</valUSD>
        <pctVal>4.8634152462</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Argenx SE</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
        <title>Argenx SE SPON ADR EACH REP 1 ORD SHS</title>
        <cusip>04016X101</cusip>
        <identifiers>
          <isin value="US04016X1019"/>
          <ticker value="ARGX"/>
          <other otherDesc="SEDOL" value="BDVLM39"/>
        </identifiers>
        <balance>144283</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>105362660.75</valUSD>
        <pctVal>2.4581678985</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetConditional assetCat="OTHER" desc="GDR"/>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Baker Hughes Company</name>
        <lei>N/A</lei>
        <title>Baker Hughes Company COM USD0.0001 CL A</title>
        <cusip>05722G100</cusip>
        <identifiers>
          <isin value="US05722G1004"/>
          <ticker value="BKR"/>
          <other otherDesc="SEDOL" value="BDHLTQ5"/>
        </identifiers>
        <balance>942746</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>57554643.3</valUSD>
        <pctVal>1.3427809773</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Blackstone Inc</name>
        <lei>5299004LW4QWGZUB8Y96</lei>
        <title>Blackstone Inc COM USD0.00001 CLASS A</title>
        <cusip>09260D107</cusip>
        <identifiers>
          <isin value="US09260D1072"/>
          <ticker value="BX"/>
          <other otherDesc="SEDOL" value="BKF2SL7"/>
        </identifiers>
        <balance>481680</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>55388383.2</valUSD>
        <pctVal>1.2922409568</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>OTCOption/CALL American Equity.LUMENTUM HLDG_US_US</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="CAXXDB6U"/>
        </identifiers>
        <balance>-500</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-130775.35</valUSD>
        <pctVal>-0.0030510597</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="N/A" issuerCat="OTHER"/>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <optionSwaptionWarrantDeriv derivCat="OPT">
            <counterparties>
              <counterpartyName>JPMorgan Chase Bank, National Association</counterpartyName>
              <counterpartyLei>7H6GLXDRUGQFU57RNE97</counterpartyLei>
            </counterparties>
            <putOrCall>Call</putOrCall>
            <writtenOrPur>Written</writtenOrPur>
            <descRefInstrmnt>
              <otherRefInst>
                <issuerName>Lumentum Holdings Inc</issuerName>
                <issueTitle>Lumentum Holdings Inc</issueTitle>
                <identifiers>
                  <cusip value="55024U109"/>
                  <isin value="US55024U1097"/>
                  <ticker value="LITE"/>
                </identifiers>
              </otherRefInst>
            </descRefInstrmnt>
            <shareNo>100</shareNo>
            <exercisePrice>1000.000000000000</exercisePrice>
            <exercisePriceCurCd>USD</exercisePriceCurCd>
            <expDt>2026-04-17</expDt>
            <delta>XXXX</delta>
            <unrealizedAppr>869224.65</unrealizedAppr>
          </optionSwaptionWarrantDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Builders Firstsource, Inc.</name>
        <lei>549300W0SKP6L3H7DP63</lei>
        <title>Builders Firstsource, Inc. COM USD0.01</title>
        <cusip>12008R107</cusip>
        <identifiers>
          <isin value="US12008R1077"/>
          <ticker value="BLDR"/>
          <other otherDesc="SEDOL" value="B0BV2M7"/>
        </identifiers>
        <balance>678709</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>55878111.97</valUSD>
        <pctVal>1.3036665940</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Caesars Entertainment Inc.</name>
        <lei>549300FA4CTCW903Y781</lei>
        <title>Caesars Entertainment Inc. COM</title>
        <cusip>12769G100</cusip>
        <identifiers>
          <isin value="US12769G1004"/>
          <ticker value="CZR"/>
          <other otherDesc="SEDOL" value="BMWWGB0"/>
        </identifiers>
        <balance>5841506</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>154391003.58</valUSD>
        <pctVal>3.6020256713</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Surgery Partners Inc</name>
        <lei>549300LC82HG33S19I03</lei>
        <title>Surgery Partners Inc COM USD0.01</title>
        <cusip>86881A100</cusip>
        <identifiers>
          <isin value="US86881A1007"/>
          <ticker value="SGRY"/>
          <other otherDesc="SEDOL" value="BYTC1B2"/>
        </identifiers>
        <balance>12979640</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>154717308.8</valUSD>
        <pctVal>3.6096385487</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Taiwan Semiconductor Manufacturing Co., Ltd.</name>
        <lei>549300KB6NK5SBD14S87</lei>
        <title>Taiwan Semiconductor Manufacturing Co., Ltd. SPON ADS REP 5 ORD TWD10</title>
        <cusip>874039100</cusip>
        <identifiers>
          <isin value="US8740391003"/>
          <ticker value="TSM"/>
          <other otherDesc="SEDOL" value="2113382"/>
        </identifiers>
        <balance>720924</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>243636265.8</valUSD>
