Summary quarterly information (unaudited) - Summary of Quarterly Information (Parenthetical) (Details) - USD ($) $ in Thousands	3 Months Ended												12 Months Ended
	Dec. 31, 2021		Sep. 30, 2021		Jun. 30, 2021	Mar. 31, 2021	Dec. 31, 2020		Sep. 30, 2020		Jun. 30, 2020	Mar. 31, 2020	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue, net	$ 18,678	[1]	$ 25,406	[2]	$ 23,001	$ 19,866	$ 22,578	[3]	$ 19,342	[4]	$ 10,701	$ 12,251	$ 86,951	$ 64,872	$ 49,647
Inventory charge									5,700
Write-off of patent and trademark							$ 500		600				$ 0	$ 1,132	$ 79
Knight License Agreement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total revenue, net									$ 2,000
Senior Executive [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount in severances	$ 5,100		$ 7,300

[1] Included $5.1 million in senior executive severances, which included our former CEO.

[2] Included $7.3 million in senior executive severances, which included our former EVP of Operations.

[3] Included $0.5 million in write off of certain costs related to trademarks and patents.

[4] Included (i) $2.0 million in license revenue related to the Knight License Agreement, (ii) $5.7 million in inventory charge, primarily related to BIJUVA, and (iii) $0.6 million in write off of certain costs related to trademarks and patents.