-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 JwQgjc9QsIAe520982B/xs1kNS/UUjlbB4CScgS8yLOZ/bGItSGz4L8/vhugqYIl
 Kr8XJzwrceR0leZlw3QAtg==

<SEC-DOCUMENT>0000919574-07-001481.txt : 20070221
<SEC-HEADER>0000919574-07-001481.hdr.sgml : 20070221
<ACCEPTANCE-DATETIME>20070221162706
ACCESSION NUMBER:		0000919574-07-001481
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20070215
FILED AS OF DATE:		20070221
DATE AS OF CHANGE:		20070221

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			COLUMBIA LABORATORIES INC
		CENTRAL INDEX KEY:			0000821995
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				592758596
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		354 EISENHOWER PARKWAY
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039
		BUSINESS PHONE:		9739943999

	MAIL ADDRESS:	
		STREET 1:		354 EISENHOWER PARKWAY
		CITY:			LIVINGSTON
		STATE:			NJ
		ZIP:			07039

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			CURRAN JOHN P
		CENTRAL INDEX KEY:			0000026256

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-10352
		FILM NUMBER:		07639167

	BUSINESS ADDRESS:	
		STREET 1:		CURRAN PARTNERS LP
		STREET 2:		230 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10017
		BUSINESS PHONE:		2128082400

	MAIL ADDRESS:	
		STREET 1:		CURRAN PARTNERS LP
		STREET 2:		230 PARK AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			1010017
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>p749134_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2007-02-15</periodOfReport>

    <notSubjectToSection16>1</notSubjectToSection16>

    <issuer>
        <issuerCik>0000821995</issuerCik>
        <issuerName>COLUMBIA LABORATORIES INC</issuerName>
        <issuerTradingSymbol>CBRX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000026256</rptOwnerCik>
            <rptOwnerName>CURRAN JOHN P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>CURRAN PARTNERS LP</rptOwnerStreet1>
            <rptOwnerStreet2>230 PARK AVENUE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10017</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-02-15</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>144509</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.399</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>5049611</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Footnote</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2007-02-16</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>178991</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.4052</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4870620</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Footnote</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These shares are held in accounts of private investment funds and managed accounts over which the Reporting Person has
 investment discretion.  The Reporting Person disclaims beneficial ownership of the reported securities except to the extent
 of his pecuniary interest therein, and this report will not be deemed an admission that such Reporting Person is the
 beneficial owner of the securities for purposes of Section 16 of the Exchange Act of 1934, as amended, or for any other
purpose.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ John P. Curran</signatureName>
        <signatureDate>2007-02-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----