        <pctVal>5.6841659393</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetConditional assetCat="OTHER" desc="GDR"/>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>3M Company</name>
        <lei>LUZQVYP4VS22CLWDAR65</lei>
        <title>3M Company COM USD0.01</title>
        <cusip>88579Y101</cusip>
        <identifiers>
          <isin value="US88579Y1010"/>
          <ticker value="MMM"/>
          <other otherDesc="SEDOL" value="2595708"/>
        </identifiers>
        <balance>787512</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>114370367.76</valUSD>
        <pctVal>2.6683225781</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UnitedHealth Group Inc.</name>
        <lei>549300GHBMY8T5GXDE41</lei>
        <title>UnitedHealth Group Inc. COM USD0.01</title>
        <cusip>91324P102</cusip>
        <identifiers>
          <isin value="US91324P1021"/>
          <ticker value="UNH"/>
          <other otherDesc="SEDOL" value="2917766"/>
        </identifiers>
        <balance>458219</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>123989479.21</valUSD>
        <pctVal>2.8927416542</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vaxcyte Inc</name>
        <lei>254900M7NMHTGASX8D95</lei>
        <title>Vaxcyte Inc COM</title>
        <cusip>92243G108</cusip>
        <identifiers>
          <isin value="US92243G1085"/>
          <ticker value="PCVX"/>
          <other otherDesc="SEDOL" value="BKPVGH6"/>
        </identifiers>
        <balance>669842</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>38924518.62</valUSD>
        <pctVal>0.9081300857</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Vertiv Holdings Co</name>
        <lei>549300KTTIRAOGXCRV69</lei>
        <title>Vertiv Holdings Co COM CL A</title>
        <cusip>92537N108</cusip>
        <identifiers>
          <isin value="US92537N1081"/>
          <ticker value="VRT"/>
          <other otherDesc="SEDOL" value="BL3LWS8"/>
        </identifiers>
        <balance>795752</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>199399536.16</valUSD>
        <pctVal>4.6520990955</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Western Alliance Bancorp</name>
        <lei>5493003VJXZ5JXT9S762</lei>
        <title>Western Alliance Bancorp COM USD0.0001</title>
        <cusip>957638109</cusip>
        <identifiers>
          <isin value="US9576381092"/>
          <ticker value="WAL"/>
          <other otherDesc="SEDOL" value="B0CCGJ4"/>
        </identifiers>
        <balance>1325524</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>93913375.4</valUSD>
        <pctVal>2.1910498749</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Wingstop Inc</name>
        <lei>549300SSH3F8HPIM3Q47</lei>
        <title>Wingstop Inc COM USD0.01</title>
        <cusip>974155103</cusip>
        <identifiers>
          <isin value="US9741551033"/>
          <ticker value="WING"/>
          <other otherDesc="SEDOL" value="BYYXHN4"/>
        </identifiers>
        <balance>441769</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>68460941.93</valUSD>
        <pctVal>1.5972308269</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Bullish</name>
        <lei>N/A</lei>
        <title>Bullish ORD SHS</title>
        <cusip>G16910120</cusip>
        <identifiers>
          <isin value="KYG169101204"/>
          <ticker value="BLSH"/>
          <other otherDesc="SEDOL" value="BV6KVT6"/>
        </identifiers>
        <balance>1040858</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>37189856.34</valUSD>
        <pctVal>0.8676594759</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="25971992.610000000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>N/A</name>
        <lei>N/A</lei>
        <title>Royal Bank of Canada</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="RBC SL TD"/>
        </identifiers>
        <balance>13580313</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>13580313</valUSD>
        <pctVal>0.3168360521</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2026-04-01</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>3.65</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <securityLending>
          <cashCollateralCondition cashCollateralVal="13580313.000000000000" isCashCollateral="Y"/>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Janus Henderson Cash Collateral Fund LLC</name>
        <lei>N/A</lei>
        <title>Janus Henderson Cash Collateral Fund LLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal ID" value="896"/>
        </identifiers>
        <balance>54321254</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>54321254</valUSD>
        <pctVal>1.2673442550</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>PF</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <cashCollateralCondition cashCollateralVal="54321254.000000000000" isCashCollateral="Y"/>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2026-05-15</ncom:dateSigned>
      <ncom:nameOfApplicant>JANUS INVESTMENT FUND</ncom:nameOfApplicant>
      <ncom:signature>JESPER NERGAARD</ncom:signature>
      <ncom:signerName>JESPER NERGAARD</ncom:signerName>
      <ncom:title>VP, CFO, TREASURER, AND PRINCIPAL ACCOUNTING OFFICER</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
