Mandatory Redeemable Preferred Stock and Stockholders' Equity (Deficit) - Schedule of Outstanding Awards Issued to Share-based Payment Award Plan and Inducement Grants (Parenthetical) (Details)	12 Months Ended
	Dec. 31, 2022 $ / shares
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-based Payment Award, Award Vesting Rights	(1) The number of PSUs represents the number of PSUs that will vest.      (2) The number of remaining shares of common stock available for future issuance is based on the number of PSUs that will vest.   (3) As of December 31, 2022, outstanding options have exercise prices ranging from $53.5 to $136.5 and will expire on March 30, 2023, due to termination of employees except for awards for one employee and several consultants. Unvested RSUs will vest until July 2024. The unvested PSUs will vest until April 2025.   (4) As of December 31, 2022, outstanding options have exercise prices ranging from $221.5 to $446 and will expire on March 30, 2023, due to termination of employees except for awards for one employee and several consultants.   (5) As of December 31, 2022, outstanding options have exercise prices ranging from $90 to $446 and will expire on March 30, 2023 due to termination of employees except for awards for one employee and several consultants.
Options [Member] | 2019 Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Exercise price range, lower limit	$ 53.5
Exercise price range, upper limit	136.5
Options [Member] | 2012 Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Exercise price range, lower limit	221.5
Exercise price range, upper limit	446
Options [Member] | 2009 Plan [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Exercise price range, lower limit	90
Exercise price range, upper limit	$ 446