Commitments and Contingencies - Additional Information (Details)			1 Months Ended		12 Months Ended
	Dec. 30, 2022 USD ($)	Sep. 06, 2022 USD ($)	Dec. 31, 2022 USD ($) Option	Sep. 30, 2021 Executive	Dec. 31, 2022 USD ($) Option Suite	Dec. 31, 2021 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)	Aug. 01, 2019 ft²	Jun. 01, 2019 ft²	Oct. 02, 2018 ft²
Recorded Unconditional Purchase Obligation [Line Items]
Net rentable area | ft²											56,212
Rented area lease | ft²											7,561
Additional rented area occupied under the lease | ft²									48,651	6,536
Operating lease term									11 years
Number of options to extend lease | Option			2		2
Lease renewal term			5 years		5 years
Impairment of right of use asset					$ 0
Operating lease expense					1,400,000	$ 2,100,000
Variable lease payment					700,000	700,000
Rental income on sublease					$ 400,000
Number of suites sublease | Suite					2
Number of senior executives agreed for separation excluding former EVP and former CEO | Executive				3
Share-based payment compensation costs					$ 11,572,000	18,125,000
Matching contribution percentage					4.00%
Maximum matching contribution per year					$ 2,000
Defined contribution plan vesting service period					5 years
Contributions under plan					$ 500,000	600,000
Defined contribution plan vesting percentage					100.00%
Executive Officer [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Severance expenses		$ 4,800,000				12,400,000
Share-based payment compensation costs		$ 3,200,000				$ 8,000,000.0
Chief Financial Officer [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Severance expenses			$ 6,000,000.0
Share-based payment compensation costs			$ 1,100,000
Prepaid Expenses and Other Current Assets [Member] | Paragraph Four Certification Notice Letter [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Legal proceeding costs					$ 2,300,000
BIJUVA [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Minimum supply commitment fee percentage payable			50.00%		50.00%
IMVEXXY [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Minimum supply commitment fee percentage payable			60.00%		60.00%
Mayne License Agreement [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Cash received for net working capital	$ 12,100,000
Measurement adjustments period	2 years
Prepaid royalties received	$ 1,000,000.0
Quarterly royalty payment	$ 257,250
Quarterly royalty payment, interest per annum	19.00%
Quarterly royalty payment reduced from consideration assuming obligations	$ 1,500,000
Population Council License Agreement [Member] | Annoveras
Recorded Unconditional Purchase Obligation [Line Items]
Milestone payment							$ 20,000,000.0	$ 20,000,000.0
Milestone payments recorded as license rights					$ 40,000,000.0
Costs and expenses associated with post approval study					$ 20,000,000.0