Licensed rights and other intangible assets - Summary of Information about License Rights and Other Intangible Assets, Net (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	$ 48,024	$ 47,854
Finite-Lived Intangible Assets, Accumulated Amortization	8,809	7,868
Finite-Lived Intangible Assets, Net	39,215	39,986
License Rights and Intangible Assets, Net, Gross Carrying Amount (Excluding Goodwill)	48,356	48,186
License rights and other intangible assets, net	39,547	40,318
License rights [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	40,000	40,000
Finite-Lived Intangible Assets, Accumulated Amortization	7,580	6,826
Finite-Lived Intangible Assets, Net	32,420	33,174
Hormone therapy drug patents [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	6,117	5,834
Finite-Lived Intangible Assets, Accumulated Amortization	1,229	1,042
Finite-Lived Intangible Assets, Net	4,888	4,792
Hormone therapy drug candidate patents - applied and pending [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	1,907	2,020
Finite-Lived Intangible Assets, Net	1,907	2,020
Trademarks/trade name rights [Member]
Finite-Lived Intangible Assets [Line Items]
Indefinite-Lived Intangible Assets, Gross Carrying Amount and Net	$ 332	$ 